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11 条记录 (耗时 0.057 秒)

    PHARMACEUTICAL COMPOSITIONS AND SALTS OF A 1,2,4-OXADIAZOLE BENZOIC ACID
    7.
    发明申请
    PHARMACEUTICAL COMPOSITIONS AND SALTS OF A 1,2,4-OXADIAZOLE BENZOIC ACID 有权
    1,2,4-氧代噻唑酸的药物组合物和盐

    公开(公告)号：US20170066730A1

    公开(公告)日：2017-03-09

    申请号：US15123309

    申请日：2015-03-05

    申请人： PTC Therapeutics, Inc.

    发明人： Marla L. WEETALL ,  Ellen WELCH ,  Mandar V. DALI ,  James TAKASUGI

    IPC分类号： C07D271/06 ,  A61K31/4245 ,  A61K9/00

    CPC分类号： C07D271/06 ,  A61K9/0048 ,  A61K31/4245

    摘要： Provided herein are pharmaceutical compositions, which comprise a 1,2,4-oxadiazole benzoic acid or a pharmaceutically acceptable salt thereof. Further provided herein are certain pharmaceutically acceptable salts of a 1,2,4-oxadiazole benzoic acid and methods for making the same. Further provided herein are methods of treating or preventing a disease associated with a nonsense mutation or a premature stop codon, comprising administering such pharmaceutical compositions or pharmaceutically acceptable salts to a patient having a disease associated with a nonsense mutation or a premature stop codon.

    摘要翻译： 本文提供了包含1,2,4-恶二唑苯甲酸或其药学上可接受的盐的药物组合物。 本文还提供了1,2,4-恶二唑苯甲酸的某些药学上可接受的盐及其制备方法。 本文还提供了治疗或预防与无义突变或早产终止密码子相关的疾病的方法，包括向具有与无义突变相关的疾病或早产终止密码子的患者施用此类药物组合物或药学上可接受的盐。

    PHARMACEUTICAL COMPOSITIONS AND SALTS OF A 1,2,4-OXADIAZOLE BENZOIC ACID
    10.
    发明申请
    PHARMACEUTICAL COMPOSITIONS AND SALTS OF A 1,2,4-OXADIAZOLE BENZOIC ACID 审中-公开

    公开(公告)号：US20190152931A1

    公开(公告)日：2019-05-23

    申请号：US16251318

    申请日：2019-01-18

    申请人： PTC Therapeutics, Inc.

    发明人： Marla L. WEETALL ,  Ellen WELCH ,  Mandar V. DALI ,  James TAKASUGI

    IPC分类号： C07D271/06 ,  A61K9/00 ,  A61K31/4245

    摘要： Provided herein are pharmaceutical compositions, which comprise a 1,2,4-oxadiazole benzoic acid or a pharmaceutically acceptable salt thereof. Further provided herein are certain pharmaceutically acceptable salts of a 1,2,4-oxadiazole benzoic acid and methods for making the same. Further provided herein are methods of treating or preventing a disease associated with a nonsense mutation or a premature stop codon, comprising administering such pharmaceutical compositions or pharmaceutically acceptable salts to a patient having a disease associated with a nonsense mutation or a premature stop codon.