公开(公告)号：US20210047251A1

公开(公告)日：2021-02-18

申请号：US17085331

申请日：2020-10-30

Applicant: HONEYWELL INTERNATIONAL INC.

Inventor： Sudip Mukhopadhyay ,  Cheryl L. Bortz ,  Barbara A. Light ,  Cheryl L. Cantlon ,  Robert C. Johnson

IPC: C07C17/21 ,  C07C17/23 ,  C07C17/25 ,  C07C21/18

Abstract: Disclosed is a process for the synthesis of fluorinated olefins, and in particularly preferred embodiments tetrafluorinated olefins having F on an unsaturated, non-terminal carbon, such as 2,3,3,3-tetrafluoropropene. The preferred processes of the present invention in accordance with one embodiment generally comprise: (a) reacting a compound of formula (I) X1X2  (I) with a compound of formula (II) CX1X2X3CX1═CX1X2  (II) to produce a reaction product comprising a compound of formula (III) CF3CHX1CH2X2  (III), and (b) exposing said compound of formula (III) to reaction conditions effective to convert said compound of formula (III) to a compound of formula (IV) CF3CZ═CH2  (IV) wherein X1, X2, and X3 are each independently selected from the group consisting of hydrogen, chlorine, bromine, fluorine and iodine, provided that X1 and X2 in formula (I) are not both hydrogen and Z is Cl, I, Br, or F.

公开(公告)号：US20190263736A1

公开(公告)日：2019-08-29

申请号：US16112058

申请日：2018-08-24

Applicant: HONEYWELL INTERNATIONAL INC.

Inventor： Sudip Mukhopadhyay ,  Hsueh S. Tung ,  Michael Van Der Puy ,  Daniel C. Merkel ,  Jing Ji Ma ,  Cheryl L. Bortz ,  Barbara A. Light ,  Steven D. Phillips ,  Rajesh K. Dubey

IPC: C07C17/25 ,  C07C21/18 ,  C07C17/278 ,  C07C17/272 ,  C07C17/269 ,  C07C17/26 ,  C07C17/00 ,  C07C17/20 ,  C07C17/087 ,  C07C17/04 ,  C07C17/21

Abstract: Disclosed are processes for the production of fluorinated olefins, preferably adapted to commercialization of CF3CF═CH2 (1234yf). Three steps may be used in preferred embodiments in which a feedstock such as CCl2═CClCH2Cl (which may be purchased or synthesized from 1,2,3-trichloropropane) is fluorinated (preferably with HF in gas-phase in the presence of a catalyst) to synthesize a compound such as CF3CCl═CH2, preferably in a 80-96% selectivity. The CF3CCl═CH2 is preferably converted to CF3CFClCH3 (244-isomer) using a SbCl5 as the catalyst which is then transformed selectively to 1234yf, preferably in a gas-phase catalytic reaction using activated carbon as the catalyst. For the first step, a mixture of Cr2O3 and FeCl3/C is preferably used as the catalyst to achieve high selectivity to CF3CCl═CH2 (96%). In the second step, SbCl5/C is preferably used as the selective catalyst for transforming 1233xf to 244-isomer, CF3CFClCH3. The intermediates are preferably isolated and purified by distillation and used in the next step without further purification, preferably to a purity level of greater than about 95%.

公开(公告)号：US20160145176A1

公开(公告)日：2016-05-26

申请号：US14797699

申请日：2015-07-13

Applicant: HONEYWELL INTERNATIONAL INC.

Inventor： Sudip Mukhopadhyay ,  Cheryl L. Bortz ,  Barbara A. Light ,  Cheryl L. Cantlon ,  Robert C. Johnson

IPC: C07C17/21

CPC classification number: C07C17/21 ,  C07C17/23 ,  C07C17/25 ,  C07C21/18 ,  C07C19/08

Abstract: Disclosed is a process for the synthesis of fluorinated olefins, and in particularly preferred embodiments tetrafluorinated olefins having F on an unsaturated, non-terminal carbon, such as 2,3,3,3-tetrafluoropropene. The preferred processes of the present invention in accordance with one embodiment generally comprise:(a) reacting a compound of formula (I) X1X2   (I) with a compound of formula (II) CX1X2X3CX1═CX1X2   (II) to produce a reaction product comprising a compound of formula (III) CF3CHX1CH2X2   (III), and (b) exposing said compound of formula (III) to reaction conditions effective to convert said compound of formula (III) to a compound of formula (IV) CF3CZ═CH2   (IV) wherein X1, X2, and X3 are each independently selected from the group consisting of hydrogen, chlorine, bromine, fluorine and iodine, provided that X1 and X2 in formula (I) are not both hydrogen and Z is Cl, I, Br, or F.

