专利检索 ap:("GlaxoSmithKline Intellectual Property (No.2) Limited") AND inv:"Alexander Preston" 第 1 页

1.

发明授权
2,3-disubstituted 1-acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors 有权

公开(公告)号：US11478478B2

公开(公告)日：2022-10-25

申请号：US16735956

申请日：2020-01-07

申请人： GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED

发明人： Dominique Amans , Stephen John Atkinson , Lee Andrew Harrison , David Jonathan Hirst , Robert Peter Law , Matthew Lindon , Alexander Preston , Jonathan Thomas Seal , Christopher Roland Wellaway

IPC分类号： A61K31/506 , C07D401/14 , C07D405/14 , C07D413/14 , C07D215/227 , C07D215/46 , C07D215/48 , C07D401/04 , C07D401/12 , C07D405/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D471/08 , C07D487/08 , C07D498/04 , A61P29/00 , A61P37/00 , A61P31/12 , A61P35/00 , C07D215/44 , A61K31/4375 , A61K31/4706 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/5377 , A61K31/5386 , C07D498/08

摘要： The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

2.

发明申请
2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS 有权

公开(公告)号：US20230040299A1

公开(公告)日：2023-02-09

申请号：US17895273

申请日：2022-08-25

申请人： GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED

发明人： Dominique Amans , Stephen John Atkinson , Lee Andrew Harrison , David Jonathan Hirst , Robert Peter Law , Matthew Lindon , Alexander Preston , Jonathan Thomas Seal , Christopher Roland Wellaway

IPC分类号： A61K31/506 , C07D401/14 , C07D405/14 , C07D413/14 , C07D215/227 , C07D215/46 , C07D215/48 , C07D401/04 , C07D401/12 , C07D405/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D471/08 , C07D487/08 , C07D498/04 , A61P29/00 , A61P37/00 , A61P31/12 , A61P35/00 , C07D215/44 , A61K31/4375 , A61K31/4706 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/5377 , A61K31/5386 , C07D498/08

摘要： The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

3.

发明申请
2,3-DISUBSTITUTED 1-ACYL-4-AMINO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS BROMODOMAIN INHIBITORS 有权

公开(公告)号：US20210046073A1

公开(公告)日：2021-02-18

申请号：US16735956

申请日：2020-01-07

申请人： GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED

发明人： Dominique Amans , Stephen John Atkinson , Lee Andrew Harrison , David Jonathan Hirst , Robert Peter Law , Matthew Lindon , Alexander Preston , Jonathan Thomas Seal , Christopher Roland Wellaway

IPC分类号： A61K31/506 , A61P35/00 , A61P31/12 , A61P37/00 , A61P29/00 , C07D498/08 , A61K31/5386 , A61K31/5377 , A61K31/497 , A61K31/496 , A61K31/4709 , A61K31/4706 , A61K31/4375 , C07D215/44 , C07D498/04 , C07D487/08 , C07D471/08 , C07D471/04 , C07D417/14 , C07D417/12 , C07D413/12 , C07D413/04 , C07D409/14 , C07D409/12 , C07D405/04 , C07D401/12 , C07D401/04 , C07D215/48 , C07D215/46 , C07D215/227 , C07D413/14 , C07D405/14 , C07D401/14

摘要： The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

4.

发明授权
2,3-disubstituted 1-acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors 有权

公开(公告)号：US10583139B2

公开(公告)日：2020-03-10

申请号：US16016955

申请日：2018-06-25

申请人： GlaxoSmithKline Intellectual Property (No.2) Limited

发明人： Dominique Amans , Stephen John Atkinson , Lee Andrew Harrison , David Jonathan Hirst , Robert Peter Law , Matthew Lindon , Alexander Preston , Jonathan Thomas Seal , Christopher Roland Wellaway

IPC分类号： A61K31/506 , A61K31/497 , C07D401/14 , A61K31/4709 , A61K31/496 , C07D498/08 , A61K31/5377 , A61K31/5386 , A61K31/4375 , A61K31/4706 , C07D498/04 , C07D487/08 , C07D471/08 , C07D471/04 , C07D471/14 , C07D471/12 , C07D413/12 , C07D405/14 , C07D413/14 , C07D215/227 , C07D215/46 , C07D215/48 , C07D401/04 , C07D401/12 , C07D405/04 , C07D409/12 , C07D409/14 , C07D413/04 , C07D417/12 , C07D417/14 , C07D215/44

摘要： The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.

5.

发明授权
2,3-disubstituted 1 -acyl-4-amino-1,2,3,4-tetrahydroquinoline derivatives and their use as bromodomain inhibitors 有权

公开(公告)号：US10034881B2

公开(公告)日：2018-07-31

申请号：US15466925

申请日：2017-03-23

申请人： GlaxoSmithKline Intellectual Property (No.2) Limited

发明人： Dominique Amans , Stephen John Atkinson , Lee Andrew Harrison , David Jonathan Hirst , Robert Peter Law , Matthew Lindon , Alexander Preston , Jonathan Thomas Seal , Christopher Roland Wellaway

IPC分类号： A61K31/506

CPC分类号： A61K31/506 , A61K31/4375 , A61K31/4706 , A61K31/4709 , A61K31/496 , A61K31/497 , A61K31/5377 , A61K31/5386 , A61P29/00 , A61P31/12 , A61P35/00 , A61P37/00 , C07D215/227 , C07D215/44 , C07D215/46 , C07D215/48 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/04 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D471/08 , C07D487/08 , C07D498/04 , C07D498/08

摘要： The present invention relates to novel compounds, pharmaceutical compositions containing such compounds and to their use in therapy.