公开(公告)号：US09049856B2

公开(公告)日：2015-06-09

申请号：US13699792

申请日：2011-05-24

申请人： Haisul C.Y. Chang ,  Victor Fernández Gallego ,  María Iñiguez Martínez ,  Jose Miguel López Novoa ,  Jesús María Prieto Valtueña ,  Juan Ruiz Echeverría

发明人： Haisul C.Y. Chang ,  Victor Fernández Gallego ,  María Iñiguez Martínez ,  Jose Miguel López Novoa ,  Jesús María Prieto Valtueña ,  Juan Ruiz Echeverría

IPC分类号： A01N1/00 ,  A01N1/02

CPC分类号： A01N1/0221 ,  A01N1/0226

摘要： The present invention relates to a cold organ preservation composition for transplantation comprising a cold organ preservation solution and cardiotrophin-1 or a functionally equivalent variant thereof. The invention also relates to methods and kits for the preparation of said composition, the uses thereof for the cold organ protection and/or preservation for transplantation (particularly for kidney, lung and heart) and also to the cold preservation methods and cold-preserved isolated organs by these methods.

摘要翻译： 本发明涉及一种用于移植的冷器官保存组合物，其包含冷器官保存液和心肌营养素-1或其功能等价变体。 本发明还涉及用于制备所述组合物的方法和试剂盒，其用于冷器官保护和/或移植保存（特别是肾，肺和心脏）的用途，以及冷保存方法和冷保存的分离物 器官通过这些方法。

公开(公告)号：US20130130225A1

公开(公告)日：2013-05-23

申请号：US13699792

申请日：2011-05-24

申请人： Haisul C.Y. Chang ,  Victor Fernández Gallego ,  María Iñiguez Martínez ,  Jose Miguel Lopez Novoa ,  Jesús María Prieto Valtueña ,  Juan Ruiz Echeverría

发明人： Haisul C.Y. Chang ,  Victor Fernández Gallego ,  María Iñiguez Martínez ,  Jose Miguel Lopez Novoa ,  Jesús María Prieto Valtueña ,  Juan Ruiz Echeverría

IPC分类号： A01N1/02

CPC分类号： A01N1/0221 ,  A01N1/0226

摘要： The present invention relates to a cold organ preservation composition for transplantation comprising a cold organ preservation solution and cardiotrophin-1 or a functionally equivalent variant thereof. The invention also relates to methods and kits for the preparation of said composition, the uses thereof for the cold organ protection and/or preservation for transplantation (particularly for kidney, lung and heart) and also to the cold preservation methods and cold-preserved isolated organs by these methods.

摘要翻译： 本发明涉及一种用于移植的冷器官保存组合物，其包含冷器官保存液和心肌营养素-1或其功能等价变体。 本发明还涉及用于制备所述组合物的方法和试剂盒，其用于冷器官保护和/或移植保存（特别是肾，肺和心脏）的用途，以及冷保存方法和冷保存的分离物 器官通过这些方法。