Optical sensor using an immunological reaction and a fluorescent marker
    1.
    发明授权
    Optical sensor using an immunological reaction and a fluorescent marker 失效
    光学传感器使用免疫反应和荧光标记

    公开(公告)号:US06312961B1

    公开(公告)日:2001-11-06

    申请号:US09317273

    申请日:1999-05-24

    申请人: Guy Voirin Rino Kunz

    发明人: Guy Voirin Rino Kunz

    IPC分类号: G01N33543

    摘要: A biosensor comprises a waveguide into which light is coupled by a diffraction grating. The sample to be analyzed is placed on a reaction region in which a component of the immunological reaction is provided, for example antibodies or antigens. Fluorescence is excited on the surface of the waveguide because of the presence of a marker for example, a labelled antigen or antibody. Fluorescence is decoupled from the waveguide by the coupling diffraction grating or another diffraction grating. The waveguide is made of a material emitting light when it is excited by the marker excitation beam. This latter emission has a peak wavelength different from that of the emission radiation due to the marker used in the immunological reaction. Waveguide material fluorescence emission provides a reference during measurement.

    摘要翻译: 生物传感器包括通过衍射光栅耦合光的波导。 将要分析的样品放置在其中提供免疫反应的组分的反应区域,例如抗体或抗原。 由于存在标记例如标记的抗原或抗体,波导表面上的荧光被激发。 荧光通过耦合衍射光栅或另一衍射光栅与波导解耦。 波导由被标记激发光束激发时发光的材料制成。 由于在免疫反应中使用的标记,后一种发射具有与发射辐射不同的峰值波长。 波导材料荧光发射在测量过程中提供参考。

    FABRICATION PROCESS OF A MICROFABRICATED BLAZED GRATING
    2.
    发明申请
    FABRICATION PROCESS OF A MICROFABRICATED BLAZED GRATING 有权
    微晶玻璃烧结的制备工艺

    公开(公告)号:US20100220395A1

    公开(公告)日:2010-09-02

    申请号:US12161640

    申请日:2007-01-22

    IPC分类号: G02B5/18 G03F7/20

    摘要: A blazed grating is disclosed as well as mode hop-free tunable lasers and a process for fabricating gratings of this type. The grating lies in a general plane and includes a plurality of elongate beams carrying mutually parallel respective reflection surfaces spaced apart from one another with a predefined pitch, each of these reflection surfaces having a normal direction inclined at a grating angle α to the normal direction of the general plane. The grating includes a plurality of resilient suspension arms connected to the beams and intended to be fastened to a grating support. A first pair of comb electrodes is provided for applying a mechanical force to this assembly, being placed on a first side of the grating, along an axis transverse to the beams, and designed so as to allow the pitch of the grating to be modified in response to the application of the mechanical force.

    摘要翻译: 公开了一种闪耀的光栅以及无跳变可调激光器以及用于制造这种类型的光栅的工艺。 光栅位于通用平面中,并且包括多个细长梁,其承载相互平行的各自的反射表面,以预定的间距彼此间隔开,每个反射面具有沿与法线方向 一般飞机。 光栅包括连接到光束并且被固定到光栅支架上的多个弹性悬挂臂。 第一对梳状电极被设置用于沿着横向于梁的轴线向该组件施加机械力,该机械力被放置在光栅的第一侧上,并被设计成允许光栅的间距在 响应机械力的应用。

    Fabrication process of a microfabricated blazed grating
    3.
    发明授权
    Fabrication process of a microfabricated blazed grating 有权
    微加工闪光光栅的制作工艺

    公开(公告)号:US08465660B2

    公开(公告)日:2013-06-18

    申请号:US12161640

    申请日:2007-01-22

    摘要: A blazed grating is disclosed as well as mode hop-free tunable lasers and a process for fabricating gratings of this type. The grating lies in a general plane and includes a plurality of elongate beams carrying mutually parallel respective reflection surfaces spaced apart from one another with a predefined pitch, each of these reflection surfaces having a normal direction inclined at a grating angle α to the normal direction of the general plane. The grating includes a plurality of resilient suspension arms connected to the beams and intended to be fastened to a grating support. A first pair of comb electrodes is provided for applying a mechanical force to this assembly, being placed on a first side of the grating, along an axis transverse to the beams, and designed so as to allow the pitch of the grating to be modified in response to the application of the mechanical force.

