-
1.发明授权Target cell-specific non-viral vectors for inserting genes into cells, pharmaceutical compositions comprising such vectors and their use 失效用于将基因插入细胞的靶细胞特异性非病毒载体，包含这种载体的药物组合物及其用途
公开(公告)号：US5916803A
公开(公告)日：1999-06-29
申请号：US799825
申请日：1997-02-13
IPC分类号： C12N15/09 , A61K35/76 , A61K38/00 , A61K38/16 , A61K38/18 , A61K38/28 , A61K39/395 , A61K39/42 , A61K47/48 , A61K48/00 , A61P31/12 , A61P35/00 , C07H21/04 , C12N15/63 , C12N15/79 , C12N15/85 , C12N15/87 , C12N15/88
CPC分类号： C12N15/88 , A61K47/48007 , A61K48/00 , C12N15/87
摘要： Target cell-specific, non-viral vectors for inserting genes into cells, pharmaceuticals composition comprising such vectors, and methods of their use. Target cell-specific, non-viral vectors for inserting at least one gene into cells of an organism, comprising a complex comprising the following components:a) a non-viral carrier for the gene to be inserted,b) a ligand which can bind specifically to the desired target cell,c) a fusion protein for the penetration of the vector into the cytoplasm of the target cell, andd) the gene to be introducedare disclosed. Vectors of this nature are used, for example, in gene therapy.
摘要翻译： 用于将基因插入细胞的靶细胞特异性非病毒载体，包含这种载体的药物组合物及其使用方法。 用于将至少一个基因插入生物体细胞的靶细胞特异性非病毒载体，其包含包含以下组分的复合物：a）待插入基因的非病毒载体，b）可结合的配体 具体涉及所需的靶细胞，c）用于将载体渗透到靶细胞的细胞质中的融合蛋白质，以及d）公开了待引入的基因。 这种性质的载体用于例如基因治疗。
-
2.发明授权Target cell-specific non-viral vectors for inserting genes into cells, pharmaceutical compositions comprising such vectors and their use 失效用于将基因插入细胞的靶细胞特异性非病毒载体，包含这种载体的药物组合物及其用途公开(公告)号：US06358524B1
公开(公告)日：2002-03-19
申请号：US09280068
申请日：1999-03-29
IPC分类号： A61K9127
摘要： Target cell-specific, non-viral vectors for inserting genes into cells, pharmaceuticals composition comprising such vectors, and methods of their use. Target cell-specific, non-viral vectors for inserting at least one gene into cells of an organism, comprising a complex comprising the following components: a) a non-viral carrier for the gene to be inserted, b) a ligand which can bind specifically to the desired target cell, c) a fusion protein for the penetration of the vector into the cytoplasm of the target cell, and d) the gene to be introduced are disclosed. Vectors of this nature are used, for example, in gene therapy.
摘要翻译： 用于将基因插入细胞的靶细胞特异性非病毒载体，包含这种载体的药物组合物及其使用方法。 用于将至少一个基因插入生物体细胞的靶细胞特异性非病毒载体，其包含包含以下组分的复合物：a）待插入基因的非病毒载体，b）可结合的配体 具体涉及所需的靶细胞，c）用于将载体渗透入靶细胞的细胞质的融合蛋白，以及d）将要引入的基因。 这种性质的载体用于例如基因治疗。
-
搜索结果
2 条记录 (耗时 0.021 秒)
