公开(公告)号：US07323674B2

公开(公告)日：2008-01-29

申请号：US11506204

申请日：2006-08-18

申请人： Hisaki Kato ,  Hideki Shimoi ,  Kazuya Horiuchi ,  Toshiaki Ushizu

发明人： Hisaki Kato ,  Hideki Shimoi ,  Kazuya Horiuchi ,  Toshiaki Ushizu

IPC分类号： H01J40/14 ,  H01J43/00

CPC分类号： H01J43/22 ,  H01J40/14 ,  H01J43/045

摘要： The present invention relates to a photodetector that has a structure capable of realizing a wide range gain adjustment for each of electron multiplier channels respectively assigned to a plurality of light incidence regions of a multi-anode multiplier. The photodetector comprises a multi-anode photomultiplier, and a bleeder circuit unit. The multi-anode multiplier has a dynode unit constituted by N (an integer or no less than 3) dynode plates, and n-th (an integer of no less then 2) dynode plate is constituted by a plurality of control plates respectively corresponding to the multiplier channels. The bleeder circuit unit has a primary section setting each potential of a first to (n−1)-th and (n+1)-th to N-th dynode plates, and a secondary section for individually setting a potential of each control plate at any potential within the range wider than a potential difference between the (n−1)-th and (n+1) dynode plates. By expanding the potential setting range for the control plates rather than the potential difference between the dynode plates adjacent to the n-th dynode plate, the gain of each electron multiplier channel can be controlled by two digits or more.

摘要翻译： 本发明涉及一种具有能够实现对分别分配给多阳极倍增器的多个入射区域的每个电子倍增器通道的宽范围增益调整的结构的光电检测器。 光电检测器包括多阳极光电倍增管和泄放电路单元。 多阳极倍增器具有由N（整数或不小于3）倍增极板构成的倍增电极单元，并且第n（不小于2的整数）倍增极板由分别对应于 乘数通道。 泄放电路单元具有设定第一至第（n-1）和第（n + 1）至第N倍增电极板的每个电位的主要部分，以及用于单独设置每个控制板的电位的次级部分 在比第（n-1）和（n + 1）倍增极板之间的电位差宽的范围内的任何电位。 通过扩大控制板的电位设置范围，而不是与第n倍增极板相邻的倍增极板之间的电位差，每个电子倍增器通道的增益可以被控制在两位以上。

公开(公告)号：US07115854B1

公开(公告)日：2006-10-03

申请号：US11188215

申请日：2005-07-25

申请人： Hisaki Kato ,  Hideki Shimoi ,  Kazuya Horiuchi ,  Toshiaki Ushizu

发明人： Hisaki Kato ,  Hideki Shimoi ,  Kazuya Horiuchi ,  Toshiaki Ushizu

IPC分类号： H01J40/14 ,  H01J43/00

CPC分类号： H01J43/22

摘要： The present invention relates to a photomultiplier that can realize a gain adjustment for each of electron multiplier channels respectively assigned to a plurality of light incidence regions in a more compact structure. The photomultiplier has a sealed container, and a photocathode, a dynode unit, and plurality of anodes prepared for electron multiplier channels are housed in the sealed container. The dynode unit is constituted by N (an integer or no less than 3) dynode plates, each provided with an electron multiplier hole for the associated channel, concerning all channels. In particular, the n-th (an integer of no less then 2) dynode plate is constituted by a plurality of control plates, each having an electron multiplier hole for the associated channel, and electrically and physically separated from the others. These control plates are supported in state of being supported, via insulators, by the (n−1)-th dynode plate and the (n+1)-th dynode plate.

摘要翻译： 本发明涉及一种光电倍增器，其可以以更紧凑的结构实现分配给多个光入射区域的每个电子倍增器通道的增益调整。 光电倍增管具有密封容器，并且为了电子倍增器通道而制备的光电阴极，倍增极单元和多个阳极容纳在密封容器中。 倍增电极单元由关于所有通道的N（整数或不小于3个）的倍增极板构成，每个极化极板均具有用于相关通道的电子倍增器孔。 特别地，第n（不小于2的整数）倍增极板由多个控制板构成，每个控制板具有用于相关通道的电子倍增器孔，并且与其他电气和物理分离。 这些控制板通过第（n-1）倍增极板和第（n + 1）倍增极板通过绝缘体被支撑的状态。

