公开(公告)号：US20160363538A1

公开(公告)日：2016-12-15

申请号：US15121632

申请日：2015-02-24

Applicant: HORIBA JOBIN YVON SAS

Inventor： Bertrand DUTERTRE ,  Denis CATTELAN ,  Emmanuel FRETEL

IPC: G01N21/65 ,  G01J3/02 ,  G02B27/00 ,  G02B21/00 ,  G02B21/16 ,  G01J3/44 ,  G02B21/02

CPC classification number: G01N21/65 ,  G01J3/0205 ,  G01J3/44 ,  G01N2021/656 ,  G01N2201/06113 ,  G01N2201/063 ,  G01N2201/068 ,  G02B21/0048 ,  G02B21/0064 ,  G02B21/0076 ,  G02B21/02 ,  G02B21/16 ,  G02B27/0025

Abstract: An optical apparatus for Raman scattering microscopy, includes a laser source (10) suitable for emitting a laser beam (11) at an excitation wavelength λ, a microscope objective (14) suitable for receiving the laser beam (11) and focusing the laser beam in an image plane of the microscope objective (14), the focused laser beam (21) being intended to illuminate a sample (20), an optical system suitable for collecting a Raman scattering optical beam (22), and detection elements (16, 17) suitable for detecting the Raman scattering beam (22) collected. More particularly, the Raman scattering microscopy apparatus further includes an adaptive optics system (31, 32, 33) positioned on an optical path of the excitation laser beam (11), on an optical path of the Raman scattering beam (22) or on an optical path common to the excitation laser beam (11) and the Raman scattering beam (22).

Abstract translation: 一种用于拉曼散射显微镜的光学装置，包括适于发射激发波长λ的激光束（11）的激光源（10），适于接收激光束（11）并将激光束聚焦的显微镜物镜（14） 在显微镜物镜（14）的像平面中，聚焦激光束（21）旨在照射样品（20），适于收集拉曼散射光束（22）的光学系统和检测元件（16， 17）适用于检测所收集的拉曼散射光束（22）。 更具体地，拉曼散射显微镜装置还包括位于激光激光束（11）的光路上的自适应光学系统（31,32,33），在拉曼散射光束（22）的光路上，或者在 激光激光束（11）和拉曼散射光束（22）共用的光路。

公开(公告)号：US20170067805A1

公开(公告)日：2017-03-09

申请号：US15120358

申请日：2015-02-19

Applicant: HORIBA JOBIN YVON SAS

Inventor： Emmanuel MAILLART ,  Cecile LERONDEAU ,  Geraldine MELIZZI ,  Didier-Luc BRUNET ,  Denis CATTELAN

IPC: G01N1/38 ,  G01N21/65

CPC classification number: G01N1/38 ,  G01N21/658 ,  G01N35/08 ,  G01N35/1095 ,  G01N35/1097

Abstract: A system for transferring a fluid sample in a fluid cell, includes a first and a second fluid circuit connected, respectively, to a first and a second inlet-outlet (1, 2) of a fluid cell (10), first injection elements (80) configured so as to inject, in series, into the first fluid circuit (11, 12, 13): a buffer solution, a first separation fluid volume followed by a fluid sample, then a second separation fluid volume and another buffer solution. The system includes first discharge elements arranged on the first fluid circuit near the first inlet-outlet (1), second injection elements (90, 91) arranged on the second fluid circuit (21, 22, 23) near the second inlet-outlet (2), and two-way circulation elements configured so as to circulate the fluid sample in two opposite directions in the fluid cell (10) without the passage of separation fluid into the fluid cell (10).

Abstract translation: 用于将流体样品转移到流体池中的系统包括分别连接到流体池（10）的第一和第二入口 - 出口（1,2）的第一和第二流体回路，第一注入元件（ 80），其被配置为串联地注入到第一流体回路（11,12,13）中：缓冲溶液，第一分离流体体积，随后是流体样品，然后是第二分离流体体积和另一缓冲溶液。 该系统包括布置在第一入口 - 出口（1）附近的第一流体回路上的第一排放元件，在第二入口 - 出口附近设置在第二流体回路（21,22,23）上的第二喷射元件（90,91） 2）和双向循环元件，其构造成使流体单元（10）中的两个相反方向上的流体样品循环，而不使分离流体进入流体池（10）。