利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

62 条记录 (耗时 0.034 秒)

    Drug-enhanced adhesion prevention
    2.
    发明授权
    Drug-enhanced adhesion prevention 有权
    药物增强粘附防止

    公开(公告)号：US09066912B2

    公开(公告)日：2015-06-30

    申请号：US10714719

    申请日：2003-11-17

    申请人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61K9/127 ,  A61K31/196 ,  A61K9/50

    CPC分类号： A61K31/196 ,  A61K9/127 ,  A61K9/5031

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Tranilast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括以体积的量向管腔内的组织表面直接给予Tranilast或其类似物 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。

    Drug-enhanced adhesion prevention
    3.
    发明授权
    Drug-enhanced adhesion prevention 有权
    药物增强粘附防止

    公开(公告)号：US08394399B2

    公开(公告)日：2013-03-12

    申请号：US12021546

    申请日：2008-01-29

    申请人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61F2/02

    CPC分类号： A61K9/1647

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Pemirolast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括将Pemirolast或其类似物以体积的数量直接施用于体腔内的组织表面 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。

    Drug-enhanced adhesion prevention
    4.
    发明授权
    Drug-enhanced adhesion prevention 有权
    药物增强粘附防止

    公开(公告)号：US08277831B2

    公开(公告)日：2012-10-02

    申请号：US10780452

    申请日：2004-02-17

    申请人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel E. Young ,  Scott A. Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61F2/02

    CPC分类号： A61K9/1647

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Pemirolast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括将Pemirolast或其类似物以体积的数量直接施用于体腔内的组织表面 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。

    Drug-enhanced adhesion prevention
    5.
    发明申请
    Drug-enhanced adhesion prevention 有权
    药物增强粘附防止

    公开(公告)号：US20050181023A1

    公开(公告)日：2005-08-18

    申请号：US10780452

    申请日：2004-02-17

    申请人： Janel Young ,  Scott Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel Young ,  Scott Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61K9/16 ,  A61K31/519 ,  A61K9/127 ,  A61K9/70

    CPC分类号： A61K9/1647

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Pemirolast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括将Pemirolast或其类似物以体积的数量直接施用于体腔内的组织表面 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。

    DRUG-ENHANCED ADHESION PREVENTION
    7.
    发明申请
    DRUG-ENHANCED ADHESION PREVENTION 有权
    增强粘合剂预防

    公开(公告)号：US20080119494A1

    公开(公告)日：2008-05-22

    申请号：US12021546

    申请日：2008-01-29

    申请人： Janel Young ,  Scott Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel Young ,  Scott Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61K31/519 ,  A61P41/00

    CPC分类号： A61K9/1647

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Pemirolast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括将Pemirolast或其类似物以体积的数量直接施用于体腔内的组织表面 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。

    Drug-enhanced adhesion prevention
    8.
    发明申请
    Drug-enhanced adhesion prevention 有权
    药物增强粘附防止

    公开(公告)号：US20050106229A1

    公开(公告)日：2005-05-19

    申请号：US10714719

    申请日：2003-11-17

    申请人： Janel Young ,  Scott Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    发明人： Janel Young ,  Scott Wadsworth ,  Kevin Cooper ,  Joel Rosenblatt ,  Han Cui

    IPC分类号： A61K9/127 ,  A61K9/50 ,  A61K31/196

    CPC分类号： A61K31/196 ,  A61K9/127 ,  A61K9/5031

    摘要： The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Tranilast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.

    摘要翻译： 本发明包括用于抑制经受外科手术的体腔中的组织表面之间的术后粘连形成的方法，该方法包括以体积的量向管腔内的组织表面直接给予Tranilast或其类似物 并且在有效抑制粘连形成的条件下，以及适用于局部，非全身给药的体内和直接经受外科手术的体腔内组织的输送载体和组合物。

    Compositions for parenteral administration and sustained-release of therapeutic agents
    9.
    发明授权
    Compositions for parenteral administration and sustained-release of therapeutic agents 有权
    用于肠胃外给药和治疗剂缓释的组合物

    公开(公告)号：US07220433B2

    公开(公告)日：2007-05-22

    申请号：US10608507

    申请日：2003-06-27

    申请人： Han Cui ,  Joel Rosenblatt ,  Ram L. Kataria ,  Chuanbin Wu

    发明人： Han Cui ,  Joel Rosenblatt ,  Ram L. Kataria ,  Chuanbin Wu

    IPC分类号： A61K9/16

    CPC分类号： A61K9/5073 ,  A61K47/34

    摘要： The present invention is directed to parenterally-administrable microparticles for providing sustained-release of a therapeutic agent in the body, where the microparticles include a polymeric core containing a therapeutically effective amount of a therapeutic agent disposed therein, a first film encapsulating the core, the first film prepared from a first biodegradable polymer soluble in an appropriate solvent therefore, and a second film encapsulating the core and the first film, the second film prepared from a biodegradable polymer soluble in an appropriate solvent therefore, wherein the first film is insoluble in the solvent used to prepare the second film, and to parenterally-administrable compositions containing such microparticles dispersed in a suitable carrier therefore.

    摘要翻译： 本发明涉及用于在体内提供治疗剂持续释放的肠胃外给药微粒，其中微粒包括含有治疗有效量的治疗剂的聚合物芯，其中包含核心的第一膜， 因此，由可溶于适当溶剂的第一可生物降解聚合物制备的第一膜以及包封芯和第一膜的第二膜，由可溶于适当溶剂的可生物降解的聚合物制备的第二膜，其中第一膜不溶于 因此用于制备第二膜的溶剂，以及含有分散在合适载体中的这种微粒的肠胃外给药组合物。

    Polymer coated microparticles for sustained release
    10.
    发明授权
    Polymer coated microparticles for sustained release 有权
    聚合物涂层微粒用于持续释放

    公开(公告)号：US07101566B2

    公开(公告)日：2006-09-05

    申请号：US10183260

    申请日：2002-06-28

    申请人： Joel Rosenblatt ,  Han Cui ,  Ram L. Kataria ,  Chuanbin Wu

    发明人： Joel Rosenblatt ,  Han Cui ,  Ram L. Kataria ,  Chuanbin Wu

    IPC分类号： A61F13/00 ,  A61F2/00 ,  A61K9/14 ,  A61K9/19

    CPC分类号： A61K9/5031 ,  A61K47/34

    摘要： The present invention is directed to sustained release microparticle formulation for parenteral administration of biologically active substances, especially drugs. More specifically it relates to coated drug containing microparticles, wherein the coating is a synthetic, bioabsorbable, biocompatible polymeric wax that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the polymeric wax having a melting point less than about 70° C., as determined by differential scanning calorimetry.

    摘要翻译： 本发明涉及用于肠胃外给药生物活性物质，特别是药物的持续释放微粒制剂。 更具体地说，它涉及含有包衣药物的微粒，其中涂层是合成的，生物可吸收的生物相容性聚合物蜡，其是多元酸或其衍生物，多元醇和脂肪酸的反应产物，聚合物蜡的熔点较低 如通过差示扫描量热法测定的。