-
1.发明申请公开(公告)号：US20150290203A1
公开(公告)日：2015-10-15
申请号：US14434943
申请日：2013-10-11
申请人： GRÜNENTHAL GMBH
IPC分类号： A61K31/5377 , A61K31/44 , A61K31/47
CPC分类号： A61K31/5377 , A61K31/44 , A61K31/47 , C07D213/82 , C07D215/48
摘要： The invention relates to certain compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders that are, at least partially, mediated by TSPO activity.
摘要翻译： 本发明涉及用于治疗和/或预防至少部分由TSPO活性介导的疾病和/或病症的某些化合物。
-
公开(公告)号：US10981918B2
公开(公告)日：2021-04-20
申请号：US16517080
申请日：2019-07-19
申请人： Grünenthal GmbH
发明人： Florian Jakob , Jo Alen , Simon Lucas , Tobias Craan , Ingo Konetzki , Achim Kless , Stefan Schunk , Paul Ratcliffe , Sebastian Wachten , Simon Cruwys
IPC分类号： C07D487/04
摘要： The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.
-
公开(公告)号：US09284286B2
公开(公告)日：2016-03-15
申请号：US14091373
申请日：2013-11-27
申请人： GRÜNENTHAL GMBH
IPC分类号： C07D277/56 , C07C323/62 , C07D495/04 , C07D471/04 , C07D213/82 , C07D239/38 , A61K31/44 , C07D237/24 , A61K31/4965 , C07D241/24 , A61K31/166 , A61K31/505 , A61K31/426 , A61K31/4436 , A61K31/50 , C07D213/81 , C07D409/12
CPC分类号： C07D277/56 , A61K31/166 , A61K31/426 , A61K31/44 , A61K31/4436 , A61K31/4965 , A61K31/50 , A61K31/505 , C07C323/62 , C07D213/81 , C07D213/82 , C07D237/24 , C07D239/38 , C07D241/24 , C07D409/12 , C07D471/04 , C07D495/04
摘要： The invention relates to specific carboxamides, to processes for their preparation, to medicaments comprising these compounds and to the use of these compounds in the preparation of medicaments.
摘要翻译： 本发明涉及特定的甲酰胺，其制备方法，包含这些化合物的药物以及这些化合物在制备药物中的用途。
-
公开(公告)号：US09278103B2
公开(公告)日：2016-03-08
申请号：US14230572
申请日：2014-03-31
申请人： Grünenthal GmbH
发明人： Sven Kühnert , Gregor Bahrenberg , Achim Kless , Wolfgang Schröder , Simon Lucas
IPC分类号： A61K31/5377 , C07D413/04 , A61K31/541 , C07D213/82 , C07D401/04 , C07D401/14 , C07D405/12 , C07D413/14 , A61K31/455 , C07D401/12 , C07D417/04
CPC分类号： A61K31/541 , A61K31/455 , A61K31/5377 , C07D213/82 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/12 , C07D413/04 , C07D413/14 , C07D417/04
摘要： Substituted 6-amino-nicotinamides, pharmaceutical compositions containing these compounds and also use of these compounds in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
-
公开(公告)号：US20170273970A1
公开(公告)日：2017-09-28
申请号：US15622292
申请日：2017-06-14
申请人： GRÜNENTHAL GMBH
IPC分类号： A61K31/47
CPC分类号： A61K31/47 , A61K31/4704
摘要： The invention relates to certain compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders that are, at least partially, mediated by TSPO activity.
-
公开(公告)号：US09248122B2
公开(公告)日：2016-02-02
申请号：US14091395
申请日：2013-11-27
申请人： GRÜNENTHAL GMBH
IPC分类号： A61K31/4375 , C07D471/04 , C07D495/04 , A61K31/4365 , A61K45/06
CPC分类号： A61K31/4375 , A61K31/4365 , A61K45/06 , C07D471/04 , C07D495/04
摘要： The invention relates to substituted heteroquinoline-3-carboxamides, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.
摘要翻译： 本发明涉及取代的杂喹啉-3-甲酰胺，含有这些化合物的药物组合物以及用于治疗和/或预防疼痛和其它疾病和/或病症的这些化合物。
-
公开(公告)号：US12110293B2
公开(公告)日：2024-10-08
申请号：US17152930
申请日：2021-01-20
申请人： GRÜNENTHAL GMBH
发明人： Florian Jakob , Jo Alen , Simon Lucas , Tobias Craan , Ingo Konetzki , Achim Kless , Stefan Schunk , Paul Ratcliffe , Sebastian Wachten , Simon Cruwys
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates to compounds according to general formula (I)
which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.-
公开(公告)号：US11981677B2
公开(公告)日：2024-05-14
申请号：US17171520
申请日：2021-02-09
申请人： Grünenthal GmbH
发明人： Florian Jakob , Jo Alen , Simon Lucas , Tobias Craan , Ingo Konetzki , Achim Kless , Stefan Schunk , Paul Ratcliffe , Sebastian Wachten , Simon Cruwys
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates to compounds according to general formula (I)
which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.-
公开(公告)号：US09775843B2
公开(公告)日：2017-10-03
申请号：US14434943
申请日：2013-10-11
申请人： GRÜNENTHAL GMBH
IPC分类号： A61K31/44 , A61K31/5377 , C07D213/82 , C07D215/48 , A61K31/47
CPC分类号： A61K31/5377 , A61K31/44 , A61K31/47 , C07D213/82 , C07D215/48
摘要： The invention relates to certain compounds for the use in the treatment and/or prophylaxis of diseases and/or disorders that are, at least partially, mediated by TSPO activity.
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.023 秒)
