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    METHODS AND COMPOSITIONS FOR TREATING HIV-ASSOCIATED DIARRHEA
    5.
    发明申请
    METHODS AND COMPOSITIONS FOR TREATING HIV-ASSOCIATED DIARRHEA 审中-公开
    用于治疗HIV相关性腹泻的方法和组合物

    公开(公告)号：US20140163096A1

    公开(公告)日：2014-06-12

    申请号：US13840861

    申请日：2013-03-15

    申请人： Pam Golden ,  William Forbes ,  Enoch Bortey

    发明人： Pam Golden ,  William Forbes ,  Enoch Bortey

    IPC分类号： A61K31/353

    CPC分类号： A61K31/353

    摘要： Provided herein are methods for treating HIV-associated or highly active antiretroviral therapy (HAART)-associated diarrhea in an HIV positive subject by administering a composition comprising crofelemer to the subject wherein the composition has minimal drug-drug interactions with at least one other compound concurrently administered to the subject to treat an HIV infection. Also provided are methods for treating HIV-associated or highly active antiretroviral therapy (HAART)-associated diarrhea in an HIV positive subject by administering a composition comprising crofelemer to the subject, wherein the composition does not significantly inhibit the activity of at least one other compound concurrently administered to the subject to treat an HIV infection.

    摘要翻译： 本文提供了通过向受试者施用包含消灭者的组合物来治疗HIV阳性受试者的HIV相关或高度活跃的抗逆转录病毒疗法（HAART）相关性腹泻的方法，其中所述组合物同时与至少一种其它化合物同时具有最小的药物 - 药物相互作用 给予受试者治疗HIV感染。 还提供了通过向受试者施用包含灭活剂的组合物来治疗HIV阳性受试者中与HIV相关或高活性抗逆转录病毒疗法（HAART）相关性腹泻的方法，其中所述组合物不显着抑制至少一种其它化合物的活性 同时施用于受试者以治疗HIV感染。