Abstract translation: 公开了用于合成氟化烯烃的方法，特别优选的实施方案中，在不饱和的非末端碳上具有F的四氟化烯烃如2,3,3,3-四氟丙烯。 根据一个实施方案的本发明的优选方法通常包括：（a）使式（I）X1X2（I）化合物与式（II）化合物CX1X2X3CX1 = CX1X2（II）反应以产生反应产物，其包含 式（III）化合物，CF 3 CHX 1 CH 2 X 2（III）的化合物，和（b）将式（III）化合物暴露于有效将式（III）化合物转化成式（IV）化合物的反应条件：CF 3 CZ = CH 2 ）其中X1，X2和X3各自独立地选自氢，氯，溴，氟和碘，条件是式（I）中的X1和X2不同时为氢，Z为Cl，I，Br， 或F.

公开(公告)号：US20180265434A1

公开(公告)日：2018-09-20

申请号：US15987463

申请日：2018-05-23

Applicant: HONEYWELL INTERNATIONAL INC.

Inventor： Sudip Mukhopadhyay ,  Cheryl L. Bortz ,  Barbara A. Light ,  Cheryl L. Cantlon ,  Robert C. Johnson

IPC: C07C17/21 ,  C07C17/23 ,  C07C17/25 ,  C07C21/18 ,  C07C19/08

CPC classification number: C07C17/21 ,  C07C17/23 ,  C07C17/25 ,  C07C21/18 ,  C07C19/08

Abstract: Disclosed is a process for the synthesis of fluorinated olefins, and in particularly preferred embodiments tetrafluorinated olefins having F on an unsaturated, non-terminal carbon, such as 2,3,3,3-tetrafluoropropene. The preferred processes of the present invention in accordance with one embodiment generally comprise: (a) reacting a compound of formula (I) X1X2  (I) with a compound of formula (II) CX1X2X3CX1═CX1X2  (II) to produce a reaction product comprising a compound of formula (III) CF3CHX1CH2X2  (III), and (b) exposing said compound of formula (III) to reaction conditions effective to convert said compound of formula (III) to a compound of formula (IV) CF3CZ═CH2  (IV) wherein X1, X2, and X3 are each independently selected from the group consisting of hydrogen, chlorine, bromine, fluorine and iodine, provided that X1 and X2 in formula (I) are not both hydrogen and Z is Cl, I, Br, or F.

公开(公告)号：US20160039729A1

公开(公告)日：2016-02-11

申请号：US14822497

申请日：2015-08-10

Applicant: HONEYWELL INTERNATIONAL INC.

Inventor： Hsueh S. Tung ,  Sudip Mukhopadhyay ,  Michael Van Der Puy ,  Daniel C. Merkel ,  Jing Ji Ma ,  Cheryl L. Bortz ,  Barbara A. Light ,  Steven D. Phillips ,  Kim M. Fleming ,  Susan A. Ferguson

IPC: C07C17/23 ,  C07C17/20

CPC classification number: C07C17/23 ,  C07C17/087 ,  C07C17/10 ,  C07C17/206 ,  C07C17/21 ,  C07C17/25 ,  C07C19/08 ,  C07C19/10 ,  C07C21/18

Abstract: Disclosed is a process for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of Formula (I): C(X)3CF2C(X)3  (I) to at least one compound of Formula (II) CF3CF═CHZ  (II) where each X and Z is independently H, F, Cl, I or Br, said process preferably not including any substantial amount of oxygen-containing catalyst in certain embodiments.Preferably Z is H.

Abstract translation: 公开了一种制备氟化有机化合物的方法，包括氢氟丙烯，其优选包括将至少一种式（I）化合物：C（X）3CF 2 C（X）3（I）转化为至少一种式（II）化合物CF 3 CF ≡CHZ（II）其中每个X和Z独立地为H，F，Cl，I或Br，在某些实施方案中，所述方法优选不包括任何显着量的含氧催化剂。 Z优选为