公开(公告)号：US20060287230A1

公开(公告)日：2006-12-21

申请号：US11390195

申请日：2006-03-28

申请人： Hana Koutnikova ,  Alexis Brice ,  Alain Fournier ,  Laurent Pradier ,  Catherine Prades ,  Isabelle Arnould-Reguigne ,  Marie-Francoise Rosier-Montus ,  Olga Corti

发明人： Hana Koutnikova ,  Alexis Brice ,  Alain Fournier ,  Laurent Pradier ,  Catherine Prades ,  Isabelle Arnould-Reguigne ,  Marie-Francoise Rosier-Montus ,  Olga Corti

IPC分类号： A61K38/17 ,  A61K39/395 ,  C07K14/705 ,  C07K16/28 ,  C07H21/04 ,  C12P21/06

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00 ,  C07K2319/00

摘要： The present invention relates to novel compounds and their uses, in particular their pharmaceutical or diagnostic uses or their use as pharmacological targets. More particularly, the present invention relates to a novel protein, referred to as PAP1, as well as to novel peptides and compounds which are capable of modulating, at least partially, the activity of parkin.

公开(公告)号：US07132396B2

公开(公告)日：2006-11-07

申请号：US09785548

申请日：2001-02-20

申请人： Hana Koutnikova ,  Alexis Brice ,  Alain Fournier ,  Laurent Pradier ,  Catherine Prades ,  Isabelle Arnould-Reguigne ,  Marie-Françoise Rosier-Montus ,  Olga Corti

发明人： Hana Koutnikova ,  Alexis Brice ,  Alain Fournier ,  Laurent Pradier ,  Catherine Prades ,  Isabelle Arnould-Reguigne ,  Marie-Françoise Rosier-Montus ,  Olga Corti

IPC分类号： A61K38/17 ,  C07K14/435

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00 ,  C07K2319/00

摘要： The present invention relates to novel compounds and their uses, in particular their pharmaceutical or diagnostic uses or their use as pharmacological targets. More particularly, the present invention relates to a novel protein, referred to as PAP1, as well as to novel peptides and compounds which are capable of modulating, at least partially, the activity of parkin.

公开(公告)号：US08273548B2

公开(公告)日：2012-09-25

申请号：US11390195

申请日：2006-03-28

申请人： Han Koutnikova ,  Alexis Brice ,  Alain Fournier ,  Laurent Pradier ,  Catherine Prades ,  Isabelle Arnould-Reguigne ,  Marie-Françoise Rosier-Montus ,  Olga Corti

发明人： Han Koutnikova ,  Alexis Brice ,  Alain Fournier ,  Laurent Pradier ,  Catherine Prades ,  Isabelle Arnould-Reguigne ,  Marie-Françoise Rosier-Montus ,  Olga Corti

IPC分类号： C12N15/12 ,  C12N15/63 ,  C12N15/85 ,  C12N1/21

CPC分类号： C07K14/47 ,  A01K2217/05 ,  A61K38/00 ,  A61K48/00 ,  C07K2319/00

摘要： The present invention relates to novel compounds and their uses, in particular their pharmaceutical or diagnostic uses or their use as pharmacological targets. More particularly, the present invention relates to a novel protein, referred to as PAP1, as well as to novel peptides and compounds which are capable of modulating, at least partially, the activity of parkin.

摘要翻译： 本发明涉及新化合物及其用途，特别是其药物或诊断用途或其作为药理学靶标的用途。 更具体地，本发明涉及一种称为PAP1的新型蛋白质，以及能够至少部分调节帕金蛋白酶活性的新型肽和化合物。