公开(公告)号：US20240002896A1

公开(公告)日：2024-01-04

申请号：US18250406

申请日：2021-10-27

Applicant: IDEMITSU KOSAN CO.,LTD.

Inventor： Kazuyoshi KOIKE ,  Seika OIWA

IPC: C12P21/02 ,  C07K7/06 ,  C07K5/083 ,  C07K5/097 ,  C07K5/09 ,  C07K5/08 ,  C07K5/10

CPC classification number: C12P21/02 ,  C07K7/06 ,  C07K5/0804 ,  C07K5/0821 ,  C07K5/0817 ,  C07K5/0802 ,  C07K5/10 ,  C07K2319/00

Abstract: A peptide of 3 to 8 amino acid residues may include the sequence:


XmZnPUq  (I),

wherein P is proline, Z is independently a lysine (K) and/or asparagine (N) residue, X is an amino acid residue independently selected from isoleucine (I), phenylalanine (F), methionine (M), alanine (A), valine (V), tryptophan (W), tyrosine (Y), histidine (H), cysteine (C), arginine (R), glutamine (Q) and serine (S), U is an amino acid residue independently selected from arginine (R), glycine (G), serine (S), lysine (K), threonine (T), leucine (L), asparagine (N), histidine (H) and isoleucine (I), m is 0, 1, 2 or 3, n is 1 or 2, and q is 0, 1, 2 or 3.

公开(公告)号：US20230365979A1

公开(公告)日：2023-11-16

申请号：US18246917

申请日：2021-09-28

Applicant: IDEMITSU KOSAN CO.,LTD.

Inventor： Kazuyoshi KOIKE ,  Seika OIWA

IPC: C12N15/62 ,  C12P21/02 ,  C12N15/70 ,  C12N15/81 ,  C07K14/00

CPC classification number: C12N15/62 ,  C12P21/02 ,  C12N15/70 ,  C12N15/815 ,  C07K14/00 ,  C07K2319/00

Abstract: A peptide of 6 to 50 amino acid residues comprising the following sequence:


Xm(JYn)qJZr  (I)



wherein J is an amino acid residue selected from Q (glutamine), E (glutamic acid), and G (glycine);
X and Y are each an amino acid residue independently selected from arginine (R), glycine (G), serine (S), lysine (K), threonine (T), leucine (L), asparagine (N), glutamine(Q), histidine (H), proline (P), isoleucine (I), valine (V), alanine (A), and methionine (M) with the proviso that X and Y are each other than Q in the case of said peptide containing Q as J and X and Y are each other than G in the case of said peptide containing G as J, and
at least one Y in each repeating unit JYn is K, L, N, Q, H or R;
Z is an amino acid residue independently selected from R, G, S, K, T, N, Q, H and P with the proviso that Z is other than Q in the case of said peptide containing Q as J and Z is other than G in the case of said peptide containing G as J;
the number of P's contained in the peptide is 0 or 1; and
m is an integer of 0 to 6, n is 1, 2 or 3, q is an integer of 1 to 10, and r is an integer of 0 to 10.