公开(公告)号：US20210100474A1

公开(公告)日：2021-04-08

申请号：US17065344

申请日：2020-10-07

Applicant: Hyperfine Research, Inc.

Inventor： Hadrien A. Dyvorne ,  Laura Sacolick ,  Carole Lazarus ,  Eddy B. Boskamp ,  Jeremy Christopher Jordan

IPC: A61B5/055 ,  G01R33/381 ,  G01R33/385 ,  G01R33/36 ,  G01R33/44 ,  G01R33/34

Abstract: A magnetic resonance (MR) imaging system, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, and a sensor configured to detect electromagnetic interference conducted by a patient into an imaging region of the MR imaging system. The sensor may comprise at least one electrical conductor configured for electrically coupling to the patient. The MR imaging system may further comprise a noise reduction system configured to receive the electromagnetic interference from the sensor and to suppress electromagnetic interference in detected MR signals received by the MR imaging system based on the electromagnetic interference detected by the sensor.

公开(公告)号：US20210124003A1

公开(公告)日：2021-04-29

申请号：US17078788

申请日：2020-10-23

Applicant: Hyperfine Research, Inc.

Inventor： Carole Lazarus ,  Rafael O'Halloran ,  Hadrien A. Dyvorne

IPC: G01R33/565 ,  G01R33/48 ,  G01R33/36 ,  G01R33/56

Abstract: Techniques of prospectively compensating for motion of a subject being imaged by an MRI system, the MRI system comprising a plurality of magnetics components including at least one gradient coil and at least one radio-frequency (RF) coil, the techniques comprising: obtaining first spatial frequency data and second spatial frequency data by operating the MRI system in accordance with a pulse sequence, wherein the pulse sequence is associated with a sampling path that includes at least two non-contiguous portions each for sampling a central region of k-space; determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data; correcting the pulse sequence using the determined transformation to obtain a corrected pulse sequence; and obtaining additional spatial frequency data in accordance with the corrected pulse sequence.

公开(公告)号：US20210302518A1

公开(公告)日：2021-09-30

申请号：US17210351

申请日：2021-03-23

Applicant: Hyperfine Research, Inc.

Inventor： Hadrien A. Dyvorne ,  Laura Sacolick ,  Rafael O'Halloran ,  Carole Lazarus ,  Michael Twieg

IPC: G01R33/385 ,  G01R33/54 ,  G01R33/44 ,  G01R33/383

Abstract: Systems and methods for generating a gradient waveform for use by a low-field MRI system to generate a gradient magnetic field are provided herein. The gradient waveform can be determined using first information indicative of the gradient waveform and second information indicative of hardware constraints of the low-field MRI system including a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil. In some embodiments, the gradient waveform can be a trapezoidal gradient waveform determined to have a non-linear ramp-up portion and/or a non-linear ramp-down portion.

公开(公告)号：US20210124002A1

公开(公告)日：2021-04-29

申请号：US17078729

申请日：2020-10-23

Applicant: Hyperfine Research, Inc.

Inventor： Carole Lazarus

IPC: G01R33/565 ,  G01R33/56 ,  G01R33/561 ,  G06T11/00

Abstract: Techniques for compensating magnetic resonance imaging (MRI) data for artefacts caused by motion of a subject being imaged. The techniques include obtaining spatial frequency data obtained by using a magnetic resonance imaging (MRI) system to perform MRI on a patient, the spatial frequency data including first spatial frequency data and second spatial frequency data; determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data; determining a residual spatial phase; correcting, using the transformation, second spatial frequency data and the residual spatial phase, to obtain corrected second spatial frequency data and a corrected residual spatial phase; and generating a magnetic resonance (MR) image using the corrected second spatial frequency data and the corrected residual spatial phase.

公开(公告)号：US20200289019A1

公开(公告)日：2020-09-17

申请号：US16817370

申请日：2020-03-12

Applicant: Hyperfine Research, Inc.

