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    SAMPLE INJECTOR FOR LIQUID CHROMATOGRAPHY, PARTICULARLY FOR HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
    3.
    发明公开
    SAMPLE INJECTOR FOR LIQUID CHROMATOGRAPHY, PARTICULARLY FOR HIGH PERFORMANCE LIQUID CHROMATOGRAPHY 审中-公开

    公开(公告)号：US20240167985A1

    公开(公告)日：2024-05-23

    申请号：US18493974

    申请日：2023-10-25

    申请人： DIONEX SOFTRON GMBH

    发明人： Hermann HOCHGRAEBER

    IPC分类号： G01N30/20 ,  G01N30/32 ,  G01N35/10

    CPC分类号： G01N30/20 ,  G01N30/32 ,  G01N35/1097 ,  G01N2030/201 ,  G01N30/24

    摘要： A sample injection method for liquid chromatography is performed with an injection valve having a waste port, two sample loop ports, and two high-pressure ports. One high-pressure port can be connected to a pump and the other high-pressure port can be connected to a chromatography column. A sample loop is connected to one of the sample loop ports on one end and to a pump volume of a sample conveying device on the other end. A section of the sample loop can be separated to facilitate receiving a sample fluid in the sample loop. A control unit controls the injection valve and the sample conveying device. The sample injector allows a sample to be loaded into the sample loop and then pressurized to an operating pressure prior to injecting the sample into the chromatography column. The sample loop may also be isolated from the operating pressure for facilitating depressurization of the loop.

    AUTOMATED INLINE NANOPARTICLE STANDARD MATERIAL ADDITION
    6.
    发明公开
    AUTOMATED INLINE NANOPARTICLE STANDARD MATERIAL ADDITION 审中-公开

    公开(公告)号：US20230408542A1

    公开(公告)日：2023-12-21

    申请号：US18205131

    申请日：2023-06-02

    申请人： Elemental Scientific, Inc.

    发明人： Austin Schultz

    IPC分类号： G01N35/10 ,  H01J49/10

    CPC分类号： G01N35/1097 ,  G01N2035/00524 ,  H01J49/105

    摘要： Systems and methods for automated handling and maintaining nanoparticle standard solutions in a substantially homogenous state with controlled introduction to a fluid sample are described. A system embodiment includes, but is not limited to, an agitator configured to mix a nanoparticle standard solution in a container to provide a mixed nanoparticle standard having a substantially homogenous distribution of nanoparticles; and a fluid preparation system fluidically coupled with the container to receive the mixed nanoparticle standard and direct the mixed nanoparticle standard to a fluid sample stream for inline mixing therewith.

    FLUIDIC NETWORK FOR POSITIVE DISPLACEMENT ASEPTIC SAMPLING
    7.
    发明公开
    FLUIDIC NETWORK FOR POSITIVE DISPLACEMENT ASEPTIC SAMPLING 审中-公开

    公开(公告)号：US20230358777A1

    公开(公告)日：2023-11-09

    申请号：US18311471

    申请日：2023-05-03

    申请人： Waters Technologies Corporation

    发明人： Sylvain Gilles Cormier ,  Michael O. Fogwill

    IPC分类号： G01N35/10 ,  G01N1/20 ,  G01N1/14

    CPC分类号： G01N35/1097 ,  G01N1/14 ,  G01N1/20

    摘要： Described are a fluidic network and method for aseptic sampling from a process source. The fluidic network includes a valve that isolates the valve port that receives the process sample from all other valve ports except when the process sample flows through the valve. The fluidic network further includes a sample treatment module having a filter element and a sample preparation element to prepare the process sample for analysis. A positive displacement pump operates to draw the process sample into the fluidic network and to push a portion of the acquired process sample through the sample treatment module before dispensing the treated process sample from the fluidic network. Process sample remaining in a process sample supply line leading from the process source to the process inlet port may be pushed back to the process source via a gas flow to limit the acquired process sample volume.

    Mass-Spectrometer Systems And Methods
    10.
    发明申请
    Mass-Spectrometer Systems And Methods 审中-公开

    公开(公告)号：US20190234957A1

    公开(公告)日：2019-08-01

    申请号：US16100876

    申请日：2018-08-10

    申请人： PureHoney Technologies, Inc.

    发明人： Can Ozbal

    IPC分类号： G01N33/68 ,  G01N33/94 ,  G01N1/34 ,  G01N35/10

    CPC分类号： G01N33/6848 ,  G01N1/34 ,  G01N33/9446 ,  G01N35/1097 ,  G01N2001/4088

    摘要： Embodiments of the present disclosure present novel systems, devices and methods for an automated biological sample analysis using mass-spectrometry. The time from sample introduction to the reporting of data, in some embodiments, takes a relatively short amount of time (e.g., several minutes). In some embodiments, a biological sample to be analyzed is a blood sample. For many applications, only a single drop of blood may be sufficient. Through the use of a mixture of standards with unique molecular mass, a quantitative analysis of the target analyte can be performed in a single MS run (for example), eliminating the need to create and analyze standard curves. One advantage of such embodiments may be that the system, devices, and methods can eliminate the need for batch creation since the requirement to amortize the time and effort of creating and analyzing standard curves can be eliminated.