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1.发明申请Use Of A Type III Restriction Enzyme To Isolate Identification Tags Comprising More Than 25 Nucleotides 审中-公开使用III型限制酶来分离包含多于25个核苷酸的鉴定标签公开(公告)号：US20080008993A1
公开(公告)日：2008-01-10
申请号：US10556030
申请日：2003-05-09
申请人： Guenter Kahl , Peter Winter , Detlev Krueger , Stefanie Reich , Hideo Matsumura , Ryohei Terauchi
发明人： Guenter Kahl , Peter Winter , Detlev Krueger , Stefanie Reich , Hideo Matsumura , Ryohei Terauchi
CPC分类号： C12Q1/6809 , C12Q1/6837 , C12Q2539/103 , C12Q2525/204 , C12Q2521/301 , C12Q2545/114
摘要： The type III restriction enzyme EcoP15I is used to isolate from cDNA of an expressed gene a tag comprising more than 25 nucleotides and capable of identifying the expressed gene, wherein the 3′ end of the tag is defined by a cleavage site of the type III restriction enzyme and the 5′ end of the tag is defined by the cleavage site of another restriction enzyme that is closest to the 3′ end of the cDNA of the expressed gene. The tag of the invention allows accurate quantitative gene expression analysis and rapid gene expression profiling in any organism for which no expressed sequence tag (EST) database is available.
摘要翻译： III型限制酶EcoP15I用于从表达基因的cDNA分离包含多于25个核苷酸并且能够鉴定表达基因的标签，其中标签的3'末端由III型限制酶切割位点 酶和标签的5'末端由最接近表达基因的cDNA的3'末端的另一限制酶的切割位点定义。 本发明的标签允许在没有表达序列标签（EST）数据库的任何生物体中进行准确的定量基因表达分析和快速的基因表达谱。
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2.发明申请Proteaseome inhibitors for the treatment of herpesviridae infected individuals 审中-公开用于治疗疱疹病毒科感染个体的蛋白酶抑制剂公开(公告)号：US20050171022A1
公开(公告)日：2005-08-04
申请号：US10520150
申请日：2003-07-02
摘要： The present invention relates to the use of a substance or composition comprising one or more proteasome inhibitors for the manufacture of a medicament for the treatment of an individual infected with a virus selected from the group comprising varicella zoster virus, human cytomegalovirus, human herpesvirus 6 and 7 and Epstein-Barr virus and Karposi's sarcoma herpesvirus. The invention further relates to methods of treatment of individuals infected with a virus selected from the group comprising varicella zoster virus, human cytomegalovirus, human herpesvirus 6 and 7 and Epstein-Barr virus and Karposi's sarcoma herpesvirus.
摘要翻译： 本发明涉及包含一种或多种蛋白酶体抑制剂的物质或组合物在制备用于治疗感染病毒的个体的药物的用途，所述病毒选自水痘带状疱疹病毒，人巨细胞病毒，人疱疹病毒6和 7和爱泼斯坦 - 巴尔病毒和卡洛斯氏肉瘤疱疹病毒。 本发明还涉及治疗感染病毒的个体的方法，所述病毒选自水痘带状疱疹病毒，人巨细胞病毒，人疱疹病毒6和7以及爱泼斯坦 - 巴尔病毒和卡波西氏肉瘤疱疹病毒。
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3.发明申请Proteaseome inhibitors for the treatment of herpesviridae infected individuals 审中-公开用于治疗疱疹病毒科感染个体的蛋白酶抑制剂公开(公告)号：US20070042967A1
公开(公告)日：2007-02-22
申请号：US11528361
申请日：2006-09-28
摘要： The present invention relates to the use of a substance or composition comprising one or more proteasome inhibitors for the manufacture of a medicament for the treatment of an individual infected with a virus selected from the group comprising varicella zoster virus, human cytomegalovirus, human herpesvirus 6 and 7 and Epstein-Barr virus and Karposi's sarcoma herpesvirus. The invention further relates to methods of treatment of individuals infected with a virus selected from the group comprising varicella zoster virus, human cytomegalovirus, human herpesvirus 6 and 7 and Epstein-Barr virus and Karposi's sarcoma herpesvirus.
摘要翻译： 本发明涉及包含一种或多种蛋白酶体抑制剂的物质或组合物在制备用于治疗感染病毒的个体的药物的用途，所述病毒选自水痘带状疱疹病毒，人巨细胞病毒，人疱疹病毒6和 7和爱泼斯坦 - 巴尔病毒和卡洛斯氏肉瘤疱疹病毒。 本发明还涉及治疗感染病毒的个体的方法，所述病毒选自水痘带状疱疹病毒，人巨细胞病毒，人疱疹病毒6和7以及爱泼斯坦 - 巴尔病毒和卡波西氏肉瘤疱疹病毒。
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