公开(公告)号：US08562673B2

公开(公告)日：2013-10-22

申请号：US12886975

申请日：2010-09-21

申请人： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

发明人： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

IPC分类号： A61F2/24

CPC分类号： A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008

摘要： A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

公开(公告)号：US20110098804A1

公开(公告)日：2011-04-28

申请号：US12886975

申请日：2010-09-21

申请人： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

发明人： Hubert Yeung ,  John Shanahan ,  Joshua Dwork ,  Adam Shipley ,  Jeffrey Allen ,  Susheel Deshmukh ,  Kishore Udipi ,  Ya Guo

IPC分类号： A61F2/24

CPC分类号： A61F2/2436 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2002/9528 ,  A61F2002/9534 ,  A61F2220/005 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/008

摘要： A percutaneous stented valve delivery device including an inner shaft, a sheath, and a delivery capsule. The sheath slidably receives the inner shaft. A capsule proximal zone is attached to the sheath. A capsule distal zone is configured to transition between normal and flared states. A diameter of the distal zone is greater in the flared state, and the capsule includes a shape memory component that naturally assumes the normal state. The device is operable to perform a reversible partial deployment procedure in which a portion of the prosthesis is exposed distal the capsule and allowed to radially expand. Subsequently, with distal advancement of the capsule, the distal zone transitions to the flared state and imparts a collapsing force onto the prosthesis, causing the prosthesis to radially collapse and become recaptured within the delivery capsule. The capsule can include a laser cut tube encapsulated by a polymer.

摘要翻译： 一种经皮支架置入的瓣膜输送装置，包括内轴，护套和输送胶囊。 护套可滑动地容纳内轴。 胶囊近端区域附接到护套。 胶囊远端区域被配置为在正常和扩张状态之间转变。 远端区域的直径在扩张状态下较大，并且胶囊包括自然地呈现正常状态的形状记忆组件。 该装置可操作以执行可逆部分展开过程，其中假体的一部分暴露在胶囊的远端并允许径向扩张。 随后，随着胶囊的远端前进，远侧区域转变到扩张状态并且将塌陷力施加到假体上，导致假体径向折叠并在输送胶囊内重新捕获。 胶囊可以包括由聚合物包封的激光切割管。

公开(公告)号：US20120022628A1

公开(公告)日：2012-01-26

申请号：US12842496

申请日：2010-07-23

申请人： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

发明人： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

IPC分类号： A61F2/84

CPC分类号： A61F2/966 ,  A61F2/95 ,  A61F2002/9505

摘要： An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system.

摘要翻译： 公开了一种用于将支架耦合到输送系统的附接机构。 附接机构构造成相对于输送系统的内轴组件枢转，以将支架从输送系统释放。

公开(公告)号：US20120303111A1

公开(公告)日：2012-11-29

申请号：US13572319

申请日：2012-08-10

申请人： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

发明人： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

IPC分类号： A61F2/84

CPC分类号： A61F2/95 ,  A61F2/966 ,  A61F2002/9505

摘要： An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system.

公开(公告)号：US09192495B2

公开(公告)日：2015-11-24

申请号：US13572319

申请日：2012-08-10

申请人： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

发明人： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

IPC分类号： A61F2/95 ,  A61F2/966

CPC分类号： A61F2/95 ,  A61F2/966 ,  A61F2002/9505

摘要： An attachment mechanism for coupling a stent to a delivery system is disclosed. The delivery system includes an inner shaft assembly. The attachment mechanism is configured to pivot relative to the inner shaft assembly of the delivery system in order to release the stent from the delivery system upon retraction of a delivery sheath capsule compressively containing the stent.

摘要翻译： 公开了一种用于将支架耦合到输送系统的附接机构。 输送系统包括内轴组件。 附接机构构造成相对于输送系统的内轴组件枢转，以便在收缩包含该支架的输送护套胶囊收回时将支架从输送系统中释放。

公开(公告)号：US08876878B2

公开(公告)日：2014-11-04

申请号：US12842496

申请日：2010-07-23

申请人： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

发明人： Joshua Dwork ,  Hubert Yeung ,  Adam Shipley

IPC分类号： A61F2/97 ,  A61F2/95 ,  A61F2/966

CPC分类号： A61F2/966 ,  A61F2/95 ,  A61F2002/9505

摘要： An attachment mechanism for coupling a stent to a delivery system is disclosed. The attachment mechanism is configured to pivot relative to an inner shaft assembly of the delivery system in order to release the stent from the delivery system.

