公开(公告)号：US20120271378A1

公开(公告)日：2012-10-25

申请号：US13532419

申请日：2012-06-25

申请人： George Van Campen ,  John Erickson

发明人： George Van Campen ,  John Erickson

IPC分类号： A61N1/36

CPC分类号： A61N1/378 ,  A61N1/3708 ,  A61N1/40

摘要： The invention relates to a stimulation device for creating complex or multi-purpose tissue stimulation. Many typical stimulation devices suffer from deficiencies in providing complex stimulation patterns. Using a circuitry operable or programmable to repeat and skip stimulation settings, a complex stimulation set may be created. The repeating and skipping functionality may be implemented in hardware or software. In this manner, complex stimulations may be derived from simple circuitries. Furthermore, these stimulations may be used to treat pain, stimulate bone growth, and control motor disorders, among others.

摘要翻译： 本发明涉及一种用于产生复合或多用途组织刺激的刺激装置。 许多典型的刺激装置在提供复杂刺激模式方面存在缺陷。 使用可操作或可编程的电路来重复和跳过刺激设置，可以创建复杂的刺激集合。 重复和跳过功能可以在硬件或软件中实现。 以这种方式，可以从简单的电路中导出复杂的刺激。 此外，这些刺激可以用于治疗疼痛，刺激骨骼生长和控制运动障碍等。

公开(公告)号：US08433416B2

公开(公告)日：2013-04-30

申请号：US13532419

申请日：2012-06-25

申请人： George Van Campen ,  John Erickson

发明人： George Van Campen ,  John Erickson

IPC分类号： A61N1/18

CPC分类号： A61N1/378 ,  A61N1/3708 ,  A61N1/40

摘要： The invention relates to a stimulation device for creating complex or multi-purpose tissue stimulation. Many typical stimulation devices suffer from deficiencies in providing complex stimulation patterns. Using a circuitry operable or programmable to repeat and skip stimulation settings, a complex stimulation set may be created. The repeating and skipping functionality may be implemented in hardware or software. In this manner, complex stimulations may be derived from simple circuitries. Furthermore, these stimulations may be used to treat pain, stimulate bone growth, and control motor disorders, among others.

摘要翻译： 本发明涉及一种用于产生复合或多用途组织刺激的刺激装置。 许多典型的刺激装置在提供复杂刺激模式方面存在缺陷。 使用可操作或可编程的电路来重复和跳过刺激设置，可以创建复杂的刺激集合。 重复和跳过功能可以在硬件或软件中实现。 以这种方式，可以从简单的电路中导出复杂的刺激。 此外，这些刺激可以用于治疗疼痛，刺激骨骼生长和控制运动障碍等。

公开(公告)号：US07228179B2

公开(公告)日：2007-06-05

申请号：US10627232

申请日：2003-07-25

申请人： George Van Campen ,  John Erickson

发明人： George Van Campen ,  John Erickson

IPC分类号： A61N1/00

CPC分类号： A61B17/3468 ,  A61N1/3708 ,  A61N1/40

摘要： The invention relates to a stimulation device for creating complex or multi-purpose tissue stimulation. Many typical stimulation devices suffer from deficiencies in providing complex stimulation patterns. Using a circuitry operable or programmable to repeat and skip stimulation settings, a complex stimulation set may be created. The repeating and skipping functionality may be implemented in hardware or software. In this manner, complex stimulations may be derived from simple circuitries. Furthermore, these stimulations may be used to treat pain, stimulate bone growth, and control motor disorders, among others.

摘要翻译： 本发明涉及一种用于产生复合或多用途组织刺激的刺激装置。 许多典型的刺激装置在提供复杂刺激模式方面存在缺陷。 使用可操作或可编程的电路来重复和跳过刺激设置，可以创建复杂的刺激集合。 重复和跳过功能可以在硬件或软件中实现。 以这种方式，可以从简单的电路中导出复杂的刺激。 此外，这些刺激可以用于治疗疼痛，刺激骨骼生长和控制运动障碍等。

公开(公告)号：US07127297B2

公开(公告)日：2006-10-24

申请号：US10444250

申请日：2003-05-23

申请人： Jay Law ,  William Borkan ,  Lance Ehren ,  George Van Campen ,  John Erickson

发明人： Jay Law ,  William Borkan ,  Lance Ehren ,  George Van Campen ,  John Erickson

IPC分类号： A61N1/36

CPC分类号： A61N1/36021 ,  A61N1/36017 ,  A61N1/36071 ,  A61N1/37229

摘要： An electronic stimulation system is used to control pain over multiple regions of a patient's body. The system has one or more percutaneous leads, each having multiple electrodes, implanted within the patient's epidural space parallel to the axis of the spinal cord. The leads are connected to either a totally implanted system or a radio frequency system. The system is able to treat pain over different regions of a patient's body by “simultaneously” stimulating the patient with at least three different stimulation settings. “Simultaneous” stimulation involves sequentially stimulating the patient with the multiple stimulation settings such that the patient receives the cumulative effect of each stimulation setting, while not perceiving the transition from one stimulation setting to another.

