公开(公告)号：US20060129197A1

公开(公告)日：2006-06-15

申请号：US11012433

申请日：2004-12-15

申请人： Geng Zhang ,  Ankur Garg ,  Douglas Daum

发明人： Geng Zhang ,  Ankur Garg ,  Douglas Daum

IPC分类号： A61N1/365

CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

摘要： Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient's heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response.

公开(公告)号：US20090306737A1

公开(公告)日：2009-12-10

申请号：US12540902

申请日：2009-08-13

申请人： Geng Zhang ,  Ankur Garg ,  Douglas R. Daum

发明人： Geng Zhang ,  Ankur Garg ,  Douglas R. Daum

IPC分类号： A61N1/37

CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

摘要： Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient's heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response.

摘要翻译： 描述了用于将心脏反应分类为起搏刺激和/或预防逆行心脏传导的方法和系统。 在心脏周期内将起搏脉搏递送到患者心脏的心房后，系统在心房感测逆行P波。 该系统基于逆行P波的检测将起搏脉冲的心房响应分类。 该系统还可以感知心房诱发反应并且利用心房诱发反应来分类心脏起搏反应。

公开(公告)号：US20060129199A1

公开(公告)日：2006-06-15

申请号：US11012692

申请日：2004-12-15

申请人： Geng Zhang ,  Ankur Garg

发明人： Geng Zhang ,  Ankur Garg

IPC分类号： A61N1/365

CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

摘要： Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient's heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response. If capture is not detected, the system may deliver additional atrial pacing pulses to reduce atrial retrograde conduction. A backup pace may be delivered to prevent the atrial retrograde conduction if an atrial evoked response is not detected during a cardiac cycle. Alternatively, retrograde management may involve delaying a next scheduled pace may be until expiration of an atrial effective refractory period.

摘要翻译： 描述了用于将心脏反应分类为起搏刺激和/或预防逆行心脏传导的方法和系统。 在心脏周期内将起搏脉搏递送到患者心脏的心房后，系统在心房感测逆行P波。 该系统基于逆行P波的检测将起搏脉冲的心房响应分类。 该系统还可以感知心房诱发反应并且利用心房诱发反应来分类心脏起搏反应。 如果未检测到捕获，则系统可能会传递额外的心房起搏脉冲以减少心房逆行传导。 如果在心动周期期间没有检测到心房诱发反应，则可以提供备份速度以防止心房逆行传导。 或者，逆行管理可能涉及延迟下一预定速度，直到心房有效不应期结束。

公开(公告)号：US07957803B2

公开(公告)日：2011-06-07

申请号：US12540902

申请日：2009-08-13

申请人： Geng Zhang ,  Ankur Garg ,  Douglas R. Daum

发明人： Geng Zhang ,  Ankur Garg ,  Douglas R. Daum

IPC分类号： A61N1/37

CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

摘要： Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient's heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response.

摘要翻译： 描述了用于将心脏反应分类为起搏刺激和/或预防逆行心脏传导的方法和系统。 在心脏周期内将起搏脉搏递送到患者心脏的心房后，系统在心房感测逆行P波。 该系统基于逆行P波的检测将起搏脉冲的心房响应分类。 该系统还可以感知心房诱发反应并且利用心房诱发反应来分类心脏起搏反应。

公开(公告)号：US08229561B2

公开(公告)日：2012-07-24

申请号：US11012692

申请日：2004-12-15

申请人： Geng Zhang ,  Ankur Garg

发明人： Geng Zhang ,  Ankur Garg

IPC分类号： A61N1/365

CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

摘要： Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient's heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response. If capture is not detected, the system may deliver additional atrial pacing pulses to reduce atrial retrograde conduction. A backup pace may be delivered to prevent the atrial retrograde conduction if an atrial evoked response is not detected during a cardiac cycle. Alternatively, retrograde management may involve delaying a next scheduled pace may be until expiration of an atrial effective refractory period.

摘要翻译： 描述了用于将心脏反应分类为起搏刺激和/或预防逆行心脏传导的方法和系统。 在心脏周期内将起搏脉搏递送到患者心脏的心房后，系统在心房感测逆行P波。 该系统基于逆行P波的检测将起搏脉冲的心房响应分类。 该系统还可以感知心房诱发反应并且利用心房诱发反应来分类心脏起搏反应。 如果未检测到捕获，则系统可能会传递额外的心房起搏脉冲以减少心房逆行传导。 如果在心动周期期间没有检测到心房诱发反应，则可以提供备份速度以防止心房逆行传导。 或者，逆行管理可能涉及延迟下一预定速度，直到心房有效不应期结束。

公开(公告)号：US07587240B2

公开(公告)日：2009-09-08

申请号：US11012433

申请日：2004-12-15

申请人： Geng Zhang ,  Ankur Garg ,  Douglas R. Daum

发明人： Geng Zhang ,  Ankur Garg ,  Douglas R. Daum

IPC分类号： A61N1/365

CPC分类号： A61N1/3712 ,  A61N1/3622 ,  A61N1/3714

摘要： Methods and systems for classifying cardiac responses to pacing stimulation and/or preventing retrograde cardiac conduction are described. Following delivery of a pacing pulse to an atrium of the patient'heart during a cardiac cycle, the system senses in the atrium for a retrograde P-wave. The system classifies the atrial response to the pacing pulse based on detection of the retrograde P-wave. The system may also sense for an atrial evoked response and utilize the atrial evoked response in classifying the cardiac pacing response.

