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公开(公告)号：US20160175262A1
公开(公告)日：2016-06-23
申请号：US14974288
申请日：2015-12-18
Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
Inventor： Keiichiro TSURUSHIMA , Yasuhisa KOSE , Takaaki YOSHINAGA
CPC classification number: A61K9/7061 , A61K31/618 , A61K47/14 , A61K47/26
Abstract: A gel patch includes a base fabric, an adhesive layer, and a release liner in this order, wherein the adhesive layer contains a physiologically active substance, a water-soluble (meth)acrylic polymer, water, a surfactant, and poly(methyl acrylate/2-ethylhexyl acrylate), and the surfactant comprises a polyethylene glycol fatty acid ester or a polyoxyethylene sorbitan fatty acid ester.
Abstract translation: 凝胶贴剂依次包括基底织物，粘合剂层和剥离衬垫，其中粘合剂层含有生理活性物质，水溶性（甲基）丙烯酸聚合物，水，表面活性剂和聚（丙烯酸甲酯 丙烯酸-2-乙基己酯），表面活性剂包括聚乙二醇脂肪酸酯或聚氧乙烯脱水山梨糖醇脂肪酸酯。
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Patent Agency Ranking
公开(公告)号：US20160206569A1
公开(公告)日：2016-07-21
申请号：US14913455
申请日：2014-08-21
Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
Inventor： Keiichiro TSURUSHIMA , Yasuhisa KOSE , Seiichiro TSURU , Shinji YAMASOTO , Takaaki YOSHINAGA
IPC: A61K9/70
CPC classification number: A61K9/7061 , A61L15/225 , A61L15/585 , A61L15/60 , C08F220/14 , C08L33/02 , C08L71/00 , C08L33/08 , C08F2220/1858
Abstract: A gel patch comprising a plaster layer on a support, the plaster layer comprising a mixture of at least a neutralized polyacrylic acid, a poly(methyl acrylate/2-ethylhexyl acrylate) emulsion, and water, wherein the poly(methyl acrylate/2-ethylhexyl acrylate) emulsion is an emulsion having an evaporation residue of 57 to 61% by heating at or above the boiling point of the medium and is present in an amount of at least 2.5 times and preferably at least 3 times the mass of the neutralized polyacrylic acid.
Abstract translation: 一种凝胶贴片，其包含支撑体上的膏药层，所述膏药层包含至少中和的聚丙烯酸，聚（丙烯酸甲酯/丙烯酸2-乙基己酯）乳液和水的混合物，其中所述聚（丙烯酸甲酯/ 丙烯酸乙基己酯）乳液是通过在介质沸点以上加热而蒸发残留物为57〜61％的乳液，其存在量为中和的聚丙烯酸的质量的至少2.5倍，优选至少3倍 酸。
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公开(公告)号：US20210077393A1
公开(公告)日：2021-03-18
申请号：US16975171
申请日：2019-02-19
Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
Inventor： Toshihiro NAKANISHI , Yuko NAGASE , Shinya MATSUMURA , Yasuhisa KOSE
Abstract: The present invention provides an emulsified gel composition comprising diclofenac sodium, water, a gelling agent, an antioxidant, and a surfactant having an HLB of 14 or more, in which the gelling agent is a nonionic water-soluble polymer.
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公开(公告)号：US20170348248A1
公开(公告)日：2017-12-07
申请号：US15537952
申请日：2015-12-14
Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
Inventor： Keiichiro TSURUSHIMA , Yasuhisa KOSE , Takaaki YOSHINAGA
IPC: A61K9/70 , A61K31/618 , A61K47/14 , A61K47/26
CPC classification number: A61K9/7061 , A61K31/618 , A61K47/14 , A61K47/26
Abstract: The present invention provides a gel patch comprising a base fabric, an adhesive layer, and a release liner in this order, wherein the adhesive layer contains a physiologically active substance, a water-soluble (meth)acrylic polymer, water, a surfactant, and poly(methyl acrylate/2-ethylhexyl acrylate), and the surfactant comprises a polyethylene glycol fatty acid ester or a polyoxyethylene sorbitan fatty acid ester.
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公开(公告)号：US20220079879A1
公开(公告)日：2022-03-17
申请号：US17536295
申请日：2021-11-29
Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
Inventor： Shinya MATSUMURA , Toshihiro NAKANISHI , Yasuhisa KOSE
Abstract: The present invention provides an emulsified gel composition comprising a physiologically active substance, water, a gelling agent, an anti-peeling agent, and a surfactant having an HLB value of 18 to 20, in which the gelling agent is a nonionic water-soluble polymer, and the anti-peeling agent is one or more compounds selected from the group consisting of sucrose, sorbitol, polyethylene glycol, glycerin, a (meth)acrylic-based polymer compound, and a polyoxyethylene hydrogenated castor oil.
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公开(公告)号：US20180015049A1
公开(公告)日：2018-01-18
申请号：US15547645
申请日：2016-02-05
Applicant: HISAMITSU PHARMACEUTICAL CO., INC.
Inventor： Kentaro NAKASHIMA , Masahiro SATO , Yasuhisa KOSE , Takaaki YOSHINAGA
IPC: A61K9/70 , A61K31/045 , A61F13/00 , A61F13/02 , A61K47/34 , A61K31/618
CPC classification number: A61K9/7053 , A61F13/00063 , A61F13/0243 , A61F13/0253 , A61K9/7076 , A61K31/045 , A61K31/618 , A61K47/06 , A61K47/34 , A61L15/00 , B32B5/02 , B32B27/00
Abstract: Disclosed is an adhesive patch having a support and an adhesive agent layer laminated on the support, wherein the support consists of spunlace nonwoven fabric, the adhesive agent layer comprises an SIS block copolymer and liquid paraffin, the adhesive patch has a first direction, which is a predetermined reference axis direction, and a second direction, which is orthogonal to the first direction, and a bending resistance in the first direction of the adhesive patch is 18 to 30 mm.
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