公开(公告)号：US20230293657A1

公开(公告)日：2023-09-21

申请号：US18001525

申请日：2021-06-17

申请人： GlaxoSmithKline Biologicals SA

发明人： Maria Paula CARRANZA SANDMEIER ,  Rainer FOLLADOR ,  Veronica Gambillara FONCK ,  Stefan Jochen KEMMLER ,  Patricia Martin KILLIAS ,  Michael Thomas KOWARIK ,  Gerd Martin LIPOWSKY ,  Gerald Johann POSCH ,  Fabio SERVENTI ,  Dominique Nicolas SIRENA

IPC分类号： A61K39/108 ,  C07K14/26 ,  A61P31/04 ,  C12N9/10

CPC分类号： A61K39/0266 ,  C07K14/26 ,  A61P31/04 ,  C12N9/1081 ,  C12Y204/99019 ,  A61K2039/6068

摘要： The present invention relates to the field of immunogenic compositions and vaccines, their manufacture, host cells which can be used in their manufacture and the use of such immunogenic compositions and vaccines in medicine. More particularly, it relates to Klebsiella pneumoniae O-antigens, conjugates comprising a K. pneumoniae O-antigen, host cells suitable for their production and immunogenic compositions or vaccines containing at least one Klebsiella pneumoniae O-antigen.