公开(公告)号：US20210048498A1

公开(公告)日：2021-02-18

申请号：US16994005

申请日：2020-08-14

Applicant: Hyperfine Research, Inc.

Inventor： Hadrien A. Dyvorne ,  Cedric Hugon ,  Rafael O'Halloran ,  Laura Sacolick

IPC: G01R33/565 ,  G01R33/58

Abstract: Techniques for compensating for presence of eddy currents during the operation of a magnetic resonance imaging (MRI) system in accordance with a pulse sequence, the pulse sequence comprising a gradient waveform associated with a target gradient field. The techniques include: compensating for presence of eddy currents during operation of the MRI system at least in part by correcting the gradient waveform using a nonlinear function of a characteristic of the gradient waveform to obtain a corrected gradient waveform; and operating the MRI system in accordance with the corrected gradient waveform to generate the target gradient field.

公开(公告)号：US20210124003A1

公开(公告)日：2021-04-29

申请号：US17078788

申请日：2020-10-23

Applicant: Hyperfine Research, Inc.

Inventor： Carole Lazarus ,  Rafael O'Halloran ,  Hadrien A. Dyvorne

IPC: G01R33/565 ,  G01R33/48 ,  G01R33/36 ,  G01R33/56

Abstract: Techniques of prospectively compensating for motion of a subject being imaged by an MRI system, the MRI system comprising a plurality of magnetics components including at least one gradient coil and at least one radio-frequency (RF) coil, the techniques comprising: obtaining first spatial frequency data and second spatial frequency data by operating the MRI system in accordance with a pulse sequence, wherein the pulse sequence is associated with a sampling path that includes at least two non-contiguous portions each for sampling a central region of k-space; determining a transformation using a first image obtained using the first spatial frequency data and a second image obtained using the second spatial frequency data; correcting the pulse sequence using the determined transformation to obtain a corrected pulse sequence; and obtaining additional spatial frequency data in accordance with the corrected pulse sequence.

公开(公告)号：US20200041588A1

公开(公告)日：2020-02-06

申请号：US16527327

申请日：2019-07-31

Applicant: Hyperfine Research, Inc.

Inventor： Rafael O'Halloran ,  Laura Sacolick

IPC: G01R33/381 ,  G01R33/563 ,  G01R33/389

Abstract: Methods and apparatus for operating a low-field magnetic resonance imaging (MRI) system to perform diffusion weighted imaging, the low-field MRI system including a plurality of magnetics components including a B0 magnet configured to produce a low-field main magnetic field B0, at least one gradient coil configured to, when operated, provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency (RF) component configured to acquire, when operated, the emitted magnetic resonance signals. The method comprises controlling one or more of the plurality of magnetics components in accordance with at least one pulse sequence having a diffusion-weighted gradient encoding period followed by multiple echo periods during which magnetic resonance signals are produced and detected, wherein at least two of the multiple echo periods correspond to respective encoded echoes having an opposite gradient polarity.

公开(公告)号：US20200289019A1

公开(公告)日：2020-09-17

申请号：US16817370

申请日：2020-03-12

Applicant: Hyperfine Research, Inc.

Inventor： Jo Schlemper ,  Seyed Sadegh Moshen Salehi ,  Michal Sofka ,  Prantik Kundu ,  Carole Lazarus ,  Hadrien A. Dyvorne ,  Rafael O'Halloran ,  Laura Sacolick

IPC: A61B5/055 ,  G06N3/08 ,  G06N3/04 ,  G01R33/561

Abstract: Techniques for generating magnetic resonance (MR) images of a subject from MR data obtained by a magnetic resonance imaging (MRI) system, the techniques include: obtaining input MR spatial frequency data obtained by imaging the subject using the MRI system; generating an MR image of the subject from the input MR spatial frequency data using a neural network model comprising: a pre-reconstruction neural network configured to process the input MR spatial frequency data; a reconstruction neural network configured to generate at least one initial image of the subject from output of the pre-reconstruction neural network; and a post-reconstruction neural network configured to generate the MR image of the subject from the at least one initial image of the subject.

公开(公告)号：US20200209334A1

公开(公告)日：2020-07-02

申请号：US16684976

申请日：2019-11-15

Applicant: Hyperfine Research, Inc.

Inventor： Rafael O'Halloran ,  Cedric Hugon ,  Laura Sacolick ,  Hadrien A. Dyvorne

IPC: G01R33/565 ,  G01R33/54 ,  G01R33/56

Abstract: An apparatus for controlling at least one gradient coil of a magnetic resonance imaging (MRI) system. The apparatus may include at least one computer hardware processor; and at least one computer-readable storage medium storing processor executable instructions that, when executed by the at least one computer hardware processor, cause the at least one computer hardware processor to perform a method. The method may include receiving information specifying at least one target pulse sequence; determining a corrected pulse sequence to control the at least one gradient coil based on the at least one target pulse sequence and a hysteresis model of induced magnetization in the MRI system caused by operation of the at least one gradient coil; and controlling, using the corrected gradient pulse sequence, the at least one gradient coil to generate one or more gradient pulses for imaging a patient.

