公开(公告)号：US20060207058A1

公开(公告)日：2006-09-21

申请号：US10543235

申请日：2004-01-20

申请人： Gundolf Heinrichs ,  Ute Kruger ,  Peter Hoffmann

发明人： Gundolf Heinrichs ,  Ute Kruger ,  Peter Hoffmann

IPC分类号： E05F5/02

CPC分类号： E05C17/203 ,  Y10T16/5995 ,  Y10T16/61 ,  Y10T16/625 ,  Y10T16/629

摘要： A door check is provided comprising a housing (2) that can be fixed to a door or door frame and is provided with a first housing half (3) and a second housing half (4) which can be connected to each other, and a stay bar (24) that penetrates an opening (23) within the housing (2) and is pivotally mounted on the door frame or door, the housing (2) and the stay bar (24) not being fixed to/mounted on the same part. The first housing half (3) and the second housing half (4) respectively delimit only one section of the circumference of the opening (23). In order to create a door check that allows reliable and secure retaining and can be produced at low cost, a braking member (13) which is biased in the direction of the stay bar (24) by means of a spring element (20) is disposed in at least one of the two housing halves (3, 4).

摘要翻译： 提供了一种门检查件，其包括可固定到门或门框架的壳体（2），并且设置有可彼此连接的第一壳体半部（3）和第二壳体半部（4），并且 支撑杆（24），其穿过壳体（2）内的开口（23）并且枢转地安装在门框或门上，壳体（2）和撑杆（24）不被固定到/安装在其上 部分。 第一壳体半部（3）和第二壳体半部（4）分别限定开口（23）的圆周的仅一个部分。 为了产生允许可靠且牢固地保持并且可以以低成本生产的门检查，通过弹簧元件（20）沿着拉杆（24）的方向偏置的制动构件（13） 设置在两个壳体半部（3,4）中的至少一个中。

公开(公告)号：US20060059657A1

公开(公告)日：2006-03-23

申请号：US10542510

申请日：2004-01-20

申请人： Gundolf Heinrichs ,  Peter Hoffmann ,  Ute Kruger

发明人： Gundolf Heinrichs ,  Peter Hoffmann ,  Ute Kruger

IPC分类号： E05F5/06

CPC分类号： E05C17/203 ,  Y10T16/625 ,  Y10T16/6295

摘要： A door arrester is provided which comprises a housing (2), fastened on either the door or the door frame, a retaining rod (24), extending through an opening (23) in the housing (2) and fastened on the respective other part of door and door frame so as to be pivoted, at least one brake member (14) pretensioned in the direction towards the retaining rod (24) and having a peripheral surface (16) that is received in the housing (2) so as to be axially displaceable, and at least two fastening bores (9) oriented at an angle to the locating plane of the housing (2). An aim of the invention is to improve the generic door arrester so that it reliably and securely holds the door while being inexpensive to produce. For this purpose, one fastening bore (9) each is disposed on both sides of the principle planes which are perpendicular to the locating plane of the housing (2).

摘要翻译： 提供了一种门禁器，其包括紧固在门或门框架上的壳体（2），延伸穿过壳体（2）中的开口（23）并固定在相应的另一部分上的保持杆（24） 门框和框架以便枢转;至少一个制动构件（14），其沿朝向保持杆（24）的方向预张紧并且具有容纳在壳体（2）中的外围表面（16），从而 以及至少两个与壳体（2）的定位平面成一角度定向的紧固孔（9）。 本发明的目的是改进通用门禁器，使其可靠且牢固地保持门，同时制造成本低廉。 为此，一个紧固孔（9）分别设置在垂直于壳体（2）的定位平面的主平面的两侧。

公开(公告)号：US20090010871A1

公开(公告)日：2009-01-08

申请号：US12280499

申请日：2007-02-21

申请人： Christoph Erbacher ,  Ute Kruger

发明人： Christoph Erbacher ,  Ute Kruger

IPC分类号： A61K31/77 ,  C12N15/00 ,  A61K35/12 ,  C08G59/02

CPC分类号： A61K48/00 ,  A61K47/59 ,  C07H21/00 ,  C12N15/87 ,  Y10S977/702

摘要： The invention relates to a method for incorporation of a biomolecule into a cell including the method steps: i) production of a complex from a biomolecule, preferably a nucleic acid and a polymer which may be obtained by reaction of an amine monomer having at least two amine groups with an epoxide monomer having at least two epoxide groups and ii) incorporation of the biomolecule into a cell bx bringing the cell into contact with the complex. The invention further relates to the transformed cell obtained by said method, the use of a particular polymer for incorporation of a biomolecule into a cell, a kit for incorporation of a biomolecule into a cell, the use of said kit, a complex made from a biomolecule and a polymer, a therapeutic composition, the use of a complex of a biomolecule and a polymer for therapeutic treatment of the human or animal being and a method for treatment of a disease by means of gene therapy.

摘要翻译： 本发明涉及用于将生物分子结合到细胞中的方法，包括以下步骤：i）从生物分子，优选核酸和聚合物制备复合物，所述核酸和聚合物可以通过具有至少两个 胺基与具有至少两个环氧基团的环氧化物单体，和ii）将生物分子掺入到使细胞与复合物接触的细胞bx中。 本发明还涉及通过所述方法获得的转化细胞，将特定聚合物用于将生物分子并入细胞中的用途，用于将生物分子并入细胞的试剂盒，所述试剂盒的使用，由 生物分子和聚合物，治疗组合物，生物分子和聚合物的复合物在人或动物的治疗中的用途以及通过基因治疗治疗疾病的方法。