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公开(公告)号:US20160091485A1
公开(公告)日:2016-03-31
申请号:US14785594
申请日:2014-04-11
申请人: Ho Man CHAN , Veronica GIBAJA , Kristy HAAS , Jacob JAFFE , Mariela JASKELIOFF , Frank STEGMEIER , Wei QI , THE BROAD INSTITUTE, INC.
发明人: Ho Man CHAN , Veronica GIBAJA , Kristy HAAS , Jacob JAFFE , Mariela JASKELIOFF , Frank Peter STEGMEIER , Wei QI
IPC分类号: G01N33/50
CPC分类号: G01N33/5011 , G01N33/57426 , G01N33/57484 , G01N2560/00 , G01N2800/52
摘要: The invention provides methods of detecting an EZH2 mutation and associated epigenetic markers in a cancer cell, methods cancer diagnosis and methods of screening for EZH2 inhibitors.
摘要翻译: 本发明提供检测癌细胞中EZH2突变和相关表观遗传标记的方法,方法癌症诊断和EZH2抑制剂筛选方法。