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公开(公告)号：US20180373837A1
公开(公告)日：2018-12-27
申请号：US16117976
申请日：2018-08-30
IPC分类号： G06F19/22 , G01N33/487
摘要： A system includes a plurality of nanopore cells. Data corresponding to nanopore states of the plurality of nanopore cells is received. The data is analyzed to determine a compressed output size of the data given at least one compression technique. It is determined whether the compressed output size exceeds a data budget. In the event it is determined that the compressed output size exceeds the data budget, the data is modified. The modified data is outputted.
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公开(公告)号：US20170284962A1
公开(公告)日：2017-10-05
申请号：US15487825
申请日：2017-04-14
IPC分类号： G01N27/447 , G01N27/403 , G01N33/487 , C12Q1/68
CPC分类号： G01N27/44791 , C12Q1/6869 , G01N27/403 , G01N33/48721 , C12Q2527/125 , C12Q2565/607 , C12Q2565/629 , C12Q2565/631
摘要： A nanopore based sequencing chip package is disclosed. The nanopore based sequencing chip package includes a reservoir defined by a plurality of surfaces. The chip package includes a nanopore cell array comprising a plurality of nanopore sensor cells enclosed by the reservoir. Each nanopore sensor cell has a working electrode. At least one surface of the reservoir is configured to be in contact with a conducting fluid when the conducting fluid is flowing through the reservoir. The chip package further includes a counter electrode disposed on the at least one surface of the reservoir.
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公开(公告)号：US11361843B2
公开(公告)日：2022-06-14
申请号：US16117976
申请日：2018-08-30
IPC分类号： G01N33/48 , G01N33/50 , G16B30/00 , G01N33/487
摘要： A system includes a plurality of nanopore cells. Data corresponding to nanopore states of the plurality of nanopore cells is received. The data is analyzed to determine a compressed output size of the data given at least one compression technique. It is determined whether the compressed output size exceeds a data budget. In the event it is determined that the compressed output size exceeds the data budget, the data is modified. The modified data is outputted.
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公开(公告)号：US20180136159A1
公开(公告)日：2018-05-17
申请号：US15820032
申请日：2017-11-21
发明人： Roger J.A. Chen , Hui Tian , J. William Maney
IPC分类号： G01N27/22 , G01N33/487 , C12Q1/6869 , G01N27/447
CPC分类号： G01N27/228 , C12Q1/6869 , G01N27/44791 , G01N33/48721 , C12Q2527/125 , C12Q2565/607 , C12Q2565/629 , C12Q2565/631
摘要： A method of analyzing a molecule is disclosed. A voltage source is selectively connected to or disconnected from a capacitor using a switch controlled by a reset signal. A charge is stored in a capacitor when the voltage source is connected to the capacitor. The capacitor is discharged through a nanopore in a membrane when the voltage source is disconnected from the capacitor. A duty cycle of the reset signal is determined such that the voltage source and the capacitor is connected for at least a one tenth portion of a reset signal period and disconnected for a remaining portion of the reset signal period, such that a voltage across the nanopore is maintained at a higher level during the portion of the reset signal period in which the connection is maintained than during the remaining portion of the reset signal period in which the connection is not maintained.
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