公开(公告)号：US20050003001A1

公开(公告)日：2005-01-06

申请号：US10491887

申请日：2002-10-30

申请人： Hisami Yamaguchi ,  Shuji Saka ,  Takao Ueda

发明人： Hisami Yamaguchi ,  Shuji Saka ,  Takao Ueda

IPC分类号： A61K9/16 ,  A61K9/20 ,  A61K9/48 ,  A61K31/428 ,  A61K31/554 ,  A61K47/20 ,  A61K47/26 ,  A61K47/34 ,  A61K47/36 ,  A61K47/38 ,  A61K9/14

CPC分类号： A61K31/554 ,  A61K9/1617 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/2054 ,  A61K31/428

摘要： The present invention is to provide a method for improving the dissolution of a poorly dispersible medicament and that is achieved by preparing a granulated product where a floating agent is added to the poorly dispersible medicament.

摘要翻译： 本发明提供一种改善不良分散药物的溶解的方法，其通过制备其中将浮剂加入到难分散药物中的制粒产品来实现。

公开(公告)号：US06509003B2

公开(公告)日：2003-01-21

申请号：US09764263

申请日：2001-01-19

申请人： Toshiaki Irie ,  Kiyoshi Fukushi ,  Hiroki Namba ,  Masaomi Iyo ,  Nobuo Ikota ,  Shinichiro Nagatsuka ,  Takao Ueda ,  Masaru Nishiura ,  Keizo Takatoku ,  Isamu Yomoda

发明人： Toshiaki Irie ,  Kiyoshi Fukushi ,  Hiroki Namba ,  Masaomi Iyo ,  Nobuo Ikota ,  Shinichiro Nagatsuka ,  Takao Ueda ,  Masaru Nishiura ,  Keizo Takatoku ,  Isamu Yomoda

IPC分类号： A61K5104

CPC分类号： C07D211/46 ,  A61K51/0455 ,  C07D211/42

摘要： The present invention relates to N-alkylpiperidine derivatives represented by general formula (1) or (2); wherein R1 represents optionally fluorinated lower alkyl; R2 represents lower alkyl; and R3 represents alkenyl substituted at the 1-position with hydroxy, lower alkoxy, lower alkoxyalkyloxy, lower alkoxyalkyloxyalkyloxy, or lower alkanoyloxy and substituted at the end with radioactive iodine, or alkenyloxymethyl substituted at the end with a radioactive iodine reagent containing the same for assaying central local AchE activity; a method for assaying the central local AchE activity; and labeled precursors of the above compounds. After easily passing through the blood-brain barrier, these compounds are hydrolyzed specifically by AchE in the brain into alcohols, which are then captured by the brain. In contrast, alcohols formed outside the brain do not migrate into the brain. The compounds of the invention emit &ggr;-rays at an appropriate energy level. These characteristics make the compounds highly useful as tracers for SPECT in assaying the central AchE activity.

摘要翻译： 本发明涉及由通式（1）或（2）表示的N-烷基哌啶衍生物，其中R 1表示任意氟化的低级烷基; R2代表低级烷基; R 3表示在1-位被羟基，低级烷氧基，低级烷氧基烷氧基，低级烷氧基烷氧基氧基或低级烷酰氧基取代的链烯基，末端用放射性碘取代，或末端用含有该取代基的放射性碘试剂取代的链烯氧基甲基 中央地方AchE活动; 测定中心局部AchE活性的方法; 和上述化合物的标记前体。 在容易通过血脑屏障之后，这些化合物被脑中的AchE特异性水解成醇，然后被脑捕获。 相比之下，形成在脑外的醇不会迁移到大脑中。 本发明的化合物以适当的能级发射γ射线。 这些特征使得化合物在测定中枢AchE活性时作为SPECT的示踪剂非常有用。

公开(公告)号：US5609976A

公开(公告)日：1997-03-11

申请号：US529642

申请日：1995-09-18

申请人： Takao Ueda ,  Yoshihisa Takizawa

发明人： Takao Ueda ,  Yoshihisa Takizawa

IPC分类号： H01M2/16 ,  H01M2/18 ,  H01M10/30

CPC分类号： H01M2/162 ,  H01M10/30 ,  H01M2300/0014 ,  Y02E60/124

摘要： The alkaline storage battery comprises a positive electrode, a negative electrode, a separator, and alkaline electrolyte. The separator is a single layer of synthetic fiber non-woven fabric. Treating the separator to increase either the amount of fiber interconnection at the surface or the amount the fibers are broken apart at the surface or both improves separator strength without sacrificing permeability. This prevents internal short circuits, reduces internal pressure, and significantly improves battery lifetime.