摘要翻译： 公开了一种用于将支架耦合到输送系统的附接机构。 附接机构构造成相对于输送系统的内轴组件枢转，以将支架从输送系统释放。

公开(公告)号：US09456899B2

公开(公告)日：2016-10-04

申请号：US14031330

申请日：2013-09-19

申请人： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

发明人： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

IPC分类号： A61F2/24 ,  A61M25/10

CPC分类号： A61F2/2433 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/95 ,  A61F2002/9534 ,  A61F2230/0054 ,  A61F2230/008 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61M25/1002 ,  A61M25/104 ,  A61M2025/1059

摘要： A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.

公开(公告)号：US08568474B2

公开(公告)日：2013-10-29

申请号：US13094455

申请日：2011-04-26

申请人： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

发明人： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

IPC分类号： A61F2/24

CPC分类号： A61F2/2433 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/95 ,  A61F2002/9534 ,  A61F2230/0054 ,  A61F2230/008 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61M25/1002 ,  A61M25/104 ,  A61M2025/1059

摘要： A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.

摘要翻译： 用于恢复（例如，更换）患者的有缺陷的心脏瓣膜的系统和方法。 操纵输送系统以经皮递送和植入支架假体心脏瓣膜至天然心脏瓣膜。 经扩张后的球囊经皮递送至植入部位，并且其顺从段布置在植入假体的区域内。 气囊膨胀使得顺应部分膨胀并接触假体，将假体的重建区域扩展至改造状态。 利用这些和相关技术，植入式支架假体心脏瓣膜的重塑是可能的，以提供许多益处，例如减少瓣膜泄漏的风险。

公开(公告)号：US20110264201A1

公开(公告)日：2011-10-27

申请号：US13094455

申请日：2011-04-26

申请人： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

发明人： Hubert Yeung ,  Mike Krivoruchko ,  Susheel Deshmukh

IPC分类号： A61F2/24

CPC分类号： A61F2/2433 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/95 ,  A61F2002/9534 ,  A61F2230/0054 ,  A61F2230/008 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61M25/1002 ,  A61M25/104 ,  A61M2025/1059

摘要： A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.

摘要翻译： 用于恢复（例如，更换）患者的有缺陷的心脏瓣膜的系统和方法。 操纵输送系统以经皮递送和植入支架假体心脏瓣膜至天然心脏瓣膜。 经扩张后的球囊经皮递送至植入部位，并且其顺从段布置在植入假体的区域内。 气囊膨胀使得顺应部分膨胀并接触假体，将假体的重建区域扩展至改造状态。 利用这些和相关技术，植入式支架假体心脏瓣膜的重塑是可能的，以提供许多益处，例如减少瓣膜泄漏的风险。

公开(公告)号：US20140039610A1

公开(公告)日：2014-02-06

申请号：US14031330

申请日：2013-09-19

申请人： Hubert Yeung ,  MIKE KRIVORUCHKO ,  SUSHEEL DESHMUKH

发明人： Hubert Yeung ,  MIKE KRIVORUCHKO ,  SUSHEEL DESHMUKH

IPC分类号： A61F2/24

CPC分类号： A61F2/2433 ,  A61F2/2418 ,  A61F2/2436 ,  A61F2/95 ,  A61F2002/9534 ,  A61F2230/0054 ,  A61F2230/008 ,  A61F2250/0018 ,  A61F2250/0039 ,  A61M25/1002 ,  A61M25/104 ,  A61M2025/1059

摘要： A system and method for restoring (e.g., replacing) a defective heart valve of a patient. A delivery system is manipulated to percutaneously deliver and implant a stented prosthetic heart valve to a native heart valve. A post-dilatation balloon is percutaneously delivered to the implantation site, and a compliant segment thereof is arranged within a region of the implanted prosthesis. The balloon is inflated such that the compliant segment expands and contacts the prosthesis, expanding a remodeling region of the prosthesis to a remodeled state. With these and related techniques, remodeling of an implanted, stented prosthetic heart valve to better match the native valve shape is possible, providing many benefits such as reducing the risk of paravalvular leaks.

摘要翻译： 用于恢复（例如，更换）患者的有缺陷的心脏瓣膜的系统和方法。 操纵输送系统以经皮递送和植入支架假体心脏瓣膜至天然心脏瓣膜。 经扩张后的球囊经皮递送至植入部位，并且其顺从段布置在植入假体的区域内。 气囊膨胀使得顺应部分膨胀并接触假体，将假体的重建区域扩展至改造状态。 利用这些和相关技术，植入式支架假体心脏瓣膜的重塑是可能的，以提供许多益处，例如减少瓣膜泄漏的风险。