公开(公告)号：US20160367261A1

公开(公告)日：2016-12-22

申请号：US15002113

申请日：2016-01-20

申请人： Genzyme Corporation

发明人： Jean-Marie Vogel ,  John A. Merhige

IPC分类号： A61B17/12 ,  A61L24/00 ,  A61L24/04 ,  A61B18/04

CPC分类号： A61B17/12181 ,  A61B18/04 ,  A61K9/0019 ,  A61L24/001 ,  A61L24/0015 ,  A61L24/0031 ,  A61L24/046 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2300/408 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/418 ,  A61L2430/36 ,  A61M37/00

摘要： Precision in thermotherapy is obtained by providing a reverse gelling polymer composition which gels when its temperature is raised towards body temperature. The composition is injected into the blood supply of the tissue being treated, at the beginning of thermotherapy. The temperature increase caused by the heating rapidly gels the composition, which temporarily blocks the flow of blood in the region being treated. This improves the predictability and stability of treatment. On cessation of heating, the composition gradually dissolves, removing the temporary embolization. The use of local heating can also expedite removal of tumors and the like from soft organs, even when the heating itself has no therapeutic effect.

摘要翻译： 通过提供当其温度升高到体温时凝胶化的反胶凝聚合物组合物来获得热疗中的精确度。 在热疗开始时将组合物注射到被治疗组织的血液供应中。 由加热引起的温度升高迅速凝结组合物，这暂时阻止了被处理区域内的血液流动。 这提高了治疗的可预测性和稳定性。 加热停止时，组成逐渐溶解，消除临时栓塞。 即使加热本身没有治疗效果，使用局部加热也可以加速从软体器官中去除肿瘤等。