专利检索 ap:("Helen Kathleen Danagher" OR "Geoffrey Gerard Hayes" OR "Gerhard Josef Heun" OR "Hassan Mohammad" OR "Malcolm Walden" OR "Jonathon Oliver Whitehouse") AND inv:"Helen Kathleen Danagher" 第 1 页

1.

发明授权
Immediate release pharmaceutical compositions comprising oxycodone and naloxone 有权
标题翻译：包含羟考酮和纳洛酮的立即释放药物组合物

公开(公告)号：US09271940B2

公开(公告)日：2016-03-01

申请号：US13255504

申请日：2010-03-10

申请人： Helen Kathleen Danagher , Geoffrey Gerard Hayes , Gerhard Josef Heun , Hassan Mohammad , Malcolm Walden , Jonathon Oliver Whitehouse

发明人： Helen Kathleen Danagher , Geoffrey Gerard Hayes , Gerhard Josef Heun , Hassan Mohammad , Malcolm Walden , Jonathon Oliver Whitehouse

IPC分类号： A61K31/439 , A61P29/02 , A61K9/20 , A61K31/485

CPC分类号： A61K31/485 , A61K9/0053 , A61K9/2018 , A61K9/2059 , A61K2300/00

摘要： The present invention pertains to oral immediate release pharmaceutical compositions suitable for treating patients suffering from pain comprising oxycodone and naloxone or their pharmaceutically acceptable salts.

摘要翻译： 本发明涉及适用于治疗患有疼痛的患者的口服立即释放药物组合物，其包含羟考酮和纳洛酮或其药学上可接受的盐。

2.

发明授权
Pharmaceutical compositions comprising hydromorphone and naloxone 有权

公开(公告)号：US09700508B2

公开(公告)日：2017-07-11

申请号：US13697197

申请日：2011-05-10

申请人： Helen Kathleen Danagher , Hassan Mohammad , Malcolm Walden , Geoffrey Gerard Hayes , Jonathon Oliver Whitehouse , Thinnayam Naganathan Krishnamurthy , Ricardo Alberto Vargas Rincon

发明人： Helen Kathleen Danagher , Hassan Mohammad , Malcolm Walden , Geoffrey Gerard Hayes , Jonathon Oliver Whitehouse , Thinnayam Naganathan Krishnamurthy , Ricardo Alberto Vargas Rincon

IPC分类号： A61K9/00 , A61K9/20 , A61K9/28 , A61K9/50 , A61K31/485 , A61K9/16

CPC分类号： A61K9/0002 , A61K9/1635 , A61K9/1652 , A61K9/1676 , A61K9/2027 , A61K9/2054 , A61K9/2095 , A61K9/2846 , A61K9/2866 , A61K9/5078 , A61K31/485 , A61K2300/00

摘要： The present invention relates to prolonged release pharmaceutical dosage forms, the manufacture thereof as well as their use for administration to human beings.

3.

发明申请
PHARMACEUTICAL COMPOSITIONS COMPRISING HYDROMORPHONE AND NALOXONE 有权
标题翻译：含有氢键和纳洛酮的药物组合物

公开(公告)号：US20130178492A1

公开(公告)日：2013-07-11

申请号：US13697197

申请日：2011-05-10

申请人： Helen Kathleen Danagher , Hassan Mohammad , Malcolm Walden , Geoffrey Gerard Hayes , Jonathon Oliver Whitehouse , Thinnayam Naganathan Krishnamurthy , Ricardo Alberto Vargas Rincon

发明人： Helen Kathleen Danagher , Hassan Mohammad , Malcolm Walden , Geoffrey Gerard Hayes , Jonathon Oliver Whitehouse , Thinnayam Naganathan Krishnamurthy , Ricardo Alberto Vargas Rincon

IPC分类号： A61K9/00

CPC分类号： A61K9/0002 , A61K9/1635 , A61K9/1652 , A61K9/1676 , A61K9/2027 , A61K9/2054 , A61K9/2095 , A61K9/2846 , A61K9/2866 , A61K9/5078 , A61K31/485 , A61K2300/00

摘要： The present invention relates to prolonged release pharmaceutical dosage forms, the manufacture thereof as well as their use for administration to human beings.

摘要翻译： 本发明涉及延长释放的药物剂型，其制备方法及其用于给予人类的用途。

4.