摘要翻译： 描述了用于将心脏反应分类为起搏刺激和/或预防逆行心脏传导的方法和系统。 在心脏周期内将起搏脉搏递送到患者心脏的心房后，系统在心房感测逆行P波。 该系统基于逆行P波的检测将起搏脉冲的心房响应分类。 该系统还可以感知心房诱发反应并且利用心房诱发反应来分类心脏起搏反应。

公开(公告)号：US20050288719A1

公开(公告)日：2005-12-29

申请号：US10858848

申请日：2004-06-02

申请人： Geng Zhang ,  Douglas Daum ,  James Gilkerson ,  Quan Ni

发明人： Geng Zhang ,  Douglas Daum ,  James Gilkerson ,  Quan Ni

IPC分类号： A61N1/362 ,  A61N1/37 ,  A61N1/375

CPC分类号： A61N1/371 ,  A61N1/3621 ,  A61N1/3756

摘要： An implantable pacemaker is provided with a far-field sensing channel which requires a reduced refractory period during the time when pacing pulses are delivered as compared with sensing channels using intra-cardiac electrodes. The far-field sensing channel may use the conductive housing of the implantable device or can and an indifferent electrode mounted on the device header as the electrodes for its differential inputs. Such a far-field sensing channel is able to sense activity occurring in either the atria or the ventricles for the purposes of arrhythmia detection and/or capture verification.

摘要翻译： 植入式心脏起搏器设置有远场感测通道，与使用心脏内电极的感测通道相比，在进行起搏脉冲的时间期间需要减少的不应期。 远场感测通道可以使用可植入装置的导电外壳或者可以将安装在设备头上的无关电极用作其差分输入的电极。 为了心律失常检测和/或捕获验证的目的，这种远场感测通道能够感测在心房或心室中发生的活动。

公开(公告)号：US20050197674A1

公开(公告)日：2005-09-08

申请号：US10795126

申请日：2004-03-05

申请人： Aaron McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas Daum

发明人： Aaron McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas Daum

IPC分类号： A61B5/0402 ,  A61N1/365 ,  A61N1/375 ,  A61N1/362

CPC分类号： A61B5/0402 ,  A61N1/365 ,  A61N1/3756

摘要： An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.

摘要翻译： 诸如可植入起搏器或植入式心律转复/除颤器的可植入医疗装置包括可编程感测电路，用于通过植入电极感测接近表面心电图（ECG）的信号。 通过各种电极配置，获取近似各种标准表面ECG信号的信号，而不需要将电极与电缆连接在皮肤上。 各种电极配置包括但不限于心脏内起搏电极，可植入医疗器械接触组织的部分和结合到可植入医疗装置的表面上的电极的各种组合。

公开(公告)号：US20080051672A1

公开(公告)日：2008-02-28

申请号：US11925657

申请日：2007-10-26

申请人： Aaron McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas Daum

发明人： Aaron McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas Daum

IPC分类号： A61B5/0402

CPC分类号： A61B5/0402 ,  A61N1/365 ,  A61N1/3756

摘要： An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.

摘要翻译： 诸如可植入起搏器或植入式心律转复/除颤器的可植入医疗装置包括可编程感测电路，用于通过植入电极感测接近表面心电图（ECG）的信号。 通过各种电极配置，获取近似各种标准表面ECG信号的信号，而不需要将电极与电缆连接在皮肤上。 各种电极配置包括但不限于心脏内起搏电极，可植入医疗器械接触组织的部分和结合到可植入医疗装置的表面上的电极的各种组合。

公开(公告)号：US20060009812A1

公开(公告)日：2006-01-12

申请号：US11225712

申请日：2005-09-13

申请人： Douglas Daum ,  Geng Zhang ,  Qingsheng Zhu ,  Gerrard Carlson ,  Julio Spinelli

发明人： Douglas Daum ,  Geng Zhang ,  Qingsheng Zhu ,  Gerrard Carlson ,  Julio Spinelli

IPC分类号： A61N1/37

CPC分类号： A61N1/365

摘要： A maximum pacing rate limiter for use in adaptive rate pacing in conjunction with a cardiac rhythm management system for a heart. The maximum pacing rate limiter may function to measure an interval, termed the ERT interval, between a paced ventricular evoked response and a T-wave. The maximum pacing rate limiter may further function to maintain the ERT interval at less than a certain percentage of the total cardiac cycle. In one disclosed embodiment, a maximum pacing rate limiter calculates an ERT rate based on the detected paced ventricular evoked response and the T-wave, and the pacing rate limiter module further communicates the minimum of the ERT rate and an adaptive-rate sensor indicated rate to a pacemaker.

摘要翻译： 与心脏心律管理系统结合使用的适应性起搏速度的最大起搏速率限制器。 最大起搏速率限制器可以用于测量在起搏心室诱发反应和T波之间的称为ERT间期的间隔。 最大起搏速率限制器可进一步起作用以将ERT间期维持在小于总心律周期的一定百分比。 在一个公开的实施例中，最大起搏速率限制器基于检测到的起搏心室诱发反应和T波计算ERT率，并且起搏速率限制器模块进一步传达最小ERT率和自适应速率传感器指示率 到起搏器。