专利检索 ap:("GlaxoSmithKline Biologicals SA") AND inv:"Romain KOCKS" 第 1 页

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发明申请
FERMENTATION PROCESS 有权

公开(公告)号：US20220169973A1

公开(公告)日：2022-06-02

申请号：US17432671

申请日：2020-02-20

申请人： GlaxoSmithKline Biologicals SA

发明人： Philippe DEHOTTAY , Romain KOCKS , Quentin ZUNE

IPC分类号： C12N1/20 , C12N9/10 , C07K14/235 , A61K39/02

摘要： The present invention relates to processes for Bordetella fermentation and virulence factor production, especially PT production, for large scale manufacturing. More particularly, processes including a medium conditioning step carried out prior to inoculation.