公开(公告)号：US20190185455A1

公开(公告)日：2019-06-20

申请号：US16223845

申请日：2018-12-18

Applicant: Gruenenthal GmbH

Inventor： Florian JAKOB ,  Jo ALEN ,  Sebastian KRÜGER ,  Markus SCHADE ,  Daniela FRIEBE ,  Stephanie HENNEN

IPC: C07D401/14 ,  C07D403/14 ,  C07D417/14 ,  C07D405/14 ,  A61P25/00 ,  A61P29/00

CPC classification number: C07D401/14 ,  A61P11/06 ,  A61P19/02 ,  A61P25/00 ,  A61P29/00 ,  C07D403/14 ,  C07D405/14 ,  C07D413/14 ,  C07D417/14

Abstract: The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

公开(公告)号：US20190185470A1

公开(公告)日：2019-06-20

申请号：US16223925

申请日：2018-12-18

Applicant: Gruenenthal GmbH

Inventor： Florian JAKOB ,  Jo ALEN ,  Sebastian KRÜGER ,  Markus SCHADE ,  Daniela FRIEBE ,  Stephanie HENNEN

IPC: C07D471/04 ,  C07D409/14 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14 ,  C07D401/14 ,  C07D405/14 ,  C07D403/04 ,  A61P29/00

CPC classification number: C07D471/04 ,  A61P11/06 ,  A61P19/02 ,  A61P29/00 ,  C07D401/14 ,  C07D403/04 ,  C07D403/14 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14

Abstract: The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

公开(公告)号：US20200223840A1

公开(公告)日：2020-07-16

申请号：US16740735

申请日：2020-01-13

Applicant: Gruenenthal GMBH

Inventor： Florian JAKOB ,  Jo ALEN ,  Sebastian KRÜGER ,  Daniela FRIEBE ,  Stephanie HENNEN ,  Philipp BARBIE

IPC: C07D417/14 ,  C07D403/10 ,  C07D471/04 ,  C07D409/14 ,  C07D403/14 ,  C07D413/14 ,  C07D401/14

Abstract: The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.