Method for forecasting the contrast medium flow in a living body

    公开(公告)号:US07477929B2

    公开(公告)日:2009-01-13

    申请号:US11352227

    申请日:2006-02-13

    IPC分类号: A61B6/00 A61B5/05

    CPC分类号: A61B6/504 A61B6/481

    摘要: A method is disclosed for forecasting the contrast medium flow in a living body, in particular in a patient, in which a defined test bolus with a contrast medium is injected, preferably intravenously and with a known injection flow profile, into the body, preferably into a blood vessel. The time concentration profile of the contrast medium is observed and determined over a limited time period with a number of measuring instants at at least one location in the body with the aid of a tomographic method. The time profile of the contrast medium concentration of another contrast medium dose is forecast with the aid of a linear cause/effect formulation from the measured data obtained via the distribution of the contrast medium. The following calculation formula is then used for forecasting the time concentration profile {tilde over (c)}R(t) of the contrast medium at at least one of the previously measured locations of the body: c ~ R ⁡ ( t ) = 1 F T ⁢ ∑ n = na n = ne ⁢ ∫ x = xa x = xe ⁢ ⅆ t ′ ⁢ c ~ R ⁡ ( t + t 0 ⁢ T - n ⁢ ⁢ Δ T - t ′ ) ⁢ b R ′ ⁡ ( t ′ ) .

    Method for forecasting the contrast medium flow in a living body

    公开(公告)号:US20060239917A1

    公开(公告)日:2006-10-26

    申请号:US11352227

    申请日:2006-02-13

    IPC分类号: A61B5/055

    CPC分类号: A61B6/504 A61B6/481

    摘要: A method is disclosed for forecasting the contrast medium flow in a living body, in particular in a patient, in which a defined test bolus with a contrast medium is injected, preferably intravenously and with a known injection flow profile, into the body, preferably into a blood vessel. The time concentration profile of the contrast medium is observed and determined over a limited time period with a number of measuring instants at at least one location in the body with the aid of a tomographic method. The time profile of the contrast medium concentration of another contrast medium dose is forecast with the aid of a linear cause/effect formulation from the measured data obtained via the distribution of the contrast medium. The following calculation formula is then used for forecasting the time concentration profile {tilde over (c)}R(t) of the contrast medium at at least one of the previously measured locations of the body: c ~ R ⁡ ( t ) = 1 F T ⁢ ∑ n = na n = ne ⁢ ∫ x = xa x = xe ⁢ ⅆ t ′ ⁢ c ~ R ⁡ ( t + t 0 ⁢ T - n ⁢   ⁢ Δ T - t ′ ) ⁢ b R ′ ⁡ ( t ′ ) .