公开(公告)号：US12110293B2

公开(公告)日：2024-10-08

申请号：US17152930

申请日：2021-01-20

申请人： GRÜNENTHAL GMBH

发明人： Florian Jakob ,  Jo Alen ,  Simon Lucas ,  Tobias Craan ,  Ingo Konetzki ,  Achim Kless ,  Stefan Schunk ,  Paul Ratcliffe ,  Sebastian Wachten ,  Simon Cruwys

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： The present invention relates to compounds according to general formula (I)




which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

公开(公告)号：US11981677B2

公开(公告)日：2024-05-14

申请号：US17171520

申请日：2021-02-09

申请人： Grünenthal GmbH

发明人： Florian Jakob ,  Jo Alen ,  Simon Lucas ,  Tobias Craan ,  Ingo Konetzki ,  Achim Kless ,  Stefan Schunk ,  Paul Ratcliffe ,  Sebastian Wachten ,  Simon Cruwys

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： The present invention relates to compounds according to general formula (I)




which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

公开(公告)号：US10981918B2

公开(公告)日：2021-04-20

申请号：US16517080

申请日：2019-07-19

申请人： Grünenthal GmbH

发明人： Florian Jakob ,  Jo Alen ,  Simon Lucas ,  Tobias Craan ,  Ingo Konetzki ,  Achim Kless ,  Stefan Schunk ,  Paul Ratcliffe ,  Sebastian Wachten ,  Simon Cruwys

IPC分类号： C07D487/04

摘要： The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.