公开(公告)号：US12246316B2

公开(公告)日：2025-03-11

申请号：US17522571

申请日：2021-11-09

Applicant: HighRes Biosolutions, Inc.

Inventor： Ulysses Gilchrist ,  Robert Connors

IPC: B01L3/02 ,  B01L3/00 ,  G01N35/10

Abstract: An auto-pipetting apparatus includes a dispensing head with at least one pipetting tip mandrel having an elongated stud body with an insertion end. The at least one pipetting tip mandrel mates with a pipetting tip. A first adjustable seal, disposed on the elongated stud body, and a second adjustable seal, disposed on the elongated stud body, seal the pipetting tip mated to the at least one pipetting tip mandrel. The first adjustable seal defines a snub surface. The snub surface effects a substantially continuous circumferential contact seal with radially impinging contact between the pipetting tip and the at least one pipetting tip mandrel. The second adjustable seal is adjustable between a disengaged position and an engaged position and effects a releasable grip and another substantially continuous circumferential contact seal between the pipetting tip and the at least one pipetting tip mandrel around the pipetting tip.

公开(公告)号：US20220118437A1

公开(公告)日：2022-04-21

申请号：US17522571

申请日：2021-11-09

Applicant: HighRes Biosolutions, Inc.

Inventor： Ulysses Gilchrist ,  Robert Connors

IPC: B01L3/02 ,  G01N35/10

Abstract: An auto-pipetting apparatus includes a dispensing head with at least one pipetting tip mandrel having an elongated stud body with an insertion end. The at least one pipetting tip mandrel mates with a pipetting tip. A first adjustable seal, disposed on the elongated stud body, and a second adjustable seal, disposed on the elongated stud body, seal the pipetting tip mated to the at least one pipetting tip mandrel. The first adjustable seal defines a snub surface. The snub surface effects a substantially continuous circumferential contact seal with radially impinging contact between the pipetting tip and the at least one pipetting tip mandrel. The second adjustable seal is adjustable between a disengaged position and an engaged position and effects a releasable grip and another substantially continuous circumferential contact seal between the pipetting tip and the at least one pipetting tip mandrel around the pipetting tip.

公开(公告)号：US11167282B2

公开(公告)日：2021-11-09

申请号：US15883843

申请日：2018-01-30

Applicant: HighRes Biosolutions, Inc.

Inventor： Ulysses Gilchrist ,  Robert Connors

IPC: B01L3/02 ,  G01N35/10

Abstract: An auto-pipetting apparatus includes a dispensing head with at least one pipetting tip mandrel having an elongated stud body with an insertion end. The at least one pipetting tip mandrel mates with a pipetting tip. A first adjustable seal, disposed on the elongated stud body, and a second adjustable seal, disposed on the elongated stud body, seal the pipetting tip mated to the at least one pipetting tip mandrel. The first adjustable seal defines a snub surface. The snub surface effects a substantially continuous circumferential contact seal with radially impinging contact between the pipetting tip and the at least one pipetting tip mandrel. The second adjustable seal is adjustable between a disengaged position and an engaged position and effects a releasable grip and another substantially continuous circumferential contact seal between the pipetting tip and the at least one pipetting tip mandrel around the pipetting tip.