Inventor： Jo Schlemper ,  Seyed Sadegh Moshen Salehi ,  Michal Sofka ,  Prantik Kundu ,  Carole Lazarus ,  Hadrien A. Dyvorne ,  Rafael O'Halloran ,  Laura Sacolick

IPC: A61B5/055 ,  G06N3/08 ,  G06N3/04 ,  G01R33/561

Abstract: Techniques for generating magnetic resonance (MR) images of a subject from MR data obtained by a magnetic resonance imaging (MRI) system, the techniques include: obtaining input MR spatial frequency data obtained by imaging the subject using the MRI system; generating an MR image of the subject from the input MR spatial frequency data using a neural network model comprising: a pre-reconstruction neural network configured to process the input MR spatial frequency data; a reconstruction neural network configured to generate at least one initial image of the subject from output of the pre-reconstruction neural network; and a post-reconstruction neural network configured to generate the MR image of the subject from the at least one initial image of the subject.

公开(公告)号：US20210302519A1

公开(公告)日：2021-09-30

申请号：US17210374

申请日：2021-03-23

Applicant: Hyperfine Research, Inc.

Inventor： Hadrien A. Dyvorne ,  Laura Sacolick ,  Rafael O'Halloran ,  Carole Lazarus ,  Michael Twieg

IPC: G01R33/385 ,  G01R33/383 ,  G01R33/44 ,  G01R33/54

Abstract: Systems and methods for generating a gradient waveform for use by a low-field MRI system to generate a gradient magnetic field are provided herein. The gradient waveform can be determined using first information indicative of the gradient waveform and second information indicative of hardware constraints of the low-field MRI system including a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil. In some embodiments, the gradient waveform can be a trapezoidal gradient waveform determined to have a non-linear ramp-up portion and/or a non-linear ramp-down portion.

公开(公告)号：US20210124001A1

公开(公告)日：2021-04-29

申请号：US17077882

申请日：2020-10-22

Applicant: Hyperfine Research, Inc.

Inventor： Eddy B. Boskamp ,  Mark Joseph Tuccillo ,  Prantik Kundu ,  Mike Twieg ,  Rafael O'Halloran ,  Carole Lazarus

IPC: G01R33/565 ,  G01R33/58

Abstract: A device and method for detecting motion and position of a patient positioned within a magnetic resonance imaging system, the device including at least one sensor configured to be capacitively coupled to the patient during magnetic resonance imaging. The method includes, while a patient is positioned within a magnetic resonance imaging system, measuring a reflected power value indicative of an amount of power reflected by the at least one sensor in response to being driven by at least one RF signal, and determining, using the reflected power value, whether the patient has moved.

公开(公告)号：US20210123998A1

公开(公告)日：2021-04-29

申请号：US17078660

申请日：2020-10-23

Applicant: Hyperfine Research, Inc.

Inventor： Carole Lazarus ,  Rafael O'Halloran ,  Hadrien A. Dyvorne

IPC: G01R33/56 ,  G01R33/48 ,  G01R33/565

Abstract: A method of operating a low-field magnetic resonance imaging (MRI) system, the method comprising: obtaining an initial set of k-space phase-encoding coordinates; generating a sampling path through at least some of the k-space phase-encoding coordinates in the initial set to mitigate impact of eddy currents on operation of the low-field MRI system; and operating the low-field MRI system using a pulse sequence in accordance with the sampling path to obtain spatial frequency data for generating one or more magnetic resonance (MR) images of a subject.

公开(公告)号：US20210103017A1

公开(公告)日：2021-04-08

申请号：US17065356

申请日：2020-10-07

Applicant: Hyperfine Research, Inc.

Inventor： Hadrien A. Dyvorne ,  Laura Sacolick ,  Carole Lazarus ,  Eddy B. Boskamp ,  Jeremy Christopher Jordan

IPC: G01R33/28 ,  G01R33/422 ,  G01R33/34 ,  G01R29/08 ,  A61B5/055 ,  A61B5/00

Abstract: A magnetic resonance (MR) imaging system, comprising a magnetics system having a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, and a sensor configured to detect electromagnetic interference conducted by a patient into an imaging region of the MR imaging system. The sensor may comprise at least one electrical conductor configured for electrically coupling to the patient. The MR imaging system may further comprise a noise reduction system configured to receive the electromagnetic interference from the sensor and to suppress electromagnetic interference in detected MR signals received by the MR imaging system based on the electromagnetic interference detected by the sensor.