摘要翻译： 碱性蓄电池包括正极，负极，隔板和碱性电解质。 隔板是单层合成纤维无纺布。 处理分离器以增加表面处的纤维互连量或者在表面处分裂纤维的量，或者两者均改善分离器的强度而不牺牲渗透性。 这可以防止内部短路，降低内部压力，并显着提高电池寿命。

公开(公告)号：US06701682B2

公开(公告)日：2004-03-09

申请号：US09977706

申请日：2001-10-16

申请人： Yoichi Ando ,  Kenji Nose ,  Takao Ueda ,  Kiminori Mouri ,  Kyoto Akiyama

发明人： Yoichi Ando ,  Kenji Nose ,  Takao Ueda ,  Kiminori Mouri ,  Kyoto Akiyama

IPC分类号： E04H100

CPC分类号： G06Q10/10

摘要： A workspace system includes a working region and a plurality of work surfaces or desktops placed in the working region. The working region provides a first environment suitable for a right hemisphere-dominant job, a second environment suitable for a left hemisphere-dominant job, a third environment different from the first and the second environments, and a seating area in which a job performer takes a seat. Accordingly, the desktops may include a first desktop for the first environment, a second desktop for the second environment, and a third desktop for the third environment. The three working environments are arranged about the seating area. The first, the second and the third desktops are different in e.g. feel, material, shape and color from each other.

摘要翻译： 工作空间系统包括工作区域和放置在工作区域中的多个工作表面或桌面。 工作区域提供适合于半球占主导地位的第一环境，适合左半球主导工作的第二环境，与第一和第二环境不同的第三环境，以及工作执行者所在的休息区 座位。 因此，桌面可以包括用于第一环境的第一桌面，用于第二环境的第二桌面，以及用于第三环境的第三桌面。 三个工作环境安排在休息区。 第一，第二和第三台面在例如 感觉，材质，形状和颜色。

公开(公告)号：US06556768B1

公开(公告)日：2003-04-29

申请号：US08993993

申请日：1997-12-18

申请人： Yasuhisa Nakajima ,  Takao Ueda ,  Kenji Hamamoto ,  Nobukazu Sugiyama

发明人： Yasuhisa Nakajima ,  Takao Ueda ,  Kenji Hamamoto ,  Nobukazu Sugiyama

IPC分类号： H04N570

CPC分类号： H04N21/4312 ,  G11B15/023 ,  G11B15/07 ,  G11B15/17 ,  G11B23/08714 ,  G11B27/105 ,  G11B27/107 ,  G11B27/11 ,  G11B27/34 ,  G11B33/10 ,  G11B2220/213 ,  G11B2220/2512 ,  G11B2220/2525 ,  G11B2220/2529 ,  G11B2220/2545 ,  G11B2220/2562 ,  G11B2220/65 ,  G11B2220/655 ,  G11B2220/657 ,  G11B2220/90 ,  H04N5/445 ,  H04N5/782 ,  H04N5/85 ,  H04N21/4314 ,  H04N21/4325 ,  H04N21/4334 ,  H04N21/443 ,  H04N21/47214 ,  H04N21/482

摘要： A recording/reproducing apparatus (e.g., VTR) includes capability to exchange information with a storage apparatus such as a memory card mounted on a recording medium assembly (e.g., cassette). When the cassette is inserted into a compartment in the compartment in a VTR, a switch in the VTR is pushed by the case of the cassette, detecting the insertion of the cassette into the compartment. At that time, a signal indicating the insertion of the cassette into the compartment is supplied to a microcomputer from the switch. Notified by the signal, the microcomputer issues a command to a reader/writer, requesting the reader/writer to read out information pertaining to data recorded on the cassette from the memory card mounted on the cassette for recording the data through an antenna. With the cassette located outside the compartment, on the other hand, the microcomputer issues a command to a reader/writer, requesting the reader/writer to read out the information from the memory card through another antenna.

