公开(公告)号：US20150299220A1

公开(公告)日：2015-10-22

申请号：US14648399

申请日：2013-12-04

Applicant: HOFFMANN-LA ROCHE INC.

Inventor： Baledi DHURWASULU ,  Uwe GRETHER ,  Matthias NETTEKOVEN ,  Stephan ROEVER ,  Mark ROGERS-EVANS ,  Tanja SCHULZ-GASCH

IPC: C07D498/08 ,  C07D403/14 ,  C07D417/14 ,  C07D413/14 ,  C07D491/107 ,  C07D403/06 ,  C07D403/04

CPC classification number: C07D498/08 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/14 ,  C07D413/06 ,  C07D413/14 ,  C07D417/14 ,  C07D491/107

Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) is a CB2 receptor agonist for use in the treatment of several disorders, such as pain, atherosclerosis and glaucoma.

Abstract translation: 本发明涉及式（I）化合物，其中R 1至R 4如说明书和权利要求中所定义。 式（I）化合物是用于治疗几种疾病如疼痛，动脉粥样硬化和青光眼的CB2受体激动剂。