公开(公告)号：US20250092075A1

公开(公告)日：2025-03-20

申请号：US18964637

申请日：2024-12-01

Applicant: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Qian WAN ,  Lingkui MENG ,  Jing ZENG ,  Yulin TAN ,  Yue YIN ,  Qin ZHANG

IPC: C07H1/00 ,  C07H15/04 ,  C07H15/12 ,  C07H15/14 ,  C07H15/18 ,  C07H15/207 ,  C07H17/07 ,  C07H19/04 ,  C07H19/052 ,  C07H19/06 ,  C07H19/16 ,  C07H19/23

Abstract: A glycosylation method involving a trivalent iodine reagent, wherein a glycosyl donor (I) is activated in the presence of a trivalent iodine reagent and a transition metal catalyst, and then reacts with a acceptor (II) under acid catalysis or directly to obtain a glycosylation product (III); in the glycosyl donor (I), Gly is a glycosyl group in which one or more hydroxyl groups on the sugar ring are protected by a protecting group; X is an oxygen, sulfur, or selenium atom; R is an alkyl group or an aryl group; the acceptor (II) is a nucleophile selected from sugars, alcohols, phenols, flavonoids, carboxylic acids, phosphates, pyrimidines, purines, amides, sulfonamides, guanidines, arylamines, indoles, enol silyl ethers, thiols, or thiophenol containing one or more free hydroxyl groups.

公开(公告)号：US20190017362A1

公开(公告)日：2019-01-17

申请号：US15749583

申请日：2016-09-29

Applicant: HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY

Inventor： Yi LIU ,  Fuchang LIN ,  Yuan PAN ,  Qin ZHANG ,  Hua LI ,  Zhiyuan LI ,  Siwei LIU

IPC: E21B43/26 ,  E21B28/00 ,  E21B43/00

CPC classification number: E21B43/26 ,  B08B7/026 ,  B08B9/0326 ,  E21B28/00 ,  E21B37/00 ,  E21B43/003

Abstract: The invention discloses a pipeline descaling and rock stratum fracturing device based on electro-hydraulic pulse shock waves, comprising a ground low-voltage control device, a transmission cable and an electro-hydraulic pulse shock wave transmitter. The invention generates available high-strength shock waves with repetition frequency to bombard a specific position of the pipeline or rock stratum so as to achieve the effect of pipeline descaling and rock stratum fracturing; the breakdown field strength of the liquid gap can be effectively reduced to improve the conversion efficiency of the electrical energy to the mechanical energy of the electro-hydraulic pulse shock wave so as to obtain a high-strength electro-hydraulic pulse shock wave; the transmitting cavity adopts a parabolic focusing cavity, and through refraction and reflection of the rotating parabolic cavity, the shock wave is focused in a preset direction and radiates outwards to act on the pipeline dirt or rock stratum while ensuring that the shock wave has no longitudinal component and does not will not damage the liquid within the pipeline and the pipeline sheath, so that the effect of pipeline descaling or rock stratum fracturing is improved after focusing. The invention has the advantages of effectively removing the pipeline dirt, fracturing the rock stratum and improving the permeability as well as high reliability, environmental friendliness and low cost.