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    SYSTEM AND METHOD FOR IMPROVED REAL-TIME CINE IMAGING
    3.
    发明申请
    SYSTEM AND METHOD FOR IMPROVED REAL-TIME CINE IMAGING 有权
    改进的实时电影成像系统和方法

    公开(公告)号：US20090263001A1

    公开(公告)日：2009-10-22

    申请号：US12426113

    申请日：2009-04-17

    申请人： Yu Ding ,  Orlando P. Simonetti ,  Yiu-Cho Chung

    发明人： Yu Ding ,  Orlando P. Simonetti ,  Yiu-Cho Chung

    IPC分类号： G06K9/00 ,  G06K9/40

    CPC分类号： G06T5/007 ,  G06T5/002 ,  G06T2207/10076 ,  G06T2207/10088 ,  G06T2207/20182 ,  G06T2207/30048

    摘要： A cine imaging filter and method of use that includes a denoising image-filter based on the Karhunen-Loeve transform along the temporal direction to take advantage of the high temporal correlation among images. The cine imaging filter may further include the application of a simple formula describing the quantitative noise reduction capabilities of the KLT filter as a function of eigenimage cutoff. Additionally, the filter may validate its accuracy in numerical simulation and in in-vivo real time cine images. Furthermore, exemplary embodiments of the cine imaging filter may employ a technique to automatically select the optimal eigenimage cutoff to maximize noise reduction with minimal effect on image information.

    摘要翻译： 一种电影成像滤波器和使用方法，其包括沿着时间方向的基于Karhunen-Loeve变换的去噪图像滤波器，以利用图像之间的高时间相关性。 电影成像滤波器还可以包括应用描述KLT滤波器的定量降噪能力的简单公式作为本征图像截止的函数。 此外，滤波器可以验证其在数值模拟和体内实时电影图像中的准确性。 此外，电影成像滤波器的示例性实施例可以采用一种技术来自动选择最佳本征图像截止值以最大限度地降低噪点，而对图像信息的影响最小。

    SYSTEM AND METHOD FOR IMPROVED REAL-TIME CINE IMAGING
    4.
    发明申请
    SYSTEM AND METHOD FOR IMPROVED REAL-TIME CINE IMAGING 审中-公开
    改进的实时电影成像系统和方法

    公开(公告)号：US20120263365A1

    公开(公告)日：2012-10-18

    申请号：US13532377

    申请日：2012-06-25

    申请人： Yu Ding ,  Orlando P. Simonetti ,  Yiu-Cho Chung

    发明人： Yu Ding ,  Orlando P. Simonetti ,  Yiu-Cho Chung

    IPC分类号： G06K9/40

    CPC分类号： G06T5/007 ,  G06T5/002 ,  G06T2207/10076 ,  G06T2207/10088 ,  G06T2207/20182 ,  G06T2207/30048

    摘要： A cine imaging filter and method of use that includes a denoising image-filter based on the Karhunen-Loeve transform along the temporal direction to take advantage of the high temporal correlation among images. The cine imaging filter may further include the application of a simple formula describing the quantitative noise reduction capabilities of the KLT filter as a function of eigenimage cutoff. Additionally, the filter may validate its accuracy in numerical simulation and in in-vivo real time cine images. Furthermore, exemplary embodiments of the cine imaging filter may employ a technique to automatically select the optimal eigenimage cutoff to maximize noise reduction with minimal effect on image information.

    摘要翻译： 一种电影成像滤波器和使用方法，其包括沿着时间方向的基于Karhunen-Loeve变换的去噪图像滤波器，以利用图像之间的高时间相关性。 电影成像滤波器还可以包括应用描述KLT滤波器的定量降噪能力的简单公式作为本征图像截止的函数。 此外，滤波器可以验证其在数值模拟和体内实时电影图像中的准确性。 此外，电影成像滤波器的示例性实施例可以采用一种技术来自动选择最佳本征图像截止值以最大限度地降低噪点，而对图像信息的影响最小。

    System and method for improved real-time cine imaging
    6.
    发明授权
    System and method for improved real-time cine imaging 有权
    用于改进实时电影成像的系统和方法

    公开(公告)号：US08208709B2

    公开(公告)日：2012-06-26

    申请号：US12426113

    申请日：2009-04-17

    申请人： Yu Ding ,  Orlando P. Simonetti ,  Yiu-Cho Chung

    发明人： Yu Ding ,  Orlando P. Simonetti ,  Yiu-Cho Chung

    IPC分类号： G06K9/00

    CPC分类号： G06T5/007 ,  G06T5/002 ,  G06T2207/10076 ,  G06T2207/10088 ,  G06T2207/20182 ,  G06T2207/30048

    摘要： A cine imaging filter and method of use that includes a denoising image-filter based on the Karhunen-Loeve transform along the temporal direction to take advantage of the high temporal correlation among images. The cine imaging filter may further include the application of a simple formula describing the quantitative noise reduction capabilities of the KLT filter as a function of eigenimage cutoff. Additionally, the filter may validate its accuracy in numerical simulation and in in-vivo real time cine images. Furthermore, exemplary embodiments of the cine imaging filter may employ a technique to automatically select the optimal eigenimage cutoff to maximize noise reduction with minimal effect on image information.

