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公开(公告)号:US20150361182A1
公开(公告)日:2015-12-17
申请号:US14730897
申请日:2015-06-04
发明人: Peidong Fan , Jong Kang , Amanda Mikels-Vigdal , Lina Yao , Hongyan Zhong
IPC分类号: C07K16/40 , G01N33/573 , A61L31/10
CPC分类号: C07K16/40 , A61K2039/505 , A61L31/10 , C07K2317/76 , G01N33/573 , G01N2333/90638 , G01N2800/325 , G01N2800/326
摘要: Provided herein are methods that relate to a novel therapeutic strategy for treatment of heart and/or cardiovascular diseases. The method includes administration of LOXL2 inhibitors for treating, preventing, or ameliorating at least one symptom associated with heart and/or cardiovascular diseases.
摘要翻译: 本文提供了涉及用于治疗心脏和/或心血管疾病的新型治疗策略的方法。 该方法包括施用LOXL2抑制剂以治疗,预防或改善与心脏和/或心血管疾病相关的至少一种症状。
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2.
公开(公告)号:US20170306050A1
公开(公告)日:2017-10-26
申请号:US15482452
申请日:2017-04-07
发明人: Jeremiah D. Degenhardt , David Gossage , Andrew Greenstein , Vladi Juric , Amanda Mikels-Vigdal , Victoria Smith , Maria Vaysberg , Peng Yue
CPC分类号: C07K16/40 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/545 , C07K16/2827 , C07K16/3015 , C07K16/3046 , C07K2317/24 , C07K2317/32 , C07K2317/34 , C07K2317/53 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/94 , C12Y304/24035 , A61K2300/00
摘要: The present disclosure provides compositions and methods of use comprising a matrix metalloproteinase-9 (MMP9) binding protein, alone or in combination with one or more additional therapeutic agents for the treatment or prevention of diseases and conditions.
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公开(公告)号:US20180155447A1
公开(公告)日:2018-06-07
申请号:US15788604
申请日:2017-10-19
发明人: Peidong Fan , Jong Kang , Amanda Mikels-Vigdal , Lina Yao , Hongyan Zhong
IPC分类号: C07K16/40 , G01N33/573 , A61L31/10 , A61K39/00
CPC分类号: C07K16/40 , A61K2039/505 , A61L31/10 , C07K2317/76 , G01N33/573 , G01N2333/90638 , G01N2800/325 , G01N2800/326
摘要: Provided herein are methods that relate to a novel therapeutic strategy for treatment of heart and/or cardiovascular diseases. The method includes administration of LOXL2 inhibitors for treating, preventing, or ameliorating at least one symptom associated with heart and/or cardiovascular diseases.
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