公开(公告)号：US20210246419A1

公开(公告)日：2021-08-12

申请号：US17159817

申请日：2021-01-27

申请人： Humacyte, Inc.

发明人： Shannon L.M. DAHL ,  Laura E. NIKLASON ,  Justin T. STRADER ,  William E. TENTE ,  Joseph J. LUNDQUIST ,  Juliana Blum ,  Heather L. Prichard

IPC分类号： C12N5/00 ,  A61L27/34 ,  A61F2/06 ,  A61F2/04 ,  B29C53/00 ,  B29C53/36 ,  A61L27/16 ,  A61L27/18 ,  A61L27/36 ,  A61L27/38 ,  A61L27/54 ,  A61L27/58

摘要： The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.

公开(公告)号：US20170135805A1

公开(公告)日：2017-05-18

申请号：US15420901

申请日：2017-01-31

申请人： Humacyte, Inc.

发明人： Shannon L.M. DAHL ,  Laura E. NIKLASON ,  Juliana BLUM ,  Justin T. STRADER ,  William E. TENTE ,  Heather L. PRICHARD ,  Joseph J. LUNDQUIST

IPC分类号： A61F2/06 ,  A61L27/16 ,  A61F2/04 ,  A61L27/36 ,  A61L27/38 ,  A61L27/54 ,  A61L27/58 ,  A61L27/18

摘要： The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.

公开(公告)号：US20180291333A1

公开(公告)日：2018-10-11

申请号：US16007322

申请日：2018-06-13

申请人： Humacyte, Inc.

发明人： Shannon L.M. DAHL ,  Laura E. NIKLASON ,  Justin T. STRADER ,  William E. TENTE ,  Joseph J. LUNDQUIST

IPC分类号： C12N5/00 ,  A61F2/04 ,  A61F2/06 ,  B29C53/00 ,  B29C53/36 ,  A61L27/34 ,  B29K105/00 ,  B29K67/00 ,  B29L23/00 ,  B29L31/00

摘要： The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.

公开(公告)号：US20180251727A1

公开(公告)日：2018-09-06

申请号：US15974195

申请日：2018-05-08

申请人： Humacyte, Inc.

发明人： Shannon L.M. DAHL ,  Laura E. NIKLASON ,  Justin T. STRADER ,  William E. TENTE ,  Joseph J. LUNDQUIST

IPC分类号： C12N5/00 ,  A61F2/04 ,  A61F2/06 ,  B29C53/00 ,  B29C53/36 ,  A61L27/34 ,  B29K105/00 ,  B29K67/00 ,  B29L23/00 ,  B29L31/00

摘要： The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.