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    Coacervate having an ionic polymer mixed with the adhesive protein of a mussel or of a species of the variome thereof
    2.
    发明授权
    Coacervate having an ionic polymer mixed with the adhesive protein of a mussel or of a species of the variome thereof 失效
    具有与贻贝或其变体种的粘合蛋白混合的离子聚合物的凝聚体

    公开(公告)号：US08673986B2

    公开(公告)日：2014-03-18

    申请号：US13376001

    申请日：2010-08-06

    申请人： Hyung Joon Cha ,  Yoo Seong Choi ,  Dong Gyun Kang ,  Young Hoon Song ,  Seonghye Lim ,  Bong-Hyuk Choi

    发明人： Hyung Joon Cha ,  Yoo Seong Choi ,  Dong Gyun Kang ,  Young Hoon Song ,  Seonghye Lim ,  Bong-Hyuk Choi

    IPC分类号： A61K47/30

    CPC分类号： C07K14/43504

    摘要： The present invention relates to a coacervate comprising a mussel adhesive protein and an anionic polymer, and more particularly, to a coacervate prepared by mixing a mussel adhesive protein with an anionic polymer, and a novel use thereof. In the present invention, a coacervate prepared by mixing a mussel adhesive protein and an anionic polymer shows a very excellent adhesive strength to various substrates such as cells or metals, and is able to maintain its adhesive strength in the presence of water or under water, thereby being effectively used as an adhesive. Moreover, it has an activity capable of encapsulating bioactive materials, thereby being effectively used as an active component of a composition for delivering bioactive materials.

    摘要翻译： 本发明涉及包含贻贝粘合蛋白和阴离子聚合物的凝聚层，更具体地，涉及通过将贻贝粘合蛋白与阴离子聚合物混合制备的凝聚层及其新用途。 在本发明中，通过混合贻贝粘合蛋白质和阴离子聚合物制备的凝聚层对各种底物如细胞或金属显示非常优异的粘合强度，并且能够在水或水下存在下保持其粘合强度， 从而有效地用作粘合剂。 此外，它具有能够包封生物活性材料的活性，从而有效地用作用于递送生物活性材料的组合物的活性组分。