发明授权
Pharmaceutical spheroids 有权
标题翻译：药物球体

公开(公告)号：US09034373B2

公开(公告)日：2015-05-19

申请号：US12225228

申请日：2007-03-16

申请人： Malcolm Walden , Hassan Mohammad , Geoffrey Gerard Hayes , Helen Kathleen Danagher , Jonathon Oliver Whitehouse

发明人： Malcolm Walden , Hassan Mohammad , Geoffrey Gerard Hayes , Helen Kathleen Danagher , Jonathon Oliver Whitehouse

IPC分类号： A61K9/16 , A61K9/50 , A61K31/485

CPC分类号： A61K9/1617 , A61K9/1635 , A61K9/5047 , A61K31/485

摘要： According to the invention glyceryl monostearate and a polymeric binder are employed as a spheronising aid in the manufacture of pharmaceutical spheroids containing no or substantially no microcrystalline cellulose. The spheroids can contain one or more therapeutically active agent which undergoes no or substantially no degradation when stored under accelerated temperature and humidity conditions. A coating may be applied to the spheroids; when present, the coating is preferably a controlled release coating.

摘要翻译： 根据本发明，单硬脂酸甘油酯和聚合物粘合剂用作制造不含或基本上不含微晶纤维素的药物球体的滚球助剂。球体可以含有一种或多种治疗活性剂，当在加速的温度和湿度条件下储存时，其不经历或基本上不降解。涂层可以施加到球体上; 当存在时，涂层优选为控释层。

5.

发明申请
PHARMACEUTICAL SPHEROIDS 有权
标题翻译：药用植物

公开(公告)号：US20100047337A1

公开(公告)日：2010-02-25

申请号：US12225228

申请日：2007-03-16

申请人： Malcolm Walden , Hassan Mohammad , Geoffrey Gerard Hayes , Helen Kathleen Danagher , Jonathan Oliver Whitehouse

发明人： Malcolm Walden , Hassan Mohammad , Geoffrey Gerard Hayes , Helen Kathleen Danagher , Jonathan Oliver Whitehouse

IPC分类号： A61K9/48 , A61K47/30 , A61K31/439 , A61K9/20 , A61K47/32 , A61P43/00 , B29B9/12 , B29B9/16

CPC分类号： A61K9/1617 , A61K9/1635 , A61K9/5047 , A61K31/485

摘要： According to the invention glyceryl monostearate and a polymeric binder are employed as a spheronising aid in the manufacture of pharmaceutical spheroids containing no or substantially no microcrystalline cellulose. The spheroids can contain one or more therapeutically active agent which undergoes no or substantially no degradation when stored under accelerated temperature and humidity conditions. A coating may be applied to the spheroids; when present, the coating is preferably a controlled release coating.

摘要翻译： 根据本发明，单硬脂酸甘油酯和聚合物粘合剂用作制造不含或基本上不含微晶纤维素的药物球体的滚球助剂。球体可以含有一种或多种治疗活性剂，当在加速的温度和湿度条件下储存时，其不经历或基本上不降解。涂层可以施加到球体上; 当存在时，涂层优选为控释层。

6.

发明授权
Particulates 有权
标题翻译：颗粒物

公开(公告)号：US08920836B2

公开(公告)日：2014-12-30

申请号：US10588978

申请日：2005-02-11

申请人： Geoffrey Gerard Hayes , Hassan Mohammad , Harjit Tamber , Malcolm Walden , Steve Whitelock , Helen Kathleen Danagher , Derek Allan Prater

发明人： Geoffrey Gerard Hayes , Hassan Mohammad , Harjit Tamber , Malcolm Walden , Steve Whitelock , Helen Kathleen Danagher , Derek Allan Prater

IPC分类号： A61K9/22 , A61K9/16

CPC分类号： A61K9/1694 , A61K9/0053 , A61K9/16 , A61K9/1635 , A61K9/1652 , A61K9/20 , A61K9/2013 , A61K9/2027 , A61K9/2054 , A61K9/2077 , A61K9/2086 , A61K9/2095 , A61K31/485 , B29B9/06 , B29K2033/12 , B29K2105/0085

摘要： A neutral poly(ethyl acrylate, methyl methacrylate) copolymer is employed as a carrier in the manufacture of pharmaceutical formulations containing an active ingredient. The formulations are preferably made by melt extrusion, and can have rubbery characteristics and can exhibit tamper resistance.

摘要翻译： 在制备含有活性成分的药物制剂中使用中性聚（丙烯酸乙酯，甲基丙烯酸甲酯）共聚物作为载体。制剂优选通过熔融挤出制备，并且可以具有橡胶特性并且可表现出抗窜改性。