    摘要翻译： 一种电影成像滤波器和使用方法，其包括沿着时间方向的基于Karhunen-Loeve变换的去噪图像滤波器，以利用图像之间的高时间相关性。 电影成像滤波器还可以包括应用描述KLT滤波器的定量降噪能力的简单公式作为本征图像截止的函数。 此外，滤波器可以验证其在数值模拟和体内实时电影图像中的准确性。 此外，电影成像滤波器的示例性实施例可以采用一种技术来自动选择最佳本征图像截止值以最大限度地降低噪点，而对图像信息的影响最小。

    Myocardial perfusion studies using magnetic resonance imaging
    8.
    发明授权
    Myocardial perfusion studies using magnetic resonance imaging 有权
    心肌灌注研究使用磁共振成像

    公开(公告)号：US06295465B1

    公开(公告)日：2001-09-25

    申请号：US09251550

    申请日：1999-02-17

    申请人： Orlando P. Simonetti

    发明人： Orlando P. Simonetti

    IPC分类号： A61B5055

    CPC分类号： G01R33/5601 ,  A61B5/055 ,  G01R33/563

    摘要： Gadolinium-based MR contrast agent is administered to a patient. Acquisition of MR data begins at the latest when the bolus of MR contrast agent reaches the patient's heart and continues throughout the first-pass of contrast agent through the coronary circulation. Advantageously, the acquisition is carried out using a T1-weighted, three-dimensional gradient echo sequence that is synchronized to the patient's cardiac cycle to acquire MR data only during diastole, and a T1-weighting magnetization preparation such as inversion-recovery or saturation-recovery is used.

    摘要翻译： 向患者施用基于钆的MR造影剂。 当MR造影剂的推注到达患者的心脏并且通过冠状动脉循环的造影剂的首次遍历时，MR数据的采集最迟开始。 有利的是，使用与患者心动周期同步的T1加权的三维梯度回波序列来进行采集，以仅在舒张期期间获取MR数据，以及T1加权磁化准备例如反转恢复或饱和 - 使用恢复。

    Display of three-dimensional MRA images in which arteries can be distinguished from veins
    10.
    发明授权
    Display of three-dimensional MRA images in which arteries can be distinguished from veins 失效
    显示动脉可以与静脉区分开的三维MRA图像

    公开(公告)号：US6073042A

    公开(公告)日：2000-06-06

    申请号：US937952

    申请日：1997-09-25

    申请人： Orlando P. Simonetti

    发明人： Orlando P. Simonetti

    IPC分类号： G01R33/54 ,  A61B5/055 ,  G01R33/28 ,  G01R33/48 ,  G01R33/563 ,  G06T1/00

    CPC分类号： G01R33/563 ,  A61B5/055 ,  G01R33/281

    摘要： An intravascular MR contrast agent is administered to a living patient. A series of three-dimensional dynamic MR datasets is acquired from the Volume of Interest ("VOI"), beginning after administration of the contrast agent and continuing for a sufficiently long time as to reflect contrast agent enhancement of all arterial and venous blood vessels within the VOI. A three-dimensional MR angiogram of the VOI is acquired after the contrast agent has reached equilibrium. For each voxel within the VOI, enhancement of that voxel as a function of time post administration of the contrast agent is computed. Parameters that distinguish enhancement of voxels relating to the patient's arteries from enhancement of voxels relating to the patient's veins are selected, and the intensity of each voxel in the MR angiogram is scaled in accordance with the selected parameters. A maximum intensity projection reconstruction of the VOI is generated from the MR angiogram in which voxel intensity has been scaled.

    摘要翻译： 向活体患者施用血管内MR造影剂。 从造影剂体系开始并持续足够长的时间，以反映所有动脉血管和静脉血管的造影剂增强，从感兴趣体积（“VOI”）中获取一系列三维动态MR数据集 VOI。 在造影剂达到平衡后，获取VOI的三维MR血管造影图。 对于VOI内的每个体素，计算作为造影剂的施用时间的函数的该体素的增强。 选择将与患者动脉相关的体素的增强与患者静脉相关的体素的增强区分开的参数，并且根据所选择的参数来缩放MR血管造影图中的每个体素的强度。 从其中已经缩放体素强度的MR血管造影图生成VOI的最大强度投影重建。