公开(公告)号：US20070040096A1

公开(公告)日：2007-02-22

申请号：US11506204

申请日：2006-08-18

申请人： Hisaki Kato ,  Hideki Shimoi ,  Kazuya Horiuchi ,  Toshiaki Ushizu

发明人： Hisaki Kato ,  Hideki Shimoi ,  Kazuya Horiuchi ,  Toshiaki Ushizu

IPC分类号： H01J40/14

CPC分类号： H01J43/22 ,  H01J40/14 ,  H01J43/045

摘要： The present invention relates to a photodetector that has a structure capable of realizing a wide range gain adjustment for each of electron multiplier channels respectively assigned to a plurality of light incidence regions of a multi-anode multiplier. The photodetector comprises a multi-anode photomultiplier, and a bleeder circuit unit. The multi-anode multiplier has a dynode unit constituted by N (an integer or no less than 3) dynode plates, and n-th (an integer of no less then 2) dynode plate is constituted by a plurality of control plates respectively corresponding to the multiplier channels. The bleeder circuit unit has a primary section setting each potential of a first to (n−1)-th and (n+1)-th to N-th dynode plates, and a secondary section for individually setting a potential of each control plate at any potential within the range wider than a potential difference between the (n−1)-th and (n+1) dynode plates. By expanding the potential setting range for the control plates rather than the potential difference between the dynode plates adjacent to the n-th dynode plate, the gain of each electron multiplier channel can be controlled by two digits or more.

摘要翻译： 本发明涉及一种具有能够实现对分别分配给多阳极倍增器的多个入射区域的每个电子倍增器通道的宽范围增益调整的结构的光电检测器。 光电检测器包括多阳极光电倍增管和泄放电路单元。 多阳极倍增器具有由N（整数或不小于3）倍增极板构成的倍增电极单元，并且第n（不小于2的整数）倍增极板由分别对应于 乘数通道。 泄放电路单元具有设定第一至第（n-1）和第（n + 1）至第N倍增电极板的每个电位的初级部分，以及用于单独设置每个控制板的电位的次级部分 在比第（n-1）和（n + 1）倍增极板之间的电位差宽的范围内的任何电位。 通过扩大控制板的电位设置范围，而不是与第n倍增极板相邻的倍增极板之间的电位差，每个电子倍增器通道的增益可以被控制在两位以上。

公开(公告)号：US20050180885A1

公开(公告)日：2005-08-18

申请号：US11030319

申请日：2005-01-07

申请人： Naohisa Tateishi ,  Yuji Masuda ,  Toshiaki Ushizu

发明人： Naohisa Tateishi ,  Yuji Masuda ,  Toshiaki Ushizu

IPC分类号： G01N15/14 ,  G01N21/05 ,  G01N21/49 ,  G01N33/00

CPC分类号： G01N15/1404 ,  G01N2015/1409

摘要： The present invention relates to a sheath flow cell cuvette and the like provided with a structure to effectively prevent relative positional fluctuation between component members. The said sheath flow cell cuvette comprises a chamber portion comprised of a resin and an orifice portion comprised of a glass material. One end of the orifice portion is buried in the chamber portion, and at this buried part, a latching structure to prevent the orifice portion from shifting with respect to the chamber portion is provided. A cell suspension fluid of a measuring object is injected at high pressure from the chamber portion toward the orifice portion while being surrounded by a sheath fluid. At this time, although an extruding pressure along a flowing direction of the cell suspension fluid is exerted on the orifice portion, since a relative positional fluctuation between the chamber portion and orifice portion is avoided by an action of the latching structure covered with the resin of a part of the chamber portion, a laminar flow condition between the cell suspension fluid and sheath fluid is stably maintained.

摘要翻译： 本发明涉及一种具有有效防止部件间的相对位置偏移的结构的护套流通池试管等。 所述鞘流动池比色皿包括由树脂构成的室部分和由玻璃材料组成的孔口部分。 孔部分的一端被埋在腔室部分中，并且在这个掩埋部分设置有用于防止孔口部分相对于腔室部分移动的闩锁结构。 测量对象的细胞悬浮液从腔室部分朝向孔口部分以高压被注入，同时被鞘液包围。 此时，虽然沿着细胞悬浮液的流动方向的挤压力被施加在孔口部分上，但是通过用树脂覆盖的闩锁结构的作用来避免腔室部分和孔口部分之间的相对位置波动 室部分的一部分，细胞悬浮液和鞘液之间的层流状态得到稳定保持。