公开(公告)号：US06609031B1

公开(公告)日：2003-08-19

申请号：US08659919

申请日：1996-06-07

申请人： Jay Law ,  William Borkan ,  Lance Ehren ,  George Van Campen ,  John Erickson

发明人： Jay Law ,  William Borkan ,  Lance Ehren ,  George Van Campen ,  John Erickson

IPC分类号： A61N134

CPC分类号： A61N1/36021 ,  A61N1/36017 ,  A61N1/36071 ,  A61N1/37229

摘要： An electronic stimulation system is used to control pain over multiple regions of a patient's body. The system has one or more percutaneous leads, each having multiple electrodes, implanted within the patient's epidural space parallel to the axis of the spinal cord. The leads are connected to either a totally implanted system or a radio frequency system. The system is able to treat pain over different regions of a patient's body by “simultaneously” stimulating the patient with at least three different stimulation settings. “Simultaneous” stimulation involves sequentially stimulating the patient with the multiple stimulation settings such that the patient receives the cumulative effect of each stimulation setting, while not perceiving the transition from one stimulation setting to another.

摘要翻译： 电子刺激系统用于控制患者身体的多个区域的疼痛。 系统具有一个或多个经皮引线，每个具有多个电极，植入患者硬脊膜空间内平行于脊髓的轴线。 引线连接到完全植入系统或射频系统。 该系统能够通过“同时”刺激患者至少三种不同的刺激设置来治疗患者身体的不同区域的疼痛。 “同时”刺激涉及以多次刺激设置顺序地刺激患者，使得患者接收每个刺激设置的累积效应，而不感知从一个刺激设置到另一个刺激设置的过渡。

公开(公告)号：US07254445B2

公开(公告)日：2007-08-07

申请号：US10901900

申请日：2004-07-28

申请人： Jay Law ,  William Borkan ,  Lance Ehren ,  George Van Campen ,  John Erickson

发明人： Jay Law ,  William Borkan ,  Lance Ehren ,  George Van Campen ,  John Erickson

IPC分类号： A61N1/34

CPC分类号： A61N1/36021 ,  A61N1/36017 ,  A61N1/36071 ,  A61N1/37229

摘要： An electronic stimulation system is used to control pain over multiple regions of a patient's body. The system has one or more percutaneous leads, each having multiple electrodes, implanted within the patient's epidural space parallel to the axis of the spinal cord. The leads are connected to either a totally implanted system or a radio frequency system. The system is able to treat pain over different regions of a patient's body by “simultaneously” stimulating the patient with at least three different stimulation settings. “Simultaneous” stimulation involves sequentially stimulating the patient with the multiple stimulation settings such that the patient receives the cumulative effect of each stimulation setting, while not perceiving the transition from one stimulation setting to another.

摘要翻译： 电子刺激系统用于控制患者身体的多个区域的疼痛。 系统具有一个或多个经皮引线，每个具有多个电极，植入患者硬脊膜空间内平行于脊髓的轴线。 引线连接到完全植入系统或射频系统。 该系统能够通过“同时”刺激具有至少三种不同刺激设置的患者来治疗患者身体的不同区域的疼痛。 “同时”刺激涉及以多次刺激设置顺序地刺激患者，使得患者接收每个刺激设置的累积效应，而不感知从一个刺激设置到另一个刺激设置的过渡。

公开(公告)号：US20110208265A1

公开(公告)日：2011-08-25

申请号：US13099142

申请日：2011-05-02

申请人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

发明人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

IPC分类号： A61N1/36

CPC分类号： A61N1/37247 ,  A61N1/36017 ,  A61N1/3605 ,  A61N1/37241

摘要： Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses.

摘要翻译： 公开了提供适合于在手术期间和在患者试验期间使用的试验刺激物的系统和方法。 试验刺激器实施例提供了患者接口和/或临床医生界面，该接口出现并且与在试用期之后将被使用的脉冲发生器控制器的接口基本相同。 可以提供合规监测功能以便于在试用期间验证试用刺激器的正确使用。 可以提供诊断特征以便于验证试验刺激器的各个方面的正确操作，例如电极阻抗分析。 实施例的刺激器可以对身体的多个组织和/或区域提供刺激，例如脊髓刺激，深部脑刺激等。 实施例提供多电极刺激和多刺激程序。 实施例被配置为提供刺激脉冲的主动放电以及在提供刺激脉冲时利用恒定电流源。

公开(公告)号：US07359751B1

公开(公告)日：2008-04-15

申请号：US11122706

申请日：2005-05-05

申请人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

发明人： John H. Erickson ,  George Van Campen ,  Patrick M. Cullen ,  Thomas K. Hickman

IPC分类号： A61N1/08

CPC分类号： A61N1/37247 ,  A61N1/36017 ,  A61N1/3605 ,  A61N1/37241

摘要： Disclosed are systems and methods which provide an external clinician interface, such as through the use of a laptop computer or a personal digital assistant (PDA). The foregoing clinician interface may be used with trial stimulators well suited for use interoperatively and during patient trial. Stimulators of embodiments are adapted for use in providing stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera.

