公开(公告)号：US20210077393A1

公开(公告)日：2021-03-18

申请号：US16975171

申请日：2019-02-19

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Toshihiro NAKANISHI ,  Yuko NAGASE ,  Shinya MATSUMURA ,  Yasuhisa KOSE

IPC: A61K9/06 ,  A61K31/196 ,  A61K47/38 ,  A61K47/22 ,  A61K47/18 ,  A61K47/10 ,  A61K47/14 ,  A61K47/26

Abstract: The present invention provides an emulsified gel composition comprising diclofenac sodium, water, a gelling agent, an antioxidant, and a surfactant having an HLB of 14 or more, in which the gelling agent is a nonionic water-soluble polymer.

公开(公告)号：US20220079879A1

公开(公告)日：2022-03-17

申请号：US17536295

申请日：2021-11-29

Applicant: HISAMITSU PHARMACEUTICAL CO., INC.

Inventor： Shinya MATSUMURA ,  Toshihiro NAKANISHI ,  Yasuhisa KOSE

IPC: A61K9/06 ,  A61K9/107 ,  A61K31/196 ,  A61K47/10 ,  A61K47/32 ,  A61K47/38 ,  A61K47/44

Abstract: The present invention provides an emulsified gel composition comprising a physiologically active substance, water, a gelling agent, an anti-peeling agent, and a surfactant having an HLB value of 18 to 20, in which the gelling agent is a nonionic water-soluble polymer, and the anti-peeling agent is one or more compounds selected from the group consisting of sucrose, sorbitol, polyethylene glycol, glycerin, a (meth)acrylic-based polymer compound, and a polyoxyethylene hydrogenated castor oil.