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公开(公告)号：US20110208228A1
公开(公告)日：2011-08-25
申请号：US13005444
申请日：2011-01-12
IPC分类号： A61M29/02
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/12136 , A61B17/12172 , A61B2017/00809 , A61B2017/12054 , A61F2002/043
摘要： Systems and devices for minimally invasively treating an air leak in a lung comprise the steps of detecting an air leak in a lung; locating an airway in fluid communication with the air leak, introducing a bronchoscope into a patient's airway to a position adjacent the target section and occluding an airway upstream of the air leak for a period of time. The airway occlusion device is preferably removed after the air leak has substantially permanently healed. The occluding device may be a one-way valve. The occluding device may also comprise strut members and anchors that penetrate an airway wall.
摘要翻译： 用于微创侵入性地治疗肺部空气泄漏的系统和装置包括检测肺中的空气泄漏的步骤; 定位与空气泄漏流体连通的气道，将支气管镜引入患者的气道中至与目标部分相邻的位置，并在空气泄漏上游封闭气道一段时间。 在气体泄漏基本上永久愈合之后，优选除去气道阻塞装置。 闭塞装置可以是单向阀。 闭塞装置还可以包括穿透气道壁的支柱构件和锚固件。
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公开(公告)号：US07887585B2
公开(公告)日：2011-02-15
申请号：US12398122
申请日：2009-03-04
IPC分类号： A61F2/20
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/12136 , A61B17/12172 , A61B2017/00809 , A61B2017/12054 , A61F2002/043
摘要： Systems and devices for minimally invasively treating an air leak in a lung comprise the steps of detecting an air leak in a lung; locating an airway in fluid communication with the air leak, introducing a bronchoscope into a patient's airway to a position adjacent the target section and occluding an airway upstream of the air leak for a period of time. The airway occlusion device is preferably removed after the air leak has substantially permanently healed. The occluding device may be a one-way valve. The occluding device may also comprise strut members and anchors that penetrate an airway wall.
摘要翻译： 用于微创侵入性地治疗肺部空气泄漏的系统和装置包括检测肺中的空气泄漏的步骤; 定位与空气泄漏流体连通的气道，将支气管镜引入患者的气道中至与目标部分相邻的位置，并在空气泄漏上游封闭气道一段时间。 在气体泄漏基本上永久愈合之后，优选除去气道阻塞装置。 闭塞装置可以是单向阀。 闭塞装置还可以包括穿透气道壁的支柱构件和锚固件。
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公开(公告)号：US20090182369A1
公开(公告)日：2009-07-16
申请号：US12398122
申请日：2009-03-04
IPC分类号： A61M29/00
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/12136 , A61B17/12172 , A61B2017/00809 , A61B2017/12054 , A61F2002/043
摘要： Systems and devices for minimally invasively treating an air leak in a lung comprise the steps of detecting an air leak in a lung; locating an airway in fluid communication with the air leak, introducing a bronchoscope into a patient's airway to a position adjacent the target section and occluding an airway upstream of the air leak for a period of time. The airway occlusion device is preferably removed after the air leak has substantially permanently healed. The occluding device may be a one-way valve. The occluding device may also comprise strut members and anchors that penetrate an airway wall.
摘要翻译： 用于微创侵入性地治疗肺部空气泄漏的系统和装置包括检测肺中的空气泄漏的步骤; 定位与空气泄漏流体连通的气道，将支气管镜引入患者的气道中至与目标部分相邻的位置，并在空气泄漏上游封闭气道一段时间。 在气体泄漏基本上永久愈合之后，优选除去气道阻塞装置。 闭塞装置可以是单向阀。 闭塞装置还可以包括穿透气道壁的支柱构件和锚固件。
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公开(公告)号：US20110201956A1
公开(公告)日：2011-08-18
申请号：US12913257
申请日：2010-10-27
申请人： Clifton A. Alferness , Steven C. Springmeyer , Brandon James Shuman , William A. Sirokman , Hugo X. Gonzalez , Clinton L. Finger
发明人： Clifton A. Alferness , Steven C. Springmeyer , Brandon James Shuman , William A. Sirokman , Hugo X. Gonzalez , Clinton L. Finger
CPC分类号： A61B1/2676 , A61B1/267 , A61B5/0833 , A61B5/0878
摘要： Devices, systems, and methods for diagnosing physiological parameters of the lungs and treating associated medical conditions are disclosed herein. In particular, certain embodiments permit detection of air flow in lung passageways, air leaks, gas concentration (in particular oxygen), and temperature measurements. Measurements obtained using the devices, systems, and methods disclosed herein may also be used to determine optimal treatment sites for medical conditions such as emphysema, COPD, or lung volume reduction.