公开(公告)号：US20210302519A1

公开(公告)日：2021-09-30

申请号：US17210374

申请日：2021-03-23

Applicant: Hyperfine Research, Inc.

Inventor： Hadrien A. Dyvorne ,  Laura Sacolick ,  Rafael O'Halloran ,  Carole Lazarus ,  Michael Twieg

IPC: G01R33/385 ,  G01R33/383 ,  G01R33/44 ,  G01R33/54

Abstract: Systems and methods for generating a gradient waveform for use by a low-field MRI system to generate a gradient magnetic field are provided herein. The gradient waveform can be determined using first information indicative of the gradient waveform and second information indicative of hardware constraints of the low-field MRI system including a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil. In some embodiments, the gradient waveform can be a trapezoidal gradient waveform determined to have a non-linear ramp-up portion and/or a non-linear ramp-down portion.

公开(公告)号：US20210124001A1

公开(公告)日：2021-04-29

申请号：US17077882

申请日：2020-10-22

Applicant: Hyperfine Research, Inc.

Inventor： Eddy B. Boskamp ,  Mark Joseph Tuccillo ,  Prantik Kundu ,  Mike Twieg ,  Rafael O'Halloran ,  Carole Lazarus

IPC: G01R33/565 ,  G01R33/58

Abstract: A device and method for detecting motion and position of a patient positioned within a magnetic resonance imaging system, the device including at least one sensor configured to be capacitively coupled to the patient during magnetic resonance imaging. The method includes, while a patient is positioned within a magnetic resonance imaging system, measuring a reflected power value indicative of an amount of power reflected by the at least one sensor in response to being driven by at least one RF signal, and determining, using the reflected power value, whether the patient has moved.

公开(公告)号：US20210123998A1

公开(公告)日：2021-04-29

申请号：US17078660

申请日：2020-10-23

Applicant: Hyperfine Research, Inc.

Inventor： Carole Lazarus ,  Rafael O'Halloran ,  Hadrien A. Dyvorne

IPC: G01R33/56 ,  G01R33/48 ,  G01R33/565

Abstract: A method of operating a low-field magnetic resonance imaging (MRI) system, the method comprising: obtaining an initial set of k-space phase-encoding coordinates; generating a sampling path through at least some of the k-space phase-encoding coordinates in the initial set to mitigate impact of eddy currents on operation of the low-field MRI system; and operating the low-field MRI system using a pulse sequence in accordance with the sampling path to obtain spatial frequency data for generating one or more magnetic resonance (MR) images of a subject.

公开(公告)号：US20210302518A1

公开(公告)日：2021-09-30

申请号：US17210351

申请日：2021-03-23

Applicant: Hyperfine Research, Inc.

Inventor： Hadrien A. Dyvorne ,  Laura Sacolick ,  Rafael O'Halloran ,  Carole Lazarus ,  Michael Twieg

IPC: G01R33/385 ,  G01R33/54 ,  G01R33/44 ,  G01R33/383

Abstract: Systems and methods for generating a gradient waveform for use by a low-field MRI system to generate a gradient magnetic field are provided herein. The gradient waveform can be determined using first information indicative of the gradient waveform and second information indicative of hardware constraints of the low-field MRI system including a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil. In some embodiments, the gradient waveform can be a trapezoidal gradient waveform determined to have a non-linear ramp-up portion and/or a non-linear ramp-down portion.

公开(公告)号：US20210109174A1

公开(公告)日：2021-04-15

申请号：US17086869

申请日：2020-11-02

Applicant: Hyperfine Research, Inc.

Inventor： Rafael O'Halloran ,  Laura Sacolick

IPC: G01R33/381 ,  G01R33/389 ,  G01R33/563

Abstract: Methods and apparatus for operating a low-field magnetic resonance imaging (MRI) system to perform diffusion weighted imaging, the low-field MRI system including a plurality of magnetics components including a B0 magnet configured to produce a low-field main magnetic field B0, at least one gradient coil configured to, when operated, provide spatial encoding of emitted magnetic resonance signals, and at least one radio frequency (RF) component configured to acquire, when operated, the emitted magnetic resonance signals. The method comprises controlling one or more of the plurality of magnetics components in accordance with at least one pulse sequence having a diffusion-weighted gradient encoding period followed by multiple echo periods during which magnetic resonance signals are produced and detected, wherein at least two of the multiple echo periods correspond to respective encoded echoes having an opposite gradient polarity.