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公开(公告)号:US5512569A
公开(公告)日:1996-04-30
申请号:US408069
申请日:1995-03-21
申请人: Hamid A. Mansour , Thierry Taverne , Raymond Houssin , Isabelle Lesieur , Patrick Depreux , Geard Adam , Daniel-Henri Caignard , Pierre Renard , Marie-Claire Rettori
发明人: Hamid A. Mansour , Thierry Taverne , Raymond Houssin , Isabelle Lesieur , Patrick Depreux , Geard Adam , Daniel-Henri Caignard , Pierre Renard , Marie-Claire Rettori
IPC分类号: A61K31/425 , A61K31/428 , A61K31/445 , A61K31/495 , A61K31/535 , A61K31/54 , A61P25/00 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P43/00 , C07D277/68 , C07D417/02
CPC分类号: C07D277/68
摘要: The invention relates to the compounds of formula (I): ##STR1## in which R.sub.1 and R.sup.2 are as defined in the description, the optical isomers thereof,and an addition salt thereof with a pharmaceutically-acceptable acid or base, and medicinal product useful for treating a mammal afflicted with a disease associated with sigma receptors.
摘要翻译: 本发明涉及式(I)化合物:其中R 1和R 2如说明书中所定义,其光学异构体及其与药学上可接受的酸或碱的加成盐,和 用于治疗患有与σ受体相关的疾病的哺乳动物的药用产品。