摘要翻译： 记录/再现装置（例如，VTR）包括与诸如安装在记录介质组件（例如，盒式磁带）上的存储卡的存储装置交换信息的能力。 当盒式录像带插入到VTR中的隔室中时，VTR中的开关被盒子的壳体推动，检测到盒子插入隔间。 此时，指示将盒插入隔间的信号从开关提供给微型计算机。 通过信号通知，微机向读写器发出命令，请求读/写器从安装在盒上的存储卡读出与记录在盒上的数据有关的信息，用于通过天线记录数据。 另一方面，当盒子位于隔间外部时，微型计算机向读写器发出命令，请求读/写器通过另一天线从存储卡中读出信息。

公开(公告)号：US06306882B1

公开(公告)日：2001-10-23

申请号：US09424868

申请日：1999-12-08

申请人： Toshiaki Irie ,  Kiyoshi Fukushi ,  Hiroki Namba ,  Masaomi Iyo ,  Nobuo Ikota ,  Shinichiro Nagatsuka ,  Takao Ueda ,  Masaru Nishiura ,  Keizo Takatoku ,  Isamu Yomoda

发明人： Toshiaki Irie ,  Kiyoshi Fukushi ,  Hiroki Namba ,  Masaomi Iyo ,  Nobuo Ikota ,  Shinichiro Nagatsuka ,  Takao Ueda ,  Masaru Nishiura ,  Keizo Takatoku ,  Isamu Yomoda

IPC分类号： A61K31445

CPC分类号： C07D211/46 ,  A61K51/0455 ,  C07D211/42

摘要： The present invention relates to N-alkylpiperidine derivatives represented by general formula (1) or (2); wherein R1 represents optionally fluorinated lower alkyl; R2 represents lower alkyl; and R3 represents alkenyl substituted at the 1-position with hydroxy, lower alkoxy, lower alkoxyalkyloxy, lower alkoxyalkyloxyalkyloxy, or lower alkanoyloxy and substituted at the end with radioactive iodine, or alkenyloxymethyl substituted at the end with a radioactive iodine reagent containing the same for assaying central local AchE activity; a method for assaying the central local AchE activity; and labeled precursors of the above compounds. After easily passing through the blood-brain barrier, these compounds are hydrolyzed specifically by AchE in the brain into alcohols, which are then captured by the brain. In contrast, alcohols formed outside the brain do not migrate into the brain. The compounds of the invention emit &ggr;-rays at an appropriate energy level. These characteristics make the compounds highly useful as tracers for SPECT in assaying the central AchE activity.

摘要翻译： 本发明涉及由通式（1）或（2）表示的N-烷基哌啶衍生物，其中R 1表示任意氟化的低级烷基; R2代表低级烷基; R 3表示在1-位被羟基，低级烷氧基，低级烷氧基烷氧基，低级烷氧基烷氧基氧基或低级烷酰氧基取代的链烯基，末端用放射性碘取代，或末端用含有该取代基的放射性碘试剂取代的链烯氧基甲基 中央地方AchE活动; 测定中心局部AchE活性的方法; 和上述化合物的标记前体。 在容易通过血脑屏障之后，这些化合物被脑中的AchE特异性水解成醇，然后被脑捕获。 相比之下，形成在脑外的醇不会迁移到大脑中。 本发明的化合物以适当的能级发射γ射线。 这些特征使得化合物在测定中枢AchE活性时作为SPECT的示踪剂非常有用。

公开(公告)号：US4916831A

公开(公告)日：1990-04-17

申请号：US265701

申请日：1988-11-01

申请人： Mitsuru Yasumura ,  Atsuo Ohike ,  Takao Ueda ,  Masayoshi Aoki ,  Tomio Suzuki ,  Makoto Horiai

发明人： Mitsuru Yasumura ,  Atsuo Ohike ,  Takao Ueda ,  Masayoshi Aoki ,  Tomio Suzuki ,  Makoto Horiai

IPC分类号： F26B5/04 ,  F26B7/00 ,  F26B11/04 ,  F26B11/02

CPC分类号： F26B11/049 ,  F26B5/04

摘要： A rotary dryer for drying and mixing particulate material, includes a shell having a pair of conical portions and provided with a jacket to which a hot fluid may be fed, the shell defining a chamber for the material to be dried and mixed. An air-tight closure for the chamber is provided with a jacket to which hot fluid may be fed and through which the material is charged and discharged. A rotary tube shaft extends horizontally from one end of the shell and along the horizontal axis of the shell, the rotary tube shaft being sheathed by a rotary joint pipe equipped with a bearing rotatably supporting the rotary tube shaft. The rotary tube shaft is provided with a plurality of communication paths which communicate with charge/discharge ports located on the rotary joint pipe during rotation of the rotary tube shaft in the rotary joint pipe, the communication paths connecting the jackets of the shell and the closure for feeding the hot fluid. An air nozzle is disposed along the internal wall of the shell and a stirrer including a rotational mixing blade are located within the shell to agitate the material, the stirrer being supported by the wall of the shell. A feeder pipe is air-tightly inserted in the rotary tube shaft, sheathing and evacuating pipe to communicate with a vacuum line and an air supply pipe connected to said air nozzle.