公开(公告)号：US3578565A

公开(公告)日：1971-05-11

申请号：US3578565D

申请日：1968-10-01

Applicant: HOFFMANN LA ROCHE

Inventor： SCHOCHER ARNO JOHANNES ,  FURST ANDOR ,  ELS HANS ,  BECHER ELISABETH ,  GROSS GISELA

IPC: C12P33/16 ,  C07J1/00 ,  C12P33/00 ,  C07C167/18

CPC classification number: C12P33/00 ,  Y10S435/911

Abstract: MICROBIOLOGICAL PROCESS FOR PREPARING 17-OXYGENATED ANDROSTANES BY SUBJECTING 20-OXYGENATED PREGNANES TO THE ACTION OF A CULTURE OF THE FUNGUS GLIOCLADIUM ROSEUM. THE STEROIDS PREPARED ARE KNOW COMPOUNDS WHICH ARE PHARMACEUTICALLY USEFUL AS ANDROGENIC AGENTS AND AS INTERMEDIATES WHICH CAN BE CONVERTED TO KNOWN COMPOUNDS WHICH ARE PROGESTATIONAL AGENTS.