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1.发明申请ACETYLCHOLINESTERASE (ACHE)-DERIVED PEPTIDE AS AN INDUCER OF GRANULOCYTOPOIESIS, USES AND METHODS THEREOF 审中-公开乙酰胆碱酯酶（ACHE）衍生肽作为颗粒细胞的诱导剂，其用途及其方法公开(公告)号：US20110039791A1
公开(公告)日：2011-02-17
申请号：US12889564
申请日：2010-09-24
申请人： Hermona Soreq , Dan Grisaru , Varda Deutsch , Chava Perry , Marjorie Pick
发明人： Hermona Soreq , Dan Grisaru , Varda Deutsch , Chava Perry , Marjorie Pick
CPC分类号： A61K38/465 , C12Y301/01007
摘要： The present invention describes the use of an AChE-R-derived peptide, also known as ARP, as an inducer of hemopoietic cell differentiation and expansion, specifically for the granulocytic population. In addition, the use of ARP as an inducer of thrombopoietin and pro-inflammatory cytokines is also presented. ARP may further be used in the pre-transplant priming of hematopoietic stem cells. Other uses and methods utilizing ARP are also described herein.
摘要翻译： 本发明描述了AChE-R衍生肽（也称为ARP）作为造血细胞分化和扩增的诱导剂，特别是针对粒细胞群体的用途。 此外，还提出了使用ARP作为血小板生成素和促炎细胞因子的诱导剂。 在造血干细胞的移植前引发中还可以使用ARP。 本文还描述了利用ARP的其他用途和方法。
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公开(公告)号：US20070224181A1
公开(公告)日：2007-09-27
申请号：US10589116
申请日：2005-02-10
申请人： Hermona Soreq , Dan Grisaru , Varda Deutsch , Chava Perry , Marjorie Pick
发明人： Hermona Soreq , Dan Grisaru , Varda Deutsch , Chava Perry , Marjorie Pick
CPC分类号： A61K38/465 , C12Y301/01007
摘要： The present invention describes the use of an AChE-R-derived peptide, also known as ARP, as an inducer of hemopoietic cell differentiation and expansion, specifically for the granulocytic population. In addition, the use of ARP as an inducer of thrombopoietin and pro-inflammatory cytokines is also presented. ARP may further be used in the pre-transplant priming of hematopoietic stem cells. Other uses and methods utilizing ARP are also described herein.
摘要翻译： 本发明描述了AChE-R衍生肽（也称为ARP）作为造血细胞分化和扩增的诱导剂，特别是针对粒细胞群体的用途。 此外，还提出了使用ARP作为血小板生成素和促炎细胞因子的诱导剂。 在造血干细胞的移植前引发中还可以使用ARP。 本文还描述了利用ARP的其他用途和方法。
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3.发明授权Acetylcholinesterase (ACHE)-derived peptide as an inducer of granulocytopoiesis, uses and methods thereof 有权乙酰胆碱酯酶（ACHE）衍生肽作为粒细胞生成的诱导剂，其用途及方法公开(公告)号：US07838493B2
公开(公告)日：2010-11-23
申请号：US10589116
申请日：2005-02-10
申请人： Hermona Soreq , Dan Grisaru , Varda Deutsch , Chava Perry , Marjorie Pick
发明人： Hermona Soreq , Dan Grisaru , Varda Deutsch , Chava Perry , Marjorie Pick
IPC分类号： A61K38/00
CPC分类号： A61K38/465 , C12Y301/01007
摘要： The present invention describes the use of an AChE-R-derived peptide, also known as ARP, as an inducer of hemopoietic cell differentiation and expansion, specifically for the granulocytic population. In addition, the use of ARP as an inducer of thrombopoietin and pro-inflammatory cytokines is also presented. ARP may further be used in the pre-transplant priming of hematopoietic stem cells. Other uses and methods utilizing ARP are also described herein.
摘要翻译： 本发明描述了AChE-R衍生肽（也称为ARP）作为造血细胞分化和扩增的诱导剂，特别是针对粒细胞群体的用途。 此外，还提出了使用ARP作为血小板生成素和促炎细胞因子的诱导剂。 在造血干细胞的移植前引发中还可以使用ARP。 本文还描述了利用ARP的其他用途和方法。
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