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    Systems and methods for the automated pre-treatment and processing of biological samples
    2.
    发明申请
    Systems and methods for the automated pre-treatment and processing of biological samples 有权
    用于生物样品自动预处理和处理的系统和方法

    公开(公告)号：US20070010911A1

    公开(公告)日：2007-01-11

    申请号：US11338522

    申请日：2006-01-23

    申请人： Gordon Feingold ,  James Gilmartin ,  Mark Holbrook ,  John Favuzzi ,  Marc Key

    发明人： Gordon Feingold ,  James Gilmartin ,  Mark Holbrook ,  John Favuzzi ,  Marc Key

    IPC分类号： G06F19/00

    CPC分类号： G01N1/312 ,  G01N35/0092 ,  G01N35/0099 ,  G06F19/00 ,  G16H40/63 ,  Y10T436/11 ,  Y10T436/110833 ,  Y10T436/111666 ,  Y10T436/112499 ,  Y10T436/114998 ,  Y10T436/25 ,  Y10T436/2575

    摘要： Systems and methods in accordance with embodiments of the present invention allow for the automatic control and scheduling of a staining apparatus for biological samples on slides present within the apparatus. In some embodiments, the actions of a robot coupled to the staining apparatus, which performs some of the staining tasks on the individual slides in accordance with their respective protocols, may be prioritized and scheduled. In some embodiments, the scheduling may result in increasing or maximizing the throughput of slides. In some embodiments, robot scheduling ensures that the individual slides are processed substantially within the tolerances specified by their respective protocols. In some embodiments, the robot scheduler may respond to spontaneous user actions and adaptively schedule or re-schedule robot actions.

    摘要翻译： 根据本发明的实施例的系统和方法允许对存在于装置内的载玻片上的生物样品的染色装置进行自动控制和调度。 在一些实施例中，可以对与染色设备耦合的机器人的动作进行优先级排列，所述机器人根据各自的协议在各个幻灯片上执行一些染色任务。 在一些实施例中，调度可导致增加或最大化幻灯片的吞吐量。 在一些实施例中，机器人调度确保各个滑块基本上在其各自协议规定的公差内被处理。 在一些实施例中，机器人调度器可以响应自发的用户动作并且自适应地调度或重新调度机器人动作。

    Pyridonazo dyes and inks containing them
    4.
    发明授权
    Pyridonazo dyes and inks containing them 失效
    吡啶并氮杂染料和含有它们的油墨

    公开(公告)号：US06406526B1

    公开(公告)日：2002-06-18

    申请号：US09446413

    申请日：2000-03-09

    申请人： Barry Huston Meyrick ,  Mark Holbrook ,  Roy Bradbury

    发明人： Barry Huston Meyrick ,  Mark Holbrook ,  Roy Bradbury

    IPC分类号： C09D1102

    CPC分类号： C09D11/328 ,  C09B29/363

    摘要： A dye of Formula (1) or tautomer thereof: wherein: A is di-, tri-, tetra-, or penta-substituted phenyl; R1 is methyl; R2 is H, CN, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, aryl, substituted aryl or a carbonamido group; and R3 is 5- or 6-membered ring comprising carbon atoms and one or two O, N and/or S atoms, wherein the ring may be substituted are useful as a component for inks, especially, ink jet printing inks and provide good storage stability, and high color strength. Inks containing the dye of formula (1) with a water dissipatable polymer in an aqueous medium produce images having high light-fastness and water-fastness and may be printed on various substrates, including paper, overhead transparencies and textiles, and may be applied using ink jet printers.

    摘要翻译： 式（1）的染料或其互变异构体：其中：A是二，三，四或五取代的苯基; R 1是甲基; R 2是H，CN，烷基，取代的烷基，烯基，取代的链烯基， 炔基，取代的炔基，芳基，取代的芳基或碳酰氨基; 和R 3是包含碳原子和一个或两个O，N和/或S原子的5-或6-元环，其中所述环可以被取代，可用作油墨的组分，特别是喷墨印刷油墨，并且提供良好的储存稳定性 ，色彩强度高。 在水性介质中含有具有可分散水分子的式（1）染料的油墨产生具有高耐光牢度和耐水性的图像，并且可以印刷在各种基材上，包括纸，高架透明胶片和纺织品，并且可以使用 喷墨打印机。

    Ink compositions
    5.
    发明授权
    Ink compositions 失效
    油墨组合物

    公开(公告)号：US06187084B1

    公开(公告)日：2001-02-13

    申请号：US09277378

    申请日：1999-03-29

    申请人： Roy Bradbury ,  Clive Moscrop ,  Barry Huston Meyrick ,  Mark Holbrook

    发明人： Roy Bradbury ,  Clive Moscrop ,  Barry Huston Meyrick ,  Mark Holbrook

    IPC分类号： C09D1102

    CPC分类号： C09D11/328 ,  C09B29/0081 ,  C09B29/0811

    摘要： An ink comprising water, a water-dissipatable polymer and one or more dyes of Formula (1): wherein: R1 is H or a substituent; R2 and R3 are each independently optionally substituted alkyl, aryl or aralkyl, or R2 and R3 together with the carbon atom to which they are attached form an optionally substituted ring; R4 is H or optionally substituted alkyl, aryl or aralkyl; and D is an optionally substituted arylene group. Also claimed are the dyes of Formula (1), ink jet printing processes and cartridges containing the inks.