摘要翻译： 公开了提供外部临床医师界面的系统和方法，例如通过使用膝上型计算机或个人数字助理（PDA）。 上述临床医师界面可以与试验刺激器一起使用，其非常适合于在手术中和在患者试验期间使用。 实施例的刺激器适于用于向身体的多个组织和/或区域提供刺激，例如脊髓刺激，深部脑刺激等。

公开(公告)号：US5938690A

公开(公告)日：1999-08-17

申请号：US659874

申请日：1996-06-07

申请人： Jay Law ,  William Borkan ,  Lance Ehren ,  George Van Campen

发明人： Jay Law ,  William Borkan ,  Lance Ehren ,  George Van Campen

IPC分类号： A61N1/34 ,  A61N1/02

CPC分类号： A61N1/37235 ,  A61N1/36071 ,  A61N1/36017 ,  A61N1/37252

摘要： A computer based system and methods for use with known neuromodulation systems to assist in the performance of pre-, intra- and post-operative procedures relating to the determination and optimization of a patient's therapeutic regimen. The system can use a computer database of information in connection with the pain map of an individual patient to aid the physician in making more accurate decisions regarding waveform and electrode configuration definition, as well as multi-electrode lead placement. The system can record and process patient responses to test stimulation patterns during the operation of placing the electrodes, so as to give the physician real-time information that can be used to effectively position the multi-electrode leads within the patient's body. The system also provides computer assisted post-operative presentation and assessment of stimulation settings, which utilizes, at least in one mode of operation, an iterative, systematic approach to determining one or more optimum stimulation settings.

摘要翻译： 一种基于计算机的系统和与已知神经调节系统一起使用的方法，以协助执行与确定和优化患者治疗方案有关的术前，术中和术后手术。 该系统可以使用与单个患者的疼痛图相关联的信息的计算机数据库，以帮助医师对波形和电极配置定义以及多电极引线放置做出更准确的决定。 在放置电极的操作期间，系统可以记录和处理患者的反应以测试刺激图案，以便给予医师实时信息，以便将多电极引线有效地定位在患者体内。 该系统还提供计算机辅助的手术后呈现和刺激设置的评估，所述刺激设置利用至少一种操作模式来迭代的，系统的方法来确定一个或多个最佳刺激设置。

公开(公告)号：US07937158B2

公开(公告)日：2011-05-03

申请号：US12243632

申请日：2008-10-01

申请人： John H Erickson ,  George Van Campen ,  Patrick M Cullen ,  Thomas K Hickman

发明人： John H Erickson ,  George Van Campen ,  Patrick M Cullen ,  Thomas K Hickman

IPC分类号： A61N1/08

CPC分类号： A61N1/37247 ,  A61N1/36017 ,  A61N1/3605 ,  A61N1/37241

摘要： Disclosed are systems and methods which provide trial stimulators suited for use interoperatively and during patient trial. Trial stimulator embodiments provide a patient interface and/or clinician interface which appears and functions substantially the same as an interface of a pulse generator controller which will be used after a trial period. A compliance monitor feature may be provided to facilitate verifying the proper use of the trial stimulator during a trial period. A diagnostic feature may be provided to facilitate verifying proper operation of various aspects of a trial stimulator, such as electrode impedance analysis. Trial stimulators of embodiments provide stimulation to a plurality of tissues and/or areas of the body, such as spinal cord stimulation, deep brain stimulation, etcetera. Embodiments provide for multi-electrode stimulation and multi-stimulation programs. Embodiments are configured to provide active discharge of stimulation pulses as well as to utilize constant current sources in providing the stimulation pulses.

摘要翻译： 公开了提供适合于在手术期间和在患者试验期间使用的试验刺激物的系统和方法。 试验刺激器实施例提供了患者接口和/或临床医生界面，该接口出现并且与在试用期之后将被使用的脉冲发生器控制器的接口基本相同。 可以提供合规监测功能以便于在试用期间验证试用刺激器的正确使用。 可以提供诊断特征以便于验证试验刺激器的各个方面的正确操作，例如电极阻抗分析。 实施例的刺激器可以对身体的多个组织和/或区域提供刺激，例如脊髓刺激，深部脑刺激等。 实施例提供多电极刺激和多刺激程序。 实施例被配置为提供刺激脉冲的主动放电以及在提供刺激脉冲时利用恒定电流源。