摘要翻译： 本文公开了用于诊断肺的生理参数和治疗相关医疗状况的装置，系统和方法。 特别地，某些实施例允许检测肺通道中的空气流，空气泄漏，气体浓度（特别是氧气）和温度测量。 使用本文公开的装置，系统和方法获得的测量也可用于确定医疗状况如肺气肿，COPD或肺体积减少的最佳治疗部位。
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公开(公告)号：US08667973B2
公开(公告)日：2014-03-11
申请号：US13286995
申请日：2011-11-01
IPC分类号： A61B19/00
CPC分类号： A61M16/00 , A61B17/12022 , A61B17/12104 , A61B17/12186 , A61F2002/043
摘要： A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.
摘要翻译： 一种以最小限度地侵入性地减少患病肺的超充气靶区段的体积的方法，包括以下步骤：将支气管镜引入患者的气道中至邻近目标区段的位置，并将目标区段内的空气与大气空气平衡至少部分 放气目标肺段; 将炎症引起物质注射到目标部分中以沉淀目标肺部分中的壁的粘附，通过在目标部分上游一段气道闭塞一段时间来防止目标部分的大量再膨胀，并且去除气道 目标部分的体积基本上永久减小后的闭塞。 注射的物质可以是自体血液或其组分。
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公开(公告)号：US08079368B2
公开(公告)日：2011-12-20
申请号：US12721426
申请日：2010-03-10
CPC分类号： A61M16/00 , A61B17/12022 , A61B17/12104 , A61B17/12186 , A61F2002/043
摘要： A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.
摘要翻译： 一种以最小限度地侵入性地减少患病肺的超充气靶区段的体积的方法，包括以下步骤：将支气管镜引入患者的气道中至邻近目标区段的位置，并将目标区段内的空气与大气空气平衡至少部分 放气目标肺段; 将炎症引起物质注射到目标部分中以沉淀目标肺部分中的壁的粘附，通过在目标部分上游一段气道闭塞一段时间来防止目标部分的大量再膨胀，并且去除气道 目标部分的体积基本上永久减小后的闭塞。 注射的物质可以是自体血液或其组分。
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公开(公告)号：US20100256714A1
公开(公告)日：2010-10-07
申请号：US12721426
申请日：2010-03-10
CPC分类号： A61M16/00 , A61B17/12022 , A61B17/12104 , A61B17/12186 , A61F2002/043
摘要： A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.
摘要翻译： 一种以最小限度地侵入性地减少患病肺的超充气靶区段的体积的方法，包括以下步骤：将支气管镜引入患者的气道中至邻近目标区段的位置，并将目标区段内的空气与大气空气平衡至少部分 放气目标肺段; 将炎症引起物质注射到目标部分中以沉淀目标肺部分中的壁的粘附，通过在目标部分上游一段气道闭塞一段时间来防止目标部分的大量再膨胀，并且去除气道 目标部分的体积基本上永久减小后的闭塞。 注射的物质可以是自体血液或其组分。
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公开(公告)号：US07100616B2
公开(公告)日：2006-09-05
申请号：US10409785
申请日：2003-04-08
IPC分类号： A61B19/00
CPC分类号： A61M16/00 , A61B17/12022 , A61B17/12104 , A61B17/12186 , A61F2002/043
摘要： A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.
摘要翻译： 一种以最小限度地侵入性地减少患病肺的超充气靶区段的体积的方法，包括以下步骤：将支气管镜引入患者的气道中至邻近目标区段的位置，并将目标区段内的空气与大气空气平衡至少部分 放气目标肺段; 将炎症引起物质注射到目标部分中以沉淀目标肺部分中的壁的粘附，通过在目标部分上游一段气道闭塞一段时间来防止目标部分的大量再膨胀，并且去除气道 目标部分的体积基本上永久减小后的闭塞。 注射的物质可以是自体血液或其组分。
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公开(公告)号：US20120101428A1
公开(公告)日：2012-04-26
申请号：US13286995
申请日：2011-11-01
IPC分类号： A61M37/00
CPC分类号： A61M16/00 , A61B17/12022 , A61B17/12104 , A61B17/12186 , A61F2002/043
摘要： A method of minimally invasively reducing a volume of a hyper-inflated target section of diseased lung comprising the steps of introducing a bronchoscope into a patient's airway to a position adjacent the target section and equilibrating air within the target section with atmospheric air to at least partially deflate the target lung section; injecting an inflammation-causing substance into the target section to precipitate adhesion of the walls within the target lung section, preventing substantial re-inflation of the target section by occluding an airway upstream of the target section for a period of time, and removing the airway occlusion after the target section has substantially permanently been reduced in volume. The injected substance can be autologous blood or a constituent thereof.
摘要翻译： 一种以最小限度地侵入性地减少患病肺的超充气靶区段的体积的方法，包括以下步骤：将支气管镜引入患者的气道中至邻近目标区段的位置，并将目标区段内的空气与大气空气平衡至少部分 放气目标肺段; 将炎症引起物质注射到目标部分中以沉淀目标肺部分中的壁的粘附，通过在目标部分上游一段气道闭塞一段时间来防止目标部分的大量再膨胀，并且去除气道 目标部分的体积基本上永久减小后的闭塞。 注射的物质可以是自体血液或其组分。
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