公开(公告)号：US20140113325A1

公开(公告)日：2014-04-24

申请号：US13802626

申请日：2013-03-13

Applicant: I-SHOU UNIVERSITY

Inventor： Jau-Yann Wu ,  Li-Feng Liu ,  Kuan-Ju Pan ,  Hao-Yu Tseng ,  Jian-Ching Wu

IPC: C12Q1/04 ,  G01N33/94 ,  C12Q1/02 ,  G01N33/50

CPC classification number: C12Q1/04 ,  C12Q1/02 ,  C12Q1/025 ,  G01N33/50 ,  G01N33/5044 ,  G01N33/5091 ,  G01N33/569 ,  G01N33/574 ,  G01N33/582 ,  G01N33/94 ,  G01N2400/00 ,  G01N2500/00

Abstract: The disclosure provides a use of a fluorescent saccharide-based derivative in cell detection. The fluorescent saccharide-based derivative is obtained from a reactive material through an imine formation reaction, and the reactive material is selected from a composition (A) or a composition (B). The composition (A) includes a reducing sugar compound and an amino group-containing compound having at least one primary amino group. The composition (B) includes an amino sugar compound and a carbonyl group-containing compound, and the amino sugar compound contains at least one primary amino group.

Abstract translation: 本公开提供了基于荧光糖的衍生物在细胞检测中的用途。 荧光糖基衍生物通过亚胺形成反应由反应性材料获得，反应性材料选自组合物（A）或组合物（B）。 组合物（A）包括还原糖化合物和具有至少一个伯氨基的含氨基化合物。 组合物（B）包括氨基糖化合物和含羰基化合物，氨基糖化合物含有至少一个伯氨基。

公开(公告)号：US08895261B2

公开(公告)日：2014-11-25

申请号：US13802626

申请日：2013-03-13

Applicant: I-Shou University

Inventor： Jau-Yann Wu ,  Li-Feng Liu ,  Kuan-Ju Pan ,  Hao-Yu Tseng ,  Jian-Ching Wu

IPC: C12Q1/04 ,  C12Q1/02 ,  G01N33/94 ,  G01N33/50

CPC classification number: C12Q1/04 ,  C12Q1/02 ,  C12Q1/025 ,  G01N33/50 ,  G01N33/5044 ,  G01N33/5091 ,  G01N33/569 ,  G01N33/574 ,  G01N33/582 ,  G01N33/94 ,  G01N2400/00 ,  G01N2500/00

Abstract: The disclosure provides a use of a fluorescent saccharide-based derivative in cell detection. The fluorescent saccharide-based derivative is obtained from a reactive material through an imine formation reaction, and the reactive material is selected from a composition (A) or a composition (B). The composition (A) includes a reducing sugar compound and an amino group-containing compound having at least one primary amino group. The composition (B) includes an amino sugar compound and a carbonyl group-containing compound, and the amino sugar compound contains at least one primary amino group.

Abstract translation: 本公开提供了基于荧光糖的衍生物在细胞检测中的用途。 荧光糖基衍生物通过亚胺形成反应由反应性材料获得，反应性材料选自组合物（A）或组合物（B）。 组合物（A）包括还原糖化合物和具有至少一个伯氨基的含氨基化合物。 组合物（B）包括氨基糖化合物和含羰基化合物，氨基糖化合物含有至少一个伯氨基。