    摘要翻译: 公开了一种闪耀的光栅以及无跳变可调激光器以及用于制造这种类型的光栅的工艺。 光栅位于通用平面中,并且包括多个细长梁,其承载相互平行的各自的反射表面,彼此以预定的间距彼此间隔开,每个反射面具有以与法线方向成α角的光栅角度倾斜的法线方向 一般飞机。 光栅包括连接到光束并且被固定到光栅支架上的多个弹性悬挂臂。 第一对梳状电极被设置用于沿着横向于梁的轴线向该组件施加机械力,该机械力被放置在光栅的第一侧上,并被设计成允许光栅的间距在 响应机械力的应用。

    Process and device for measuring light beams
    4.
    发明授权
    Process and device for measuring light beams 失效
    用于测量光束的过程和装置

    公开(公告)号:US5991480A

    公开(公告)日:1999-11-23

    申请号:US817993

    申请日:1997-06-23

    IPC分类号: G01J3/18 G02B6/34

    摘要: A light beam (6) is applied to a waveguide (3) in order to measure properties of the beam (6), e.g. the wavelength. According to the invention, the waveguide (3) has locally and/or time-varying resonances, e.g. by suitably designed grid couplers (4, 5). A light signal (7) is thus generated in the waveguide (3) as a direct measurement of the property to be measured and can be further processed by suitable means or evaluated. It is thus possible, for example, advantageously to produce a simple and inexpensive spectrometer.

    摘要翻译: PCT No.PCT / CH96 / 00275 Sec。 371日期:1997年6月23日 102(e)日期1997年6月23日PCT提交1996年8月7日PCT公布。 出版物WO97 / 09594 日期1997年3月18日为了测量光束(6)的性质,例如将光束(6)施加到波导(3)。 波长。 根据本发明,波导(3)具有局部和/或时变共振,例如。 通过适当设计的电网耦合器(4,5)。 因此,在波导(3)中产生光信号(7),作为要测量的性质的直接测量,并且可以通过合适的方法进一步处理或评估。 因此,有可能有利地生产简单且便宜的光谱仪。

    Tunable laser
    6.
    发明授权
    Tunable laser 有权
    可调谐激光

    公开(公告)号:US07826501B2

    公开(公告)日:2010-11-02

    申请号:US12176879

    申请日:2008-07-21

    IPC分类号: H01S3/10

    摘要: A mode hop-free tunable laser including a gain medium, a microfabricated blazed grating, defining an external cavity of a given length, the blazed grating lying in a general plane and including a plurality of elongate beams carrying mutually parallel respective reflection surfaces spaced apart from one another with a predefined pitch, and actuating elements designed so as to allow displacements of the assembly with respect to a grating support within a plane substantially parallel to the grating general plane, and including actuation elements designed so as to apply a stretching and a displacement of the assembly in a direction transverse to said reflection surfaces, the blazed grating being arranged relative to an incident light beam provided by the gain medium so that the incident light beam impinges on the reflection surfaces with a substantially normal incident angle.

    摘要翻译: 包括增益介质的模式跳跃可调谐激光器,限定给定长度的外部空腔的微型闪光光栅,所述闪耀的光栅位于总体平面中,并且包括多个细长光束,所述多个细长光束承载相互平行的各自的反射表面, 彼此具有预定的间距,以及致动元件,其被设计成允许组件相对于基本上平行于光栅总体平面的平面内的光栅支撑件移位,并且包括设计成施加拉伸和位移的致动元件 在相对于所述反射表面横向的方向上,所述闪耀的光栅相对于由增益介质提供的入射光束布置,使得入射光束以基本上正常的入射角度照射在反射表面上。

    Integrated-optical sensor and method for integrated-optically sensing a substance
    7.
    发明授权
    Integrated-optical sensor and method for integrated-optically sensing a substance 有权
    集成光学传感器和集成光学感测物质的方法

    公开(公告)号:US06429022B1

    公开(公告)日:2002-08-06

    申请号:US09510609

    申请日:2000-02-22

    IPC分类号: G01N2101

    CPC分类号: G01N21/7743

    摘要: The integrated-optical chemical and/or biochemical sensor comprises a resonant waveguide grating structure (1.1, 1.2, . . . ), e.g., a chirped grating. By illumination with incident light (21), a resonant electromagnetic field is excited in the grating structure (1.1, 1.2, . . . ). At least one parameter of the incident light, e.g., the angle of incidence (&thgr;1) or the wavelength (&lgr;1), is varied. Light (23) excident from the grating structure (1.1, 1.2, . . . ) is detected by detectors (4.1, 4.2, . . . ). Optionally, means for providing a feedback from the detectors (4.1, 4.2, . . . ) to the light sources may be provided, thus establishing a controlled closed-loop system. Hence independent simultaneous measurements in a multiple arrangement of such sensors (S1, S2, . . . ) is made possible. Moreover, a much higher density of sensors (S1, S2, . . . ) results.

    摘要翻译: 集成光学化学和/或生物化学传感器包括谐振波导光栅结构(1.1,1.2 ...),例如啁啾光栅。 通过用入射光(21)进行照明,在光栅结构(1.1,1.2 ...)中激发谐振电磁场。 入射光的至少一个参数,例如入射角(θ1)或波长(lambd1)变化。 通过检测器(4.1,4.2,...)检测从光栅结构(1.1,1.2,...)排出的光(23)。 可选地,可以提供用于提供来自检测器(4.1,4.2,...)到光源的反馈的装置,从而建立受控的闭环系统。 因此,可以在这种传感器(S1,S2,...)的多重布置中进行独立的同时测量。 而且,传感器密度要高得多(S1,S2,...)。