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公开(公告)号:US08642624B2
公开(公告)日:2014-02-04
申请号:US13297213
申请日:2011-11-15
申请人: Guoqing Chen , Jeffrey A. Adams , Jean E. Bemis , Shon Booker , Guolin Cai , Lucian V. DiPietro , Celia Dominguez , Daniel Elbaum , Julie Germain , Stephanie Geuns-Meyer , Michael K. Handley , Qi Huang , Joseph L. Kim , Tae-Seong Kim , Alexander S. Kiselyov , Xiaohu Ouyang , Vinod F. Patel , Leon M. Smith , Markian M. Stec , Andrew Tasker , Ning Xi , Shimin Xu , Chester Chenguang Yuan , Michael D. Croghan
发明人: Guoqing Chen , Jeffrey A. Adams , Jean E. Bemis , Shon Booker , Guolin Cai , Lucian V. DiPietro , Celia Dominguez , Daniel Elbaum , Julie Germain , Stephanie Geuns-Meyer , Michael K. Handley , Qi Huang , Joseph L. Kim , Tae-Seong Kim , Alexander S. Kiselyov , Xiaohu Ouyang , Vinod F. Patel , Leon M. Smith , Markian M. Stec , Andrew Tasker , Ning Xi , Shimin Xu , Chester Chenguang Yuan , Michael D. Croghan
IPC分类号: A01N43/40 , A61K31/44 , A01N43/38 , A61K31/40 , A61K31/405
CPC分类号: C07D213/82 , A61K31/443 , A61K31/4439 , A61K31/444 , A61K31/4545 , A61K31/4709 , A61K31/4725 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/538 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/00 , C07D409/04 , C07D409/12 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04
摘要: Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like.
摘要翻译: 所选择的杂环化合物对于预防和治疗诸如血管生成介导的疾病等疾病是有效的。 本发明包括新型化合物,类似物,前药及其药学上可接受的衍生物,用于预防和治疗疾病和其它疾病或涉及癌症等的病症的药物组合物和方法。