    摘要翻译： 一种包含水，可水分散的聚合物和一种或多种式（1）的染料的油墨：其中：R 1是H或取代基; R 2和R 3各自独立地是任意取代的烷基，芳基或芳烷基，或R 2和R 3与 它们所连接的碳原子形成任选取代的环; R 4是H或任选取代的烷基，芳基或芳烷基; 且D为任选取代的亚芳基。 还要求保护的是式（1）的染料，喷墨印刷方法和含有这些油墨的墨盒。

    Compositions and processes
    6.
    发明授权
    Compositions and processes 有权
    组合和过程

    公开(公告)号：US07314274B2

    公开(公告)日：2008-01-01

    申请号：US10509936

    申请日：2003-02-27

    申请人： John O'Donnell ,  Kevin Johnson ,  Mark Holbrook ,  Stephen George Yeates ,  Tom Annable

    发明人： John O'Donnell ,  Kevin Johnson ,  Mark Holbrook ,  Stephen George Yeates ,  Tom Annable

    IPC分类号： G01D11/00

    CPC分类号： B41M5/0017 ,  B41M7/0018

    摘要： An ink-jet printing process comprising the steps (a) and (b) in any order or simultaneously: (a) applying an ink to a substrate by means of an ink-jet printer to form an image on a substrate; and (b) applying to the substrate a fixing composition comprising a liquid medium and a polymer containing a plurality of monoguanide and/or biguanide groups by means of an ink jet printer; characterised in that in the fixing composition has a chloride concentration less than 400 ppm by weight.

    摘要翻译： 一种包括步骤（a）和（b）的喷墨打印方法，其任意顺序或同时进行：（a）借助于喷墨打印机将油墨施加到基底上以在基底上形成图像; 和（b）通过喷墨打印机将包含液体介质和含有多个单胍类和/或双胍类基团的聚合物的定影组合物施加到基底上; 其特征在于，在定影组合物中氯化物浓度小于400重量ppm。

    Pyridonazo dyes and inks containing them
    7.
    发明授权
    Pyridonazo dyes and inks containing them 失效
    吡啶并氮杂染料和含有它们的油墨

    公开(公告)号：US06303763B1

    公开(公告)日：2001-10-16

    申请号：US09446384

    申请日：1999-12-21

    申请人： Barry Huston Meyrick ,  Mark Holbrook ,  Roy Bradbury

    发明人： Barry Huston Meyrick ,  Mark Holbrook ,  Roy Bradbury

    IPC分类号： C09B2942

    CPC分类号： C09D11/328 ,  C09B29/363

    摘要： Dyes of the Formula (1) and tautomers thereof: wherein: A is optionally substituted phenyl; R1 is H, optionally substituted alkyl, optionally substituted alkenyl or optionally substituted alkynyl; R2 is H, CN, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl or a carbonamido group; and R3 is an optionally substituted 5- or 6-membered ring; provided that R1 is not methyl. Also claimed are inks comprising a dye of the Formula (1) an aqueous medium and a water-dissipatable polymer; a method of ink jet printing using the inks; and a substrate printed with an ink according to the invention.

    摘要翻译： 式（1）的染料及其互变异构体：其中：A为任选取代的苯基; R 1为H，任选取代的烷基，任选取代的烯基或任选取代的炔基; R 2为H，CN，任选取代的烷基，任选取代的烯基， 取代的炔基，任选取代的芳基或碳酰氨基; 和R 3是任选取代的5或6元环; 条件是R 1不是甲基。还要求的是包含式（1）的染料，水性介质和可水分散的聚合物的油墨; 使用该油墨的喷墨印刷方法; 以及印刷有根据本发明的油墨的基材。

    Dispersion
    10.
    发明授权
    Dispersion 失效
    分散

    公开(公告)号：US5494511A

    公开(公告)日：1996-02-27

    申请号：US12435

    申请日：1993-02-02

    申请人： Mark Holbrook

    发明人： Mark Holbrook

    IPC分类号： B01F17/42 ,  B01J13/00 ,  C09B67/46 ,  C09C3/08 ,  C09C3/10 ,  C09D5/00 ,  C09D5/02 ,  C09D7/06 ,  C09D7/12 ,  C09D11/02 ,  C09D17/00 ,  C09D11/10

    CPC分类号： C09D11/03 ,  C09D17/001 ,  C09D5/027

    摘要： A dispersion of a finely divided pigment in a composition of water, one or more water-compatible resins and, as dispersant, a polycyclic aromatic compound having a water-solubilising poly(C.sub.2-4 -alkyleneoxy) chain containing from 3 to 50 alkyleneoxy groups, characterised in that the dispersion contains from 3% to 30% by weight or resin with respect to the total weight of water and resin in the dispersion. The dispersion is suitable for the preparation of water-borne paint and inks.

    摘要翻译： 精细分散的颜料在水，一种或多种水相容性树脂的组合物中的分散体，以及作为分散剂的具有含有3至50个亚烷基氧基的水溶性聚（C 2-4亚烷基氧基）链的多环芳族化合物 其特征在于，相对于分散体中的水和树脂的总重量，分散体含有3重量％至30重量％或树脂。 该分散体适用于制备水性油漆和油墨。