Optical resolution method of (.+-.)-3,4-dihydroxybutanoic acid
    1.
    发明授权
    Optical resolution method of (.+-.)-3,4-dihydroxybutanoic acid 失效
    (+/-) - 3,4-二羟基丁酸的光学拆分方法

    公开(公告)号:US6069270A

    公开(公告)日:2000-05-30

    申请号:US972145

    申请日:1997-11-17

    CPC分类号: C07C51/487

    摘要: An optical resolution method of (.+-.)-3,4-dihydroxybutanoic acid, by reacting (.+-.)-3,4-dihydroxybutanoic acid with an optically active primary amine or secondary amine. Also a method for producing optically active 3-hydroxy-.gamma.-butyrolactone, by reacting (.+-.)-3,4-dihydroxybutanoic acid with an optically active primary amine or secondary amine for optical resolution, and ring closing the resulting optically active 3,4-dihydroxybutanoic acid.

    摘要翻译: (+/-) - 3,4-二羟基丁酸的光学拆分方法,通过使(+/-) - 3,4-二羟基丁酸与光学活性伯胺或仲胺反应。 还可以通过使(+/-) - 3,4-二羟基丁酸与光学活性伯胺或仲胺反应以进行光学拆分来制备光学活性的3-羟基-γ-丁内酯的方法,并将所得的光学活性3 ,4-二羟基丁酸。