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1.发明授权Cationically substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use 有权阳离子取代的二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07671047B2
公开(公告)日：2010-03-02
申请号：US10463789
申请日：2003-06-18
申请人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
发明人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC分类号： C07D205/08 , C07D403/12 , A61K31/397 , A61K31/4995 , A61K31/5377 , A61K31/496 , A61K31/4025 , A61K31/541 , A61P3/10
CPC分类号： C07D487/08 , C07D205/08
摘要： One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of the compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
摘要翻译： 本发明的一个实施方案涉及式I化合物，其中R 1，R 2，R 3，R 4，R 5和R 6具有说明书中给出的含义。 本发明的其它实施方案涉及式I化合物的生理上可接受的盐，其制备方法和包含这些化合物的药物。 本发明的化合物适合用作例如降血脂药。
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2.发明授权Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use 有权环取代的二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07407938B2
公开(公告)日：2008-08-05
申请号：US11544746
申请日：2006-10-10
申请人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
发明人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC分类号： C07D205/08 , C07K2/00 , A61K38/08 , A61K31/05 , A61K31/06 , A61K31/07 , A61K31/397 , A61P9/10 , A61P3/06
CPC分类号： C07D403/12 , C07D205/08 , C07D453/02 , C07D487/08 , Y10S930/28
摘要： One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
摘要翻译： 本发明的一个实施方案涉及式I化合物，其中R 1，R 2，R 3，R 4，R 5和R 6具有说明书中给出的含义。 本发明的其它实施方案涉及式I化合物的生理上可接受的盐，其制备方法和包含这些化合物的药物。 本发明的化合物适合用作例如降血脂药。
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3.发明授权Diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use 失效具有改善的生理特性的二苯基氮杂环丁酮，其制备方法，包含该化合物的药物及其用途公开(公告)号：US07205290B2
公开(公告)日：2007-04-17
申请号：US10813954
申请日：2004-03-31
申请人： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
发明人： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
IPC分类号： C07D205/08 , A61K31/397 , A61P9/10 , A61P3/06 , C07C229/22
CPC分类号： C07C233/18 , C07D205/08
摘要： The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
摘要翻译： 本发明涉及式1的化合物
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4.发明申请NOVEL DIPHENYLAZETIDINONE WITH IMPROVED PHYSIOLOGICAL PROPERTIES, PROCESS FOR ITS PREPARATION, MEDICAMENTS COMPRISING THIS COMPOUND, AND ITS USE 失效具有改善的生理特性的新型二氢噻吩酮，其制备方法，包含该化合物的药物及其用途公开(公告)号：US20070197498A1
公开(公告)日：2007-08-23
申请号：US11690993
申请日：2007-03-26
申请人： Gerhard JAEHNE , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
发明人： Gerhard JAEHNE , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
IPC分类号： A61K31/397 , C07D205/02
CPC分类号： C07C233/18 , C07D205/08
摘要： Novel diphenylazetidinone, process for its preparation, medicaments comprising this compound and their use The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
摘要翻译： 新型二苯基氮杂环丁酮，其制备方法，包含该化合物的药物及其用途本发明涉及式1的化合物及其生理上可接受的盐。 该化合物例如可用作降血脂药物。
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公开(公告)号：US20070043017A1
公开(公告)日：2007-02-22
申请号：US11544718
申请日：2006-10-10
申请人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
发明人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC分类号： A61K31/397 , C07D205/02 , C07D403/02
CPC分类号： C07D403/12 , C07D205/08 , C07D453/02 , C07D487/08 , Y10S930/28
摘要： One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
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6.发明授权Diphenylazetidinone derivatives, process for their preparation, medicaments comprising these compounds and their use 有权二苯基氮杂环丁酮衍生物，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US06498156B2
公开(公告)日：2002-12-24
申请号：US10021028
申请日：2001-12-19
申请人： Heiner Glombik , Werner Kramer , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schaefer
发明人： Heiner Glombik , Werner Kramer , Stefanie Flohr , Wendelin Frick , Hubert Heuer , Gerhard Jaehne , Andreas Lindenschmidt , Hans-Ludwig Schaefer
IPC分类号： A61K31397
CPC分类号： C07D401/14 , C07D205/08 , C07D409/12
摘要： Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics.
