摘要:
This invention relates to the provision of novel aminomethyl-substituted thiazolobenzimidazole derivatives represented by the following general formula (I) or a salt thereof.The aforementioned derivative or a salt thereof has a metabotropic glutamate receptor action and excellent oral activity and is therefore useful as a medicament. (In the formula, R1: an oxygen-containing saturated hetero ring or the like, Alk1: a lower alkylene, m: 0 or 1, Alk2: a lower alkylene which may be substituted with oxo group, n: 0 or 1, X: a bond, O, S or NR5, R3: H or the like, and R2, R4, R5, R6 and R7: the same or different from one another and each represents H or the like. Provided that R3 does not represent a lower alkyl or a halogeno-lower alkyl when X is a bond and n is 1. Also, R4 represents a group other than Me when m is 1, R1 is OH or OMe and Alk1 is a C1-3 alkylene, and further 1) when X is a bond, n is 1 and R3 is H, or 2) when X is a bond, n is 0 and R3 is cyclohexane.)
摘要:
This invention relates to the provision of novel aminomethyl-substituted thiazolobenzimidazole derivatives represented by the following general formula (I) or a salt thereof. The aforementioned derivative or a salt thereof has a metabotropic glutamate receptor action and excellent oral activity and is therefore useful as a medicament. (In the formula, R1: an oxygen-containing saturated hetero ring or the like, Alk1: a lower alkylene, m: 0 or 1, Alk2: a lower alkylene which may be substituted with oxo group, n: 0 or 1, X: a bond, O, S or NR5, R3: H or the like, and R2, R4, R5, R6 and R7: the same or different from one another and each represents H or the like. Provided that R3 does not represent a lower alkyl or a halogeno-lower alkyl when X is a bond and n is 1. Also, R4 represents a group other than Me when m is 1, R1 is OH or OMe and Alk1 is a C1-3 alkylene, and further 1) when X is a bond, n is 1 and R3 is H, or 2) when X is a bond, n is 0 and R3 is cyclohexane.)
摘要:
This invention relates to pharmaceuticals for neuropathic pains comprising an mGluR1 receptor antagonist for systemic administration. Drugs efficacious in treating various neuropathic pain can be provided by the invention.
摘要:
A display apparatus includes a plurality of first scan lines for analog display, which are arranged along one direction on a substrate; a plurality of second scan lines for digital display, which are arranged along this one direction on the substrate; a plurality of data signal lines which are arranged in a direction intersecting the one direction; a plurality of display pixels which are selected by a predetermined scan line selection signal concerning the first scan line and the second scan line and to which an image signal from the data signal lines is supplied, the plurality of display pixels being arranged in a matrix on the substrate; a first display circuit for the analog display, which is connected to the first scan line via a first switch circuit which operates by means of the scan line selection signal, and which is disposed in the display pixel, the first display circuit sequentially supplying the image signal which is sequentially input to a pixel electrode of the display pixel, a second display circuit for the digital display, which is connected to the second scan line via a second switch circuit which operates by means of the scan line selection signal, and which is disposed in the display pixel, the second display circuit including a holding circuit which holds the image signal and supplying a voltage in accordance with the signal held by the holding circuit to the pixel electrode; and a mode switching circuit for performing mode switching between an analog display mode in which the first display circuit operates and a digital display mode in which the second display circuit operates, in accordance with a mode switching signal.
摘要:
A semiconductor circuit includes a first circuit block, a second circuit block, and power wiring lines that supply a plurality of reference potentials. The first circuit block and the second circuit block are connected to a common power wiring line that is one of the power wiring lines and supplies a common reference potential. A width of the common power wiring line in the first circuit block is smaller than a width of the common power wiring line in the second circuit block.
摘要:
A method of driving a liquid crystal display device includes a plurality of scanning lines, a plurality of data lines arranged to intersect the plurality of scanning lines, a plurality of pixel electrodes arranged in correspondence with the intersections between the plurality of scanning lines and the plurality of data lines, a plurality of pixel switching elements for supplying the signals of the data lines to the pixel electrodes based on the signals of the scanning lines, and an opposed electrode facing the pixel electrodes. The plurality of scanning lines are supplied with respective timings to apply any one of a selection potential and a non-selection potential to the pixel switching elements, the opposed electrode is inversion-driven between a first potential and a second potential, and at least one of the plurality of scanning lines has the selection potential at a common inversion timing when the opposed electrode is inverted from the first potential to the second potential.
摘要:
The present invention provides a small-sized electrostatic condenser type pressure sensor having high assembly accuracy but no dispersion in a detection accuracy, and a method for manufacturing the pressure sensor. An annular spacer is mounted on the confronting faces of substrates around flat electrodes, and a frit is mounted around the spacer and is made of a material having a lower softening or melting point than that of the spacer.
摘要:
A semiconductor circuit includes a first circuit block, a second circuit block, and power wiring lines that supply a plurality of reference potentials. The first circuit block and the second circuit block are connected to a common power wiring line that is one of the power wiring lines and supplies a common reference potential. A width of the common power wiring line in the first circuit block is smaller than a width of the common power wiring line in the second circuit block.
摘要:
A semiconductor circuit includes a first circuit block, a second circuit block, and power wiring lines that supply a plurality of reference potentials. The first circuit block and the second circuit block are connected to a common power wiring line that is one of the power wiring lines and supplies a common reference potential. A width of the common power wiring line in the first circuit block is smaller than a width of the common power wiring line in the second circuit block.
摘要:
A method of driving a liquid crystal display device includes a plurality of scanning lines, a plurality of data lines arranged to intersect the plurality of scanning lines, a plurality of pixel electrodes arranged in correspondence with the intersections between the plurality of scanning lines and the plurality of data lines, a plurality of pixel switching elements for supplying the signals of the data lines to the pixel electrodes based on the signals of the scanning lines, and an opposed electrode facing the pixel electrodes. The plurality of scanning lines are supplied with respective timings to apply any one of a selection potential and a non-selection potential to the pixel switching elements, the opposed electrode is inversion-driven between a first potential and a second potential, and at least one of the plurality of scanning lines has the selection potential at a common inversion timing when the opposed electrode is inverted from the first potential to the second potential.