摘要翻译： 其中R1，R2，R3，R4，R5和R6具有说明书中给出的含义的式I化合物及其生理上可接受的盐。 该化合物适合用作例如降血脂药。
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7.发明授权Diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use 失效具有改善的生理特性的二苯基氮杂环丁酮，其制备方法，包含该化合物的药物及其用途公开(公告)号：US07772429B2
公开(公告)日：2010-08-10
申请号：US11690993
申请日：2007-03-26
申请人： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
发明人： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
IPC分类号： C07C229/08 , C07C229/12
CPC分类号： C07C233/18 , C07D205/08
摘要： The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
摘要翻译： 本发明涉及式1的化合物及其生理上可接受的盐。 该化合物例如可用作降血脂药物。
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8.发明授权Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use 有权环取代的二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07176194B2
公开(公告)日：2007-02-13
申请号：US10463807
申请日：2003-06-18
申请人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
发明人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC分类号： C07D205/08 , C07D227/00 , A61K31/397 , A61P3/06 , A61P9/10
CPC分类号： C07D403/12 , C07D205/08 , C07D453/02 , C07D487/08 , Y10S930/28
摘要： One embodiment of the invention relates to compounds of the formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of compounds of formula I, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
摘要翻译： 本发明的一个实施方案涉及式I化合物，其中R 1，R 2，R 3，R 4，R 5和R 6具有说明书中给出的含义。 本发明的其它实施方案涉及式I化合物的生理上可接受的盐，其制备方法和包含这些化合物的药物。 本发明的化合物适合用作例如降血脂药。
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9.发明授权Acid-group-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use 有权酸基取代的二苯基氮杂环丁酮，其制备方法，包含这些化合物的药物及其用途公开(公告)号：US07176193B2
公开(公告)日：2007-02-13
申请号：US10463388
申请日：2003-06-18
申请人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
发明人： Gerhard Jaehne , Wendelin Frick , Stefanie Flohr , Andreas Lindenschmidt , Heiner Glombik , Werner Kramer , Hubert Heuer , Hans-Ludwig Schaefer
IPC分类号： C07D205/08 , C07D227/00 , A61K31/397 , A61P3/06 , A61P9/10
CPC分类号： C07D205/08
摘要： One embodiment of the invention relates to compounds of the formula I: in which R1, R2, R3, R4, R5 and R6 have the meanings given in the specification. Other embodiments of the invention relate to physiologically acceptable salts of the compounds of formula 1, to processes for their preparation and to medicaments comprising these compounds. The compounds of the invention are suitable for use, for example, as hypolipidemics.
摘要翻译： 本发明的一个实施方案涉及式I化合物：其中R1，R2，R3，R4，R5和R6具有说明书中给出的含义。 本发明的其它实施方案涉及式1化合物的生理上可接受的盐，其制备方法和包含这些化合物的药物。 本发明的化合物适合用作例如降血脂药。
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10.发明申请Nover diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use 失效具有改善的生理特性的二苯基氮杂环丁酮，其制备方法，包含该化合物的药物及其用途公开(公告)号：US20050020563A1
公开(公告)日：2005-01-27
申请号：US10813954
申请日：2004-03-31
申请人： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
发明人： Gerhard Jaehne , Wendelin Frick , Andreas Lindenschmidt , Stefanie Flohr , Hubert Heuer , Hans-Ludwig Schaefer , Werner Kramer , Eric Galia , Heiner Glombik
IPC分类号： A61P3/06 , C07C233/18 , C07D205/08 , A61K31/397
CPC分类号： C07C233/18 , C07D205/08
摘要： The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
摘要翻译： 本发明涉及式1的化合物及其生理上可接受的盐。 该化合物例如